2014-05-22 release

Chris Mungall

2014-05-22 release

Various new terms from Phenoscape, including tooth types and ridges

Ontology Diff Report

Teeth:
- Added multiple tooth ridge classes
- Added synonyms for teeth (e.g. decidious / primary)
- Added missing combos in {upper,lower}{primary,secondary}{CIPM} tooth pattern
Skeleton
- NT: bony tubercle
- Added syns for subsections of vertebral column
- merged ‘optic foramen’ (embryonic) into optic canal
- NT: fibula metaphysis. Fixes issue #455
Admin
- split many comments into separate properties: function notes, curator notes, editor notes
- ID typo fixed. Fixes issue #456
various NTs for phenotype definitions
Development
- Weakened spatial disjointness constraint between Emb and Extra-Emb. See https://github.com/obophenotype/mouse-anatomy-ontology/issues/3
- more axioms for staging relations
Integration
- NTs for epithelia and muscle of rectum analogs in inverts. Some FBbt and Wbbt classes should auto-classify here
- made EMAPA axioms taxon-equivalent

Original Ontology

IRI: http://purl.obolibrary.org/obo/uberon.owl
VersionIRI: http://purl.obolibrary.org/obo/uberon/releases/2014-05-16/uberon.owl

New Ontology

IRI: http://purl.obolibrary.org/obo/uberon.owl
VersionIRI: http://purl.obolibrary.org/obo/uberon/releases/2014-05-22/uberon.owl

Report for classes

Class objects lost from source: 1

optic foramen

Class objects new in target: 44

New Class : shoulder joint

shoulder joint EquivalentTo skeletal joint and part of some shoulder
shoulder joint id UBERON:0016884
shoulder joint SubClassOf develops from some shoulder joint primordium
shoulder joint SubClassOf part of some shoulder
shoulder joint definition The joint that is formed by the union of the humerus, the scapula (or shoulder blade), and the clavicle (or collarbone). Commonly thought of as a single joint, the shoulder is actually made up of two separate joints - the glenohumeral and acromioclavicular joints { database cross reference=http://www.innerbody.com/image/skel17.html }
shoulder joint database cross reference http://www.snomedbrowser.com/Codes/Details/361835002
shoulder joint has exact synonym joint of shoulder region
shoulder joint SubClassOf skeletal joint
shoulder joint has obo namespace uberon
shoulder joint label shoulder joint

New Class : transitional anatomical structure

transitional anatomical structure SubClassOf developing anatomical structure
transitional anatomical structure label transitional anatomical structure
transitional anatomical structure id UBERON:0016888
transitional anatomical structure definition An embryonic anatomical entity that will turn into one or more other anatomical entities, perhaps with other anatomical entities, later in development. { database cross reference=AEO:0000132 , database cross reference=AEO:JB }
transitional anatomical structure has obo namespace uberon
transitional anatomical structure database cross reference AEO:0000132

New Class : entire extraembryonic component

entire extraembryonic component SubClassOf part of some conceptus
entire extraembryonic component definition The part of the conceptus that may be lost before birth or will be discarded at birth, or when the embryo becomes an independent organism. { database cross reference=AEO:0000195 , database cross reference=AEO:JB }
entire extraembryonic component has exact synonym extraembryonic component { database cross reference=AEO:0000195 }
entire extraembryonic component has obo namespace uberon
entire extraembryonic component database cross reference EMAPA:16042
entire extraembryonic component label entire extraembryonic component
entire extraembryonic component SubClassOf multi-tissue structure
entire extraembryonic component SubClassOf existence starts and ends during some embryo stage
entire extraembryonic component has exact synonym extra-embryonic component
entire extraembryonic component id UBERON:0016887
entire extraembryonic component database cross reference AEO:0000195
entire extraembryonic component SubClassOf adjacent to some embryonic structure

New Class : muscle of terminal part of digestive tract

muscle of terminal part of digestive tract definition Any muscle structure of the distalmost portion of the digestive tract. { database cross reference=UBERON:cjm }
muscle of terminal part of digestive tract EquivalentTo muscle structure and part of some terminal part of digestive tract
muscle of terminal part of digestive tract has narrow synonym rectum muscle structure
muscle of terminal part of digestive tract id UBERON:0016886
muscle of terminal part of digestive tract SubClassOf muscle structure
muscle of terminal part of digestive tract SubClassOf part of some terminal part of digestive tract
muscle of terminal part of digestive tract has narrow synonym rectum muscle
muscle of terminal part of digestive tract has obo namespace uberon
muscle of terminal part of digestive tract label muscle of terminal part of digestive tract

New Class : periosteum of long bone

periosteum of long bone SubClassOf periosteum
periosteum of long bone SubClassOf part of some long bone
periosteum of long bone has obo namespace uberon
periosteum of long bone EquivalentTo periosteum and part of some long bone
periosteum of long bone has exact synonym long bone periosteum { database cross reference=FMA:32677 }
periosteum of long bone database cross reference FMA:32677
periosteum of long bone id UBERON:0016896
periosteum of long bone label periosteum of long bone

New Class : intrahepatic branch of portal vein

intrahepatic branch of portal vein database cross reference http://www.snomedbrowser.com/Codes/Details/304373004
intrahepatic branch of portal vein has exact synonym intrahepatic part of portal vein { database cross reference=FMA:15417 }
intrahepatic branch of portal vein database cross reference FMA:15417
intrahepatic branch of portal vein SubClassOf vein of abdomen
intrahepatic branch of portal vein has obo namespace uberon
intrahepatic branch of portal vein id UBERON:0016890
intrahepatic branch of portal vein label intrahepatic branch of portal vein
intrahepatic branch of portal vein SubClassOf part of some liver
intrahepatic branch of portal vein SubClassOf liver blood vessel

New Class : rostral margin of orbit

rostral margin of orbit SubClassOf zone of bone organ
rostral margin of orbit id UBERON:0016942
rostral margin of orbit has alternative id http://purl.bioontology.org/ontology/provisional/58938a8e-359c-49d8-b3f7-5e1fd7e1a109
rostral margin of orbit has obo namespace uberon
rostral margin of orbit SubClassOf part of some orbit
rostral margin of orbit has alternative id BSPOTEMP:58938a8e-359c-49d8-b3f7-5e1fd7e1a109
rostral margin of orbit label rostral margin of orbit
rostral margin of orbit SubClassOf neural crest-derived structure

New Class : upper premolar tooth

upper premolar tooth id UBERON:0016944
upper premolar tooth has obo namespace uberon
upper premolar tooth has alternative id UBERON:4200144
upper premolar tooth has exact synonym upper premolar tooth
upper premolar tooth label upper premolar tooth
upper premolar tooth SubClassOf premolar tooth
upper premolar tooth has exact synonym maxillary premolar tooth
upper premolar tooth SubClassOf tooth of upper jaw
upper premolar tooth has broad synonym UP { has synonym type=abbreviation }
upper premolar tooth EquivalentTo premolar tooth and part of some upper jaw region
upper premolar tooth SubClassOf part of some upper jaw region

New Class : lower premolar tooth

lower premolar tooth has alternative id UBERON:4200143
lower premolar tooth id UBERON:0016943
lower premolar tooth SubClassOf part of some lower jaw region
lower premolar tooth SubClassOf tooth of lower jaw
lower premolar tooth SubClassOf premolar tooth
lower premolar tooth EquivalentTo premolar tooth and part of some lower jaw region
lower premolar tooth has exact synonym lower premolar tooth
lower premolar tooth label lower premolar tooth
lower premolar tooth has broad synonym LP { has synonym type=abbreviation }
lower premolar tooth has exact synonym mandibular premolar tooth
lower premolar tooth has obo namespace uberon

New Class : mesial marginal ridge of tooth

mesial marginal ridge of tooth has obo namespace uberon
mesial marginal ridge of tooth has exact synonym mesial marginal ridge of tooth
mesial marginal ridge of tooth label mesial marginal ridge of tooth
mesial marginal ridge of tooth SubClassOf marginal ridge of tooth
mesial marginal ridge of tooth id UBERON:0016938
mesial marginal ridge of tooth database cross reference http://www.snomedbrowser.com/Codes/Details/278475009

New Class : distal marginal ridge of tooth

distal marginal ridge of tooth has obo namespace uberon
distal marginal ridge of tooth label distal marginal ridge of tooth
distal marginal ridge of tooth database cross reference http://www.snomedbrowser.com/Codes/Details/278476005
distal marginal ridge of tooth id UBERON:0016939
distal marginal ridge of tooth has exact synonym distal marginal ridge of tooth
distal marginal ridge of tooth SubClassOf marginal ridge of tooth

New Class : transverse marginal ridge of tooth

transverse marginal ridge of tooth SubClassOf marginal ridge of tooth
transverse marginal ridge of tooth id UBERON:0016937
transverse marginal ridge of tooth database cross reference http://www.snomedbrowser.com/Codes/Details/245702002
transverse marginal ridge of tooth label transverse marginal ridge of tooth
transverse marginal ridge of tooth has exact synonym transverse marginal ridge of tooth
transverse marginal ridge of tooth has obo namespace uberon

New Class : marginal ridge of tooth

marginal ridge of tooth database cross reference http://www.snomedbrowser.com/Codes/Details/245700005
marginal ridge of tooth id UBERON:0016934
marginal ridge of tooth has obo namespace uberon
marginal ridge of tooth database cross reference FMA:56758
marginal ridge of tooth label marginal ridge of tooth
marginal ridge of tooth has exact synonym crista marginalis (dentis) { database cross reference=FMA:56758 }
marginal ridge of tooth has exact synonym crista marginalis of tooth { database cross reference=FMA:56758 }
marginal ridge of tooth SubClassOf ridge of tooth

New Class : oblique ridge of tooth

oblique ridge of tooth database cross reference http://www.snomedbrowser.com/Codes/Details/245701009
oblique ridge of tooth database cross reference FMA:56660
oblique ridge of tooth label oblique ridge of tooth
oblique ridge of tooth SubClassOf ridge of tooth
oblique ridge of tooth has exact synonym oblique ridge of crown of tooth { database cross reference=FMA:56660 }
oblique ridge of tooth has obo namespace uberon
oblique ridge of tooth id UBERON:0016933
oblique ridge of tooth has exact synonym crista obliqua (corona dentis) { database cross reference=FMA:56660 }

New Class : triangular ridge of tooth

triangular ridge of tooth has exact synonym crista triangularis of tooth { database cross reference=FMA:56659 }
triangular ridge of tooth id UBERON:0016932
triangular ridge of tooth has exact synonym crista triangularis (corona dentis) { database cross reference=FMA:56659 }
triangular ridge of tooth label triangular ridge of tooth
triangular ridge of tooth has obo namespace uberon
triangular ridge of tooth has exact synonym triangular ridge of crown of tooth { database cross reference=FMA:56659 }
triangular ridge of tooth database cross reference FMA:56659
triangular ridge of tooth SubClassOf ridge of tooth

New Class : transverse ridge of tooth

transverse ridge of tooth id UBERON:0016931
transverse ridge of tooth has exact synonym transverse ridge of crown of tooth { database cross reference=FMA:56658 }
transverse ridge of tooth SubClassOf ridge of tooth
transverse ridge of tooth has obo namespace uberon
transverse ridge of tooth has exact synonym crista transversalis (corona dentis) { database cross reference=FMA:56658 }
transverse ridge of tooth database cross reference FMA:56658
transverse ridge of tooth has exact synonym crista transversalis of tooth { database cross reference=FMA:56658 }
transverse ridge of tooth has alternative id UBERONTEMP:12cd474b-52d2-46e2-9a3d-2322edc3490b
transverse ridge of tooth label transverse ridge of tooth

New Class : ridge of tooth

ridge of tooth has obo namespace uberon
ridge of tooth label ridge of tooth
ridge of tooth has exact synonym tooth ridge
ridge of tooth has exact synonym crista of tooth
ridge of tooth SubClassOf structure with developmental contribution from neural crest
ridge of tooth database cross reference http://www.snomedbrowser.com/Codes/Details/245699009
ridge of tooth SubClassOf part of some calcareous tooth
ridge of tooth SubClassOf ectoderm-derived structure
ridge of tooth id UBERON:0016930
ridge of tooth SubClassOf skeletal element projection

New Class : preductal region of aortic arch

preductal region of aortic arch definition Area of aorta proximal to the ductus arteriosus.
preductal region of aortic arch has obo namespace uberon
preductal region of aortic arch has exact synonym preligamental region of aortic arch { database cross reference=FMA:3774 }
preductal region of aortic arch SubClassOf part of some descending trunk of arch of aorta
preductal region of aortic arch id UBERON:0016923
preductal region of aortic arch database cross reference FMA:3774
preductal region of aortic arch SubClassOf organ segment
preductal region of aortic arch label preductal region of aortic arch
preductal region of aortic arch SubClassOf mixed endoderm/mesoderm-derived structure
preductal region of aortic arch SubClassOf structure with developmental contribution from neural crest
preductal region of aortic arch database cross reference http://www.snomedbrowser.com/Codes/Details/197773005

New Class : postductal region of aortic arch

postductal region of aortic arch definition Area of aorta distal to the ductus arteriosus.
postductal region of aortic arch has obo namespace uberon
postductal region of aortic arch has exact synonym postligamental region of aortic arch { database cross reference=FMA:3776 }
postductal region of aortic arch SubClassOf mixed endoderm/mesoderm-derived structure
postductal region of aortic arch database cross reference FMA:3776
postductal region of aortic arch SubClassOf structure with developmental contribution from neural crest
postductal region of aortic arch SubClassOf part of some descending trunk of arch of aorta
postductal region of aortic arch label postductal region of aortic arch
postductal region of aortic arch id UBERON:0016924
postductal region of aortic arch SubClassOf organ segment
postductal region of aortic arch database cross reference http://www.snomedbrowser.com/Codes/Details/197852003

New Class : juxtaductal region of aortic arch

juxtaductal region of aortic arch SubClassOf part of some descending trunk of arch of aorta
juxtaductal region of aortic arch definition Area of aorta at the area of insertion to the ductus arteriosus.
juxtaductal region of aortic arch has exact synonym juxtaligamental region of aortic arch { database cross reference=FMA:3778 }
juxtaductal region of aortic arch has obo namespace uberon
juxtaductal region of aortic arch has related synonym aortic isthmus
juxtaductal region of aortic arch SubClassOf mixed endoderm/mesoderm-derived structure
juxtaductal region of aortic arch id UBERON:0016925
juxtaductal region of aortic arch database cross reference http://www.snomedbrowser.com/Codes/Details/197932000
juxtaductal region of aortic arch database cross reference http://www.snomedbrowser.com/Codes/Details/197677000
juxtaductal region of aortic arch label juxtaductal region of aortic arch
juxtaductal region of aortic arch SubClassOf organ segment
juxtaductal region of aortic arch database cross reference FMA:3778
juxtaductal region of aortic arch SubClassOf structure with developmental contribution from neural crest
juxtaductal region of aortic arch database cross reference FMA:3771

New Class : mucus body coating

mucus body coating label mucus body coating
mucus body coating definition A coating of mucus that is produced by the skin and covers all or most of the body of an animal. { database cross reference=UBERON:cjm }
mucus body coating database cross reference BTO:0005082
mucus body coating has obo namespace uberon
mucus body coating has related synonym mucous body coating
mucus body coating SubClassOf surrounds some multi-cellular organism
mucus body coating SubClassOf skin mucus
mucus body coating id UBERON:0016926
mucus body coating function notes The epidermal mucus of fish regulates swimming speed by controlling the hydrodynamic resistance of the skin surface. The mucus is also presumed to serve as a defence against pathogenic organisms and is intimately associated with osmoregulation. [BTO:0005082]

New Class : mucus cocoon

mucus cocoon SubClassOf surrounds some multi-cellular organism
mucus cocoon id UBERON:0016927
mucus cocoon label mucus cocoon
mucus cocoon has related synonym mucous cocoon
mucus cocoon definition A mucous covering produced nocturnally by some fish that is used to envelope the whole animal. { database cross reference=http://www.ncbi.nlm.nih.gov/pubmed/21084337 }
mucus cocoon has obo namespace uberon
mucus cocoon SubClassOf mucus

New Class : metaphysis of fibula

metaphysis of fibula label metaphysis of fibula
metaphysis of fibula SubClassOf mesoderm-derived structure
metaphysis of fibula SubClassOf metaphysis
metaphysis of fibula has obo namespace uberon
metaphysis of fibula has exact synonym fibular metaphysis
metaphysis of fibula SubClassOf part of some fibula
metaphysis of fibula definition A metaphysis that is part of a fibula. { database cross reference=UBERON:nv }
metaphysis of fibula database cross reference FMA:33745
metaphysis of fibula has exact synonym fibula metaphysis { database cross reference=FMA:33745 }
metaphysis of fibula id UBERON:0016928
metaphysis of fibula EquivalentTo metaphysis and part of some fibula

New Class : lingual cusp of tooth

lingual cusp of tooth has exact synonym lingual cusp { database cross reference=FMA:56490 }
lingual cusp of tooth SubClassOf cusp of tooth
lingual cusp of tooth id UBERON:0016929
lingual cusp of tooth database cross reference http://www.snomedbrowser.com/Codes/Details/245720006
lingual cusp of tooth label lingual cusp of tooth
lingual cusp of tooth has alternative id UBERONTEMP:0ea3066e-0c22-417b-8ac4-91c2aacba792
lingual cusp of tooth database cross reference FMA:56490
lingual cusp of tooth has exact synonym cuspis lingualis { database cross reference=FMA:TA , has synonym type=latin term }
lingual cusp of tooth has obo namespace uberon

New Class : descending trunk of arch of aorta

descending trunk of arch of aorta has exact synonym descending trunk of aortic arch { database cross reference=FMA:13082 }
descending trunk of arch of aorta has obo namespace uberon
descending trunk of arch of aorta SubClassOf organ segment
descending trunk of arch of aorta SubClassOf structure with developmental contribution from neural crest
descending trunk of arch of aorta has exact synonym descending aortic arch { database cross reference=HP:0012305 }
descending trunk of arch of aorta SubClassOf part of some arch of aorta
descending trunk of arch of aorta SubClassOf mixed endoderm/mesoderm-derived structure
descending trunk of arch of aorta label descending trunk of arch of aorta
descending trunk of arch of aorta id UBERON:0016920
descending trunk of arch of aorta database cross reference FMA:13082
descending trunk of arch of aorta has exact synonym descending limb of arch of aorta { database cross reference=FMA:13082 }

New Class : lamina lucida

lamina lucida SubClassOf acellular membrane
lamina lucida label lamina lucida
lamina lucida has obo namespace uberon
lamina lucida has exact synonym lamina rara { database cross reference=FMA:62921 }
lamina lucida has exact synonym electron-lucent layer of basal lamina of connective tissue { database cross reference=FMA:62921 }
lamina lucida database cross reference http://ncicb.nci.nih.gov/xml/owl/EVS/Lamina_Lucida
lamina lucida database cross reference FMA:62921
lamina lucida database cross reference http://linkedlifedata.com/resource/umls/id/C1167355
lamina lucida SubClassOf part of some basal lamina of epithelium
lamina lucida id UBERON:0016914

New Class : vermilion

vermilion SubClassOf ectoderm-derived structure
vermilion SubClassOf part of some mouth
vermilion label vermilion
vermilion id UBERON:0016915
vermilion database cross reference FMA:59824
vermilion has exact synonym vermilion border of lip
vermilion SubClassOf organism subdivision
vermilion has exact synonym vermilion of lip
vermilion database cross reference http://www.snomedbrowser.com/Codes/Details/362086008
vermilion has obo namespace uberon

New Class : frenulum of upper lip

frenulum of upper lip database cross reference FMA:59821
frenulum of upper lip id UBERON:0016912
frenulum of upper lip database cross reference http://www.snomedbrowser.com/Codes/Details/264488001
frenulum of upper lip EquivalentTo frenulum of lip and part of some upper lip
frenulum of upper lip has exact synonym frenulum labii superioris { has synonym type=latin term }
frenulum of upper lip SubClassOf part of some mucosa of upper lip
frenulum of upper lip SubClassOf frenulum of lip
frenulum of upper lip label frenulum of upper lip
frenulum of upper lip SubClassOf mucosa of upper lip
frenulum of upper lip has obo namespace uberon
frenulum of upper lip has exact synonym upper lip frenulum { database cross reference=FMA:59821 }
frenulum of upper lip SubClassOf part of some upper lip

New Class : frenulum of lower lip

frenulum of lower lip id UBERON:0016913
frenulum of lower lip database cross reference http://www.snomedbrowser.com/Codes/Details/277191003
frenulum of lower lip has related synonym frenulum labii inferioris { database cross reference=http://en.wikipedia.org/wiki/Frenulum_of_lower_lip , has synonym type=latin term }
frenulum of lower lip has exact synonym lower lip frenulum { database cross reference=FMA:59822 }
frenulum of lower lip label frenulum of lower lip
frenulum of lower lip database cross reference FMA:59822
frenulum of lower lip has obo namespace uberon
frenulum of lower lip has related synonym f. labii inferioris { database cross reference=http://en.wikipedia.org/wiki/Frenulum_of_lower_lip , has synonym type=latin term }
frenulum of lower lip database cross reference http://en.wikipedia.org/wiki/Frenulum_of_lower_lip
frenulum of lower lip SubClassOf part of some mucosa of lower lip
frenulum of lower lip SubClassOf part of some lower lip
frenulum of lower lip has exact synonym frenulum labii inferioris
frenulum of lower lip SubClassOf mucosa of lower lip
frenulum of lower lip EquivalentTo frenulum of lip and part of some lower lip
frenulum of lower lip SubClassOf frenulum of lip

New Class : upper vermilion

upper vermilion has obo namespace uberon
upper vermilion has exact synonym vermilion of upper lip { database cross reference=FMA:59827 }
upper vermilion SubClassOf vermilion
upper vermilion database cross reference FMA:59827
upper vermilion SubClassOf structure with developmental contribution from neural crest
upper vermilion id UBERON:0016918
upper vermilion database cross reference http://www.snomedbrowser.com/Codes/Details/245799004
upper vermilion SubClassOf endoderm-derived structure
upper vermilion EquivalentTo vermilion and part of some upper lip
upper vermilion SubClassOf part of some upper lip
upper vermilion has exact synonym vermilion border of upper lip
upper vermilion label upper vermilion

New Class : lower vermilion

lower vermilion has obo namespace uberon
lower vermilion id UBERON:0016919
lower vermilion SubClassOf vermilion
lower vermilion has exact synonym vermilion of lower lip { database cross reference=FMA:59828 }
lower vermilion EquivalentTo vermilion and part of some lower lip
lower vermilion SubClassOf endoderm-derived structure
lower vermilion database cross reference FMA:59828
lower vermilion label lower vermilion
lower vermilion database cross reference http://www.snomedbrowser.com/Codes/Details/245800000
lower vermilion has exact synonym vermilion border of lower lip
lower vermilion SubClassOf part of some lower lip
lower vermilion SubClassOf structure with developmental contribution from neural crest

New Class : frenulum of lip

frenulum of lip SubClassOf integumentary system layer
frenulum of lip database cross reference FMA:59820
frenulum of lip id UBERON:0016910
frenulum of lip has exact synonym frenulum labii
frenulum of lip label frenulum of lip
frenulum of lip has exact synonym lip frenulum { database cross reference=FMA:59820 }
frenulum of lip SubClassOf part of some lip
frenulum of lip has obo namespace uberon
frenulum of lip SubClassOf mouth mucosa
frenulum of lip database cross reference http://www.snomedbrowser.com/Codes/Details/264053009

Changed Class objects: 644

Changes for: levator mandibulae externus

Deleted
- - levator mandibulae externus SubClassOf is innervated by some mandibular nerve
Added
- + levator mandibulae externus SubClassOf innervated by some mandibular nerve

Changes for: levator mandibulae articularis

Deleted
- - levator mandibulae articularis SubClassOf is innervated by some mandibular nerve
Added
- + levator mandibulae articularis SubClassOf innervated by some mandibular nerve

Changes for: levator mandibulae lateralis

Deleted
- - levator mandibulae lateralis SubClassOf is innervated by some mandibular nerve
Added
- + levator mandibulae lateralis SubClassOf innervated by some mandibular nerve

Changes for: levator mandibulae longus

Deleted
- - levator mandibulae longus SubClassOf is innervated by some ramus posterior profundus of V3
Added
- + levator mandibulae longus SubClassOf innervated by some ramus posterior profundus of V3

Changes for: tonsil germinal center

Deleted
- - tonsil germinal center comment Editor note: consider adding related terms, e.g. secondary lymphoid tissue of tonsil
Added
- + tonsil germinal center editor note consider adding related terms, e.g. secondary lymphoid tissue of tonsil

Changes for: anatomical conduit space

Deleted
- - anatomical conduit space SubClassOf ObjectMinCardinality( connects anatomical space ) and ObjectMaxCardinality( connects anatomical space )
Added
- + anatomical conduit space SubClassOf ObjectMinCardinality( connects anatomical space ) and ObjectMaxCardinality( connects anatomical space )

Changes for: subarcualis rectus I

Deleted
- - subarcualis rectus I SubClassOf is innervated by some ramus muscularis of glossopharyngeus nerve
Added
- + subarcualis rectus I SubClassOf innervated by some ramus muscularis of glossopharyngeus nerve

Changes for: trunk maxillary-mandibularis

Deleted
- - trunk maxillary-mandibularis SubClassOf branch of some trigeminal nerve
Added
- + trunk maxillary-mandibularis SubClassOf branching part of some trigeminal nerve

Changes for: anatomical line between inner canthi

Deleted
- - anatomical line between inner canthi EquivalentTo anatomical line and part of some face and connects some inner canthus of right eye and connects some inner canthus of left eye
- - anatomical line between inner canthi SubClassOf connects some inner canthus of left eye
- - anatomical line between inner canthi SubClassOf connects some inner canthus of right eye
Added
- + anatomical line between inner canthi EquivalentTo anatomical line and part of some face and connects some inner canthus of right eye and connects some inner canthus of left eye
- + anatomical line between inner canthi SubClassOf connects some inner canthus of left eye
- + anatomical line between inner canthi SubClassOf connects some inner canthus of right eye

Changes for: bone of upper jaw

Deleted
- - bone of upper jaw comment Editor notes: Do not manually classify under here - bones are automatically classified
Added
- + bone of upper jaw editor note Do not manually classify under here - bones are automatically classified

Changes for: dentary tooth

Deleted
- - dentary tooth comment Editor notes: Note that we treat dentary tooth and mandibular tooth as equivalent
Added
- + dentary tooth editor note Note that we treat dentary tooth and mandibular tooth as equivalent

Changes for: cell condensation

Deleted
- - cell condensation comment Editor notes: consider obsoleting, coordinate with VSAO
Added
- + cell condensation editor note consider obsoleting, coordinate with VSAO

Changes for: non-mineralized cartilage tissue

Deleted
- - non-mineralized cartilage tissue comment Editor notes: add developmental relationships; add disjointness axiom
Added
- + non-mineralized cartilage tissue editor note add developmental relationships; add disjointness axiom

Changes for: subdivision of organism along main body axis

Deleted
- - subdivision of organism along main body axis comment Editor notes: Ideally this would be disjoint with analagous class for appendicular axes, but currently ‘appendages’ like antennae, horns cause a problem
Added
- + subdivision of organism along main body axis editor note Ideally this would be disjoint with analagous class for appendicular axes, but currently ‘appendages’ like antennae, horns cause a problem

Changes for: thyrohyoid bone

Deleted
- - thyrohyoid bone SubClassOf connects some basihyal bone
- - thyrohyoid bone SubClassOf connects some horn of thyroid cartilage
Added
- + thyrohyoid bone SubClassOf connects some basihyal bone
- + thyrohyoid bone SubClassOf connects some horn of thyroid cartilage

Changes for: thyrohyoid cartilage

Deleted
- - thyrohyoid cartilage SubClassOf connects some horn of thyroid cartilage
- - thyrohyoid cartilage SubClassOf connects some thyrohyoid bone
Added
- + thyrohyoid cartilage SubClassOf connects some horn of thyroid cartilage
- + thyrohyoid cartilage SubClassOf connects some thyrohyoid bone

Changes for: tympanohyoid cartilage

Deleted
- - tympanohyoid cartilage SubClassOf connects some hyoid bone
- - tympanohyoid cartilage SubClassOf connects some styloid process of temporal bone
Added
- + tympanohyoid cartilage SubClassOf connects some hyoid bone
- + tympanohyoid cartilage SubClassOf connects some styloid process of temporal bone

Changes for: external cervical os

Deleted
- - external cervical os SubClassOf connects some uterine cervix
- - external cervical os SubClassOf connects some vagina
Added
- + external cervical os SubClassOf connects some uterine cervix
- + external cervical os SubClassOf connects some vagina

Changes for: intermammary line

Deleted
- - intermammary line EquivalentTo anatomical line and connects some left nipple
- - intermammary line SubClassOf connects some left nipple
Added
- + intermammary line EquivalentTo anatomical line and connects some left nipple
- + intermammary line SubClassOf connects some left nipple

Changes for: utriculosaccular duct

Deleted
- - utriculosaccular duct EquivalentTo tube and connects some utricle of membranous labyrinth and connects some saccule of membranous labyrinth and connects some endolymphatic duct
- - utriculosaccular duct SubClassOf connects some endolymphatic duct
- - utriculosaccular duct SubClassOf connects some saccule of membranous labyrinth
- - utriculosaccular duct SubClassOf connects some utricle of membranous labyrinth
Added
- + utriculosaccular duct EquivalentTo tube and connects some utricle of membranous labyrinth and connects some saccule of membranous labyrinth and connects some endolymphatic duct
- + utriculosaccular duct SubClassOf connects some endolymphatic duct
- + utriculosaccular duct SubClassOf connects some saccule of membranous labyrinth
- + utriculosaccular duct SubClassOf connects some utricle of membranous labyrinth

Changes for: genital swelling

Deleted
- - genital swelling comment Editor notes: todo - add parthood relationships to tubercles
Added
- + genital swelling editor note todo - add parthood relationships to tubercles

Changes for: pterygoideus

Deleted
- - pterygoideus SubClassOf is innervated by some trigeminal nerve
Added
- + pterygoideus SubClassOf innervated by some trigeminal nerve

Changes for: midcarpal joint

Deleted
- - midcarpal joint SubClassOf connects some distal carpal bone
- - midcarpal joint SubClassOf connects some proximal carpal bone
Added
- + midcarpal joint SubClassOf connects some distal carpal bone
- + midcarpal joint SubClassOf connects some proximal carpal bone

Changes for: pisiform joint

Deleted
- - pisiform joint EquivalentTo intercarpal joint and connects some pisiform and connects some ulnare
- - pisiform joint SubClassOf connects some pisiform
- - pisiform joint SubClassOf connects some ulnare
Added
- + pisiform joint EquivalentTo intercarpal joint and connects some pisiform and connects some ulnare
- + pisiform joint SubClassOf connects some pisiform
- + pisiform joint SubClassOf connects some ulnare

Changes for: ramus auricularis of the vagus nerve

Deleted
- - ramus auricularis of the vagus nerve SubClassOf innervates some tympanic ring
Added
- + ramus auricularis of the vagus nerve SubClassOf innervates some tympanic ring

Changes for: nasomaxillary suture

Deleted
- - nasomaxillary suture EquivalentTo cranial suture and connects some nasal bone and connects some maxilla
- - nasomaxillary suture SubClassOf connects some maxilla
- - nasomaxillary suture SubClassOf connects some nasal bone
Added
- + nasomaxillary suture EquivalentTo cranial suture and connects some nasal bone and connects some maxilla
- + nasomaxillary suture SubClassOf connects some maxilla
- + nasomaxillary suture SubClassOf connects some nasal bone

Changes for: levator quadrati

Deleted
- - levator quadrati SubClassOf is innervated by some trigeminal nerve
Added
- + levator quadrati SubClassOf innervated by some trigeminal nerve

Changes for: ramus muscularis of glossopharyngeus nerve

Deleted
- - ramus muscularis of glossopharyngeus nerve SubClassOf innervates some subarcualis rectus I
Added
- + ramus muscularis of glossopharyngeus nerve SubClassOf innervates some subarcualis rectus I

Changes for: ramus muscularis of vagus nerve

Deleted
- - ramus muscularis of vagus nerve SubClassOf innervates some subarcualis rectus I
Added
- + ramus muscularis of vagus nerve SubClassOf innervates some subarcualis rectus I

Changes for: laryngeus ventralis

Deleted
- - laryngeus ventralis SubClassOf innervates some heart
- - laryngeus ventralis SubClassOf innervates some lung
- - laryngeus ventralis SubClassOf innervates some stomach
Added
- + laryngeus ventralis SubClassOf innervates some heart
- + laryngeus ventralis SubClassOf innervates some lung
- + laryngeus ventralis SubClassOf innervates some stomach

Changes for: perilymphatic channel

Deleted
- - perilymphatic channel comment Editor notes: relationship to FMA class unclear
Added
- + perilymphatic channel editor note relationship to FMA class unclear

Changes for: umbilical smooth muscle

Added
- + umbilical smooth muscle SubClassOf extraembryonic tissue

Changes for: gastroduodenal junction

Deleted
- - gastroduodenal junction EquivalentTo anatomical junction and connects some stomach and connects some duodenum
- - gastroduodenal junction SubClassOf connects some duodenum
- - gastroduodenal junction SubClassOf connects some stomach
Added
- + gastroduodenal junction EquivalentTo anatomical junction and connects some stomach and connects some duodenum
- + gastroduodenal junction SubClassOf connects some duodenum
- + gastroduodenal junction SubClassOf connects some stomach

Changes for: corpus spongiosum of penis

Deleted
- - corpus spongiosum of penis comment Function notes: The function of the corpus spongiosum in erection is to prevent the urethra from pinching closed, thereby maintaining the urethra as a viable channel for ejaculation. To do this, the corpus spongiosum remains pliable during erection while the corpora cavernosum penis becomes engorged with blood.[WP]
Added
- + corpus spongiosum of penis function notes The function of the corpus spongiosum in erection is to prevent the urethra from pinching closed, thereby maintaining the urethra as a viable channel for ejaculation. To do this, the corpus spongiosum remains pliable during erection while the corpora cavernosum penis becomes engorged with blood.[WP]

Changes for: lesser tubercle of humerus

Deleted
- - lesser tubercle of humerus SubClassOf skeletal element projection
- - lesser tubercle of humerus SubClassOf tubercle
Added
- + lesser tubercle of humerus SubClassOf bony tubercle

Changes for: greater tubercle of humerus

Deleted
- - greater tubercle of humerus SubClassOf skeletal element projection
- - greater tubercle of humerus SubClassOf tubercle
Added
- + greater tubercle of humerus SubClassOf bony tubercle

Changes for: optic tract

Deleted
- - optic tract comment editor note: relationships need checking by expert. NIF and ZFA both state part of diencepahalon; MA says part of optic nerve II. in uberon, CNS and PNS are spatially disjoint, and axon tracts are part of the CNS so we make the relationship to CNII ‘continuous_with’
Added
- + optic tract editor note relationships need checking by expert. NIF and ZFA both state part of diencepahalon; MA says part of optic nerve II. in uberon, CNS and PNS are spatially disjoint, and axon tracts are part of the CNS so we make the relationship to CNII ‘continuous_with’

Changes for: prostatic utricle

Deleted
- - prostatic utricle comment Editor notes: add df relations. Check mesopnephric duct
Added
- + prostatic utricle editor note add df relations. Check mesopnephric duct

Changes for: habenular commissure

Deleted
- - habenular commissure EquivalentTo nervous system commissure and connects some habenular nucleus
- - habenular commissure SubClassOf connects some habenular nucleus
Added
- + habenular commissure EquivalentTo nervous system commissure and connects some habenular nucleus
- + habenular commissure SubClassOf connects some habenular nucleus

Changes for: red nucleus

Deleted
- - red nucleus comment Function notes: in animals without a significant corticospinal tract, gait is mainly controlled by the red nucleus.
Added
- + red nucleus function notes in animals without a significant corticospinal tract, gait is mainly controlled by the red nucleus.

Changes for: patellofemoral joint

Deleted
- - patellofemoral joint SubClassOf connects some femur
- - patellofemoral joint SubClassOf connects some patella
Added
- + patellofemoral joint SubClassOf connects some femur
- + patellofemoral joint SubClassOf connects some patella

Changes for: nasal suture

Deleted
- - nasal suture EquivalentTo facial suture and connects some nasal bone
- - nasal suture SubClassOf connects some nasal bone
Added
- + nasal suture EquivalentTo facial suture and connects some nasal bone
- + nasal suture SubClassOf connects some nasal bone

Changes for: spheno-occipital synchondrosis

Deleted
- - spheno-occipital synchondrosis EquivalentTo cranial synchondrosis and connects some basioccipital bone and connects some basisphenoid bone
- - spheno-occipital synchondrosis SubClassOf connects some basioccipital bone
- - spheno-occipital synchondrosis SubClassOf connects some basisphenoid bone
Added
- + spheno-occipital synchondrosis EquivalentTo cranial synchondrosis and connects some basioccipital bone and connects some basisphenoid bone
- + spheno-occipital synchondrosis SubClassOf connects some basioccipital bone
- + spheno-occipital synchondrosis SubClassOf connects some basisphenoid bone

Changes for: quadrate-articular joint

Deleted
- - quadrate-articular joint EquivalentTo skeletal joint and connects some articular/anguloarticular and connects some quadrate bone
- - quadrate-articular joint SubClassOf connects some articular/anguloarticular
- - quadrate-articular joint SubClassOf connects some quadrate bone
Added
- + quadrate-articular joint EquivalentTo skeletal joint and connects some articular/anguloarticular and connects some quadrate bone
- + quadrate-articular joint SubClassOf connects some articular/anguloarticular
- + quadrate-articular joint SubClassOf connects some quadrate bone

Changes for: jaw joint

Deleted
- - jaw joint EquivalentTo skeletal joint and connects some skeleton of upper jaw and connects some skeleton of lower jaw
- - jaw joint SubClassOf connects some skeleton of lower jaw
- - jaw joint SubClassOf connects some skeleton of upper jaw
Added
- + jaw joint EquivalentTo skeletal joint and connects some skeleton of upper jaw and connects some skeleton of lower jaw
- + jaw joint SubClassOf connects some skeleton of lower jaw
- + jaw joint SubClassOf connects some skeleton of upper jaw

Changes for: mucosa-associated lymphoid tissue

Deleted
- - mucosa-associated lymphoid tissue comment Editor notes: todo - add part relationships to specific layers
Added
- + mucosa-associated lymphoid tissue editor note todo - add part relationships to specific layers

Changes for: gut-associated lymphoid tissue

Deleted
- - gut-associated lymphoid tissue comment Editor notes: phylogenetic relationships to be added. Taxon notes: guts of jawless fish contains cells with lymphocyte-like morphology (Mayer 2002).
Added
- + gut-associated lymphoid tissue comment Taxon notes: guts of jawless fish contains cells with lymphocyte-like morphology (Mayer 2002).
- + gut-associated lymphoid tissue editor note phylogenetic relationships to be added

Changes for: sternocostal joint

Deleted
- - sternocostal joint SubClassOf connects some sternum
Added
- + sternocostal joint SubClassOf connects some sternum

Changes for: synovial joint of pectoral girdle

Deleted
- - synovial joint of pectoral girdle SubClassOf connects some pectoral girdle bone
Added
- + synovial joint of pectoral girdle SubClassOf connects some pectoral girdle bone
- + synovial joint of pectoral girdle database cross reference http://www.snomedbrowser.com/Codes/Details/303080001
- + synovial joint of pectoral girdle has exact synonym joint of shoulder girdle

Changes for: synovial joint of pelvic girdle

Deleted
- - synovial joint of pelvic girdle SubClassOf connects some pelvic girdle bone/zone
Added
- + synovial joint of pelvic girdle SubClassOf connects some pelvic girdle bone/zone

Changes for: placenta

Added
- + placenta SubClassOf part of some entire extraembryonic component

Changes for: tibiofibular joint

Deleted
- - tibiofibular joint EquivalentTo skeletal joint and part of some hindlimb zeugopod and connects some tibia and connects some fibula
- - tibiofibular joint SubClassOf connects some fibula
- - tibiofibular joint SubClassOf connects some tibia
- - tibiofibular joint comment Editor notes: we include location as part of the logical definition to prevent accidental classification of ankle joints as tibiofibular joints
Added
- + tibiofibular joint EquivalentTo skeletal joint and part of some hindlimb zeugopod and connects some tibia and connects some fibula
- + tibiofibular joint SubClassOf connects some fibula
- + tibiofibular joint SubClassOf connects some tibia
- + tibiofibular joint editor note we include location as part of the logical definition to prevent accidental classification of ankle joints as tibiofibular joints

Changes for: humeroradial joint

Deleted
- - humeroradial joint EquivalentTo skeletal joint and connects some humerus and connects some radius bone
- - humeroradial joint SubClassOf connects some humerus
- - humeroradial joint SubClassOf connects some radius bone
Added
- + humeroradial joint EquivalentTo skeletal joint and connects some humerus and connects some radius bone
- + humeroradial joint SubClassOf connects some humerus
- + humeroradial joint SubClassOf connects some radius bone

Changes for: inferior tibiofibular joint

Deleted
- - inferior tibiofibular joint SubClassOf connects some distal epiphysis of fibula
- - inferior tibiofibular joint SubClassOf connects some tibia
Added
- + inferior tibiofibular joint SubClassOf connects some distal epiphysis of fibula
- + inferior tibiofibular joint SubClassOf connects some tibia

Changes for: humeroulnar joint

Deleted
- - humeroulnar joint EquivalentTo skeletal joint and connects some humerus and connects some ulna
- - humeroulnar joint SubClassOf connects some humerus
- - humeroulnar joint SubClassOf connects some ulna
Added
- + humeroulnar joint EquivalentTo skeletal joint and connects some humerus and connects some ulna
- + humeroulnar joint SubClassOf connects some humerus
- + humeroulnar joint SubClassOf connects some ulna

Changes for: carpometacarpal joint

Deleted
- - carpometacarpal joint EquivalentTo skeletal joint and connects some carpal bone and connects some metacarpal bone
- - carpometacarpal joint SubClassOf connects some carpal bone
- - carpometacarpal joint SubClassOf connects some metacarpal bone
Added
- + carpometacarpal joint EquivalentTo skeletal joint and connects some carpal bone and connects some metacarpal bone
- + carpometacarpal joint SubClassOf connects some carpal bone
- + carpometacarpal joint SubClassOf connects some metacarpal bone

Changes for: superior tibiofibular joint

Deleted
- - superior tibiofibular joint EquivalentTo tibiofibular joint and connects some proximal epiphysis of fibula and connects some lateral condyle of femur
- - superior tibiofibular joint SubClassOf connects some lateral condyle of femur
- - superior tibiofibular joint SubClassOf connects some proximal epiphysis of fibula
Added
- + superior tibiofibular joint EquivalentTo tibiofibular joint and connects some proximal epiphysis of fibula and connects some lateral condyle of femur
- + superior tibiofibular joint SubClassOf connects some lateral condyle of femur
- + superior tibiofibular joint SubClassOf connects some proximal epiphysis of fibula

Changes for: tarsometatarsal joint

Deleted
- - tarsometatarsal joint EquivalentTo skeletal joint and connects some tarsal bone and connects some metatarsal bone
- - tarsometatarsal joint SubClassOf connects some metatarsal bone
- - tarsometatarsal joint SubClassOf connects some tarsal bone
Added
- + tarsometatarsal joint EquivalentTo skeletal joint and connects some tarsal bone and connects some metatarsal bone
- + tarsometatarsal joint SubClassOf connects some metatarsal bone
- + tarsometatarsal joint SubClassOf connects some tarsal bone

Changes for: capillary

Deleted
- - capillary EquivalentTo blood vessel and connects some venule and connects some arteriole
- - capillary SubClassOf connects some arteriole
- - capillary SubClassOf connects some venule
Added
- + capillary EquivalentTo blood vessel and connects some venule and connects some arteriole
- + capillary SubClassOf connects some arteriole
- + capillary SubClassOf connects some venule

Changes for: cricothyroid joint

Deleted
- - cricothyroid joint EquivalentTo skeletal joint and connects some thyroid cartilage and connects some cricoid cartilage
- - cricothyroid joint SubClassOf connects some cricoid cartilage
- - cricothyroid joint SubClassOf connects some thyroid cartilage
Added
- + cricothyroid joint EquivalentTo skeletal joint and connects some thyroid cartilage and connects some cricoid cartilage
- + cricothyroid joint SubClassOf connects some cricoid cartilage
- + cricothyroid joint SubClassOf connects some thyroid cartilage

Changes for: laryngeal joint

Deleted
- - laryngeal joint EquivalentTo skeletal joint and connects some laryngeal cartilage
- - laryngeal joint SubClassOf connects some laryngeal cartilage
Added
- + laryngeal joint EquivalentTo skeletal joint and connects some laryngeal cartilage
- + laryngeal joint SubClassOf connects some laryngeal cartilage

Changes for: xiphisternal joint

Deleted
- - xiphisternal joint EquivalentTo skeletal joint and connects some xiphoid process and connects some body of sternum
- - xiphisternal joint SubClassOf connects some body of sternum
- - xiphisternal joint SubClassOf connects some xiphoid process
Added
- + xiphisternal joint EquivalentTo skeletal joint and connects some xiphoid process and connects some body of sternum
- + xiphisternal joint SubClassOf connects some body of sternum
- + xiphisternal joint SubClassOf connects some xiphoid process

Changes for: stifle joint

Deleted
- - stifle joint SubClassOf connects some femur
- - stifle joint SubClassOf connects some patella
- - stifle joint SubClassOf connects some tibia
Added
- + stifle joint SubClassOf connects some femur
- + stifle joint SubClassOf connects some patella
- + stifle joint SubClassOf connects some tibia

Changes for: cricoarytenoid joint

Deleted
- - cricoarytenoid joint EquivalentTo skeletal joint and connects some arytenoid cartilage and connects some cricoid cartilage
- - cricoarytenoid joint SubClassOf connects some arytenoid cartilage
- - cricoarytenoid joint SubClassOf connects some cricoid cartilage
Added
- + cricoarytenoid joint EquivalentTo skeletal joint and connects some arytenoid cartilage and connects some cricoid cartilage
- + cricoarytenoid joint SubClassOf connects some arytenoid cartilage
- + cricoarytenoid joint SubClassOf connects some cricoid cartilage

Changes for: intercarpal joint

Deleted
- - intercarpal joint EquivalentTo skeletal joint and ObjectMinCardinality( connects carpal bone ) and ObjectMaxCardinality( connects carpal bone )
- - intercarpal joint SubClassOf connects some carpal bone
Added
- + intercarpal joint EquivalentTo skeletal joint and ObjectMinCardinality( connects carpal bone ) and ObjectMaxCardinality( connects carpal bone )
- + intercarpal joint SubClassOf connects some carpal bone

Changes for: intermetacarpal joint

Deleted
- - intermetacarpal joint EquivalentTo skeletal joint and ObjectMinCardinality( connects metacarpal bone ) and ObjectMaxCardinality( connects metacarpal bone )
- - intermetacarpal joint SubClassOf connects some metacarpal bone
Added
- + intermetacarpal joint EquivalentTo skeletal joint and ObjectMinCardinality( connects metacarpal bone ) and ObjectMaxCardinality( connects metacarpal bone )
- + intermetacarpal joint SubClassOf connects some metacarpal bone

Changes for: intermetatarsal joint

Deleted
- - intermetatarsal joint EquivalentTo skeletal joint and ObjectMinCardinality( connects metatarsal bone ) and ObjectMaxCardinality( connects metatarsal bone )
- - intermetatarsal joint SubClassOf connects some metatarsal bone
Added
- + intermetatarsal joint EquivalentTo skeletal joint and ObjectMinCardinality( connects metatarsal bone ) and ObjectMaxCardinality( connects metatarsal bone )
- + intermetatarsal joint SubClassOf connects some metatarsal bone

Changes for: sacrococcygeal symphysis

Deleted
- - sacrococcygeal symphysis EquivalentTo skeletal joint and connects some coccyx and connects some sacrum
- - sacrococcygeal symphysis SubClassOf connects some coccyx
- - sacrococcygeal symphysis SubClassOf connects some sacrum
Added
- + sacrococcygeal symphysis EquivalentTo skeletal joint and connects some coccyx and connects some sacrum
- + sacrococcygeal symphysis SubClassOf connects some coccyx
- + sacrococcygeal symphysis SubClassOf connects some sacrum

Changes for: pubo-ischium

Deleted
- - pubo-ischium SubClassOf has fused element some ischium
- - pubo-ischium SubClassOf has fused element some pubis
Added
- + pubo-ischium SubClassOf has fused element some ischium
- + pubo-ischium SubClassOf has fused element some pubis

Changes for: retromolar triangle

Deleted
- - retromolar triangle comment Editor notes: requires verification
Added
- + retromolar triangle editor note requires verification

Changes for: bone of jaw

Deleted
- - bone of jaw comment Editor notes: Do not manually classify under here - bones are automatically classified
Added
- + bone of jaw editor note Do not manually classify under here - bones are automatically classified

Changes for: lateral olfactory tract

Deleted
- - lateral olfactory tract comment Editor notes: We follow neurolex and use ‘tract’ rather than ‘stria’ as the primary label. We make this a subtype of olfactory tract. Currently this groups teleost and mammalian structures by the same name, but this may be a false grouping. For example, in zebrafish, the difference between medial and lateral depends on the region of telencephalon (dorsal or ventral). Taxon notes: In mammals the fibers of the dorsal lateral olfactory tract either pass under the accessory olfactory formation, or they penetrate through it separating the internal granule cells from the output cells.[PMID:7437895]
Added
- + lateral olfactory tract editor note We follow neurolex and use ‘tract’ rather than ‘stria’ as the primary label. We make this a subtype of olfactory tract. Currently this groups teleost and mammalian structures by the same name, but this may be a false grouping. For example, in zebrafish, the difference between medial and lateral depends on the region of telencephalon (dorsal or ventral). Taxon notes: In mammals the fibers of the dorsal lateral olfactory tract either pass under the accessory olfactory formation, or they penetrate through it separating the internal granule cells from the output cells.[PMID:7437895]

Changes for: ora serrata of retina

Deleted
- - ora serrata of retina SubClassOf connects some ciliary body
- - ora serrata of retina SubClassOf connects some retina
Added
- + ora serrata of retina SubClassOf connects some ciliary body
- + ora serrata of retina SubClassOf connects some retina

Changes for: ductus reuniens

Deleted
- - ductus reuniens SubClassOf connects some cochlear duct of membranous labyrinth
- - ductus reuniens SubClassOf connects some saccule of membranous labyrinth
Added
- + ductus reuniens SubClassOf connects some cochlear duct of membranous labyrinth
- + ductus reuniens SubClassOf connects some saccule of membranous labyrinth

Changes for: posterior semicircular canal

Deleted
- - posterior semicircular canal comment Editor notes: verify AAO
Added
- + posterior semicircular canal editor note verify AAO

Changes for: carpometacarpal joint of digit 1

Deleted
- - carpometacarpal joint of digit 1 EquivalentTo carpometacarpal joint and connects some metacarpal bone of digit 1
- - carpometacarpal joint of digit 1 SubClassOf connects some metacarpal bone of digit 1
Added
- + carpometacarpal joint of digit 1 EquivalentTo carpometacarpal joint and connects some metacarpal bone of digit 1
- + carpometacarpal joint of digit 1 SubClassOf connects some metacarpal bone of digit 1

Changes for: caudal-sacral region of vertebral column

Added
- + caudal-sacral region of vertebral column has exact synonym caudal-sacral vertebrae series

Changes for: gingiva

Deleted
- - gingiva comment Editor notes: FMA has a 3-level breakdown of jaws into: region, jaw (skeleton+gums), skeleton.
Added
- + gingiva editor note FMA has a 3-level breakdown of jaws into: region, jaw (skeleton+gums), skeleton.

Changes for: embryonic skin basal layer

Deleted
- - embryonic skin basal layer comment Editor notes: compare with ‘stratum basale of epidermis’. This class is the source for many adult structures - see WP2062. See also: ‘enveloping layer of ectoderm’
Added
- + embryonic skin basal layer editor note compare with ‘stratum basale of epidermis’. This class is the source for many adult structures - see WP2062. See also: ‘enveloping layer of ectoderm’

Changes for: hyoepiglottic ligament

Deleted
- - hyoepiglottic ligament SubClassOf connects some epiglottis
- - hyoepiglottic ligament SubClassOf connects some hyoid bone body
Added
- + hyoepiglottic ligament SubClassOf connects some epiglottis
- + hyoepiglottic ligament SubClassOf connects some hyoid bone body

Changes for: prehallux skeleton

Deleted
- - prehallux skeleton SubClassOf preaxial part of some tarsal skeleton
Added
- + prehallux skeleton SubClassOf preaxialmost part of some tarsal skeleton

Changes for: hepatogastric ligament

Deleted
- - hepatogastric ligament SubClassOf connects some liver
- - hepatogastric ligament SubClassOf connects some stomach
Added
- + hepatogastric ligament SubClassOf connects some liver
- + hepatogastric ligament SubClassOf connects some stomach

Changes for: hepatoduodenal ligament

Deleted
- - hepatoduodenal ligament SubClassOf connects some duodenum
- - hepatoduodenal ligament SubClassOf connects some liver
Added
- + hepatoduodenal ligament SubClassOf connects some duodenum
- + hepatoduodenal ligament SubClassOf connects some liver

Changes for: extraembryonic cavities

Deleted
- - extraembryonic cavities SubClassOf part of some extraembryonic structure
Added
- + extraembryonic cavities SubClassOf part of some entire extraembryonic component

Changes for: cranial ganglion

Deleted
- - cranial ganglion comment Editor note: split out MA ter,. Note the MA term is part of the CNS. This needs to be checked w.r.t relationship between ganglia and the PNS, as the PNS and CNS are spatially disjoint. also meaning of MA term is not clear (appears to be union of nerve and ganglion, but MA ‘cranial nerve’ is unconnected)
Added
- + cranial ganglion editor note split out MA ter,. Note the MA term is part of the CNS. This needs to be checked w.r.t relationship between ganglia and the PNS, as the PNS and CNS are spatially disjoint. also meaning of MA term is not clear (appears to be union of nerve and ganglion, but MA ‘cranial nerve’ is unconnected)

Changes for: secondary palate

Deleted
- - secondary palate comment Function notes: separates respiratory and oral passages. Taxon notes: present in mammals and some reptiles. A similar structure is found in crocodilians, but, in most other tetrapods, the oral and nasal cavities are not truly separate. The secondary palate is formed by bilateral medial extensions of maxillary processes. The extensions (palatine processes) meet at the midline, merging dorsally with nasal septum and rostrally with primary palate. The secondary palate (hard palate) separates nasal and oral cavities. Caudal extension of the secondary palate into the pharynx, forms a soft palate which divides the rostral pharynx into dorsal (nasopharynx) and ventral (oropharynx) chamber.
Added
- + secondary palate comment Taxon notes: present in mammals and some reptiles. A similar structure is found in crocodilians, but, in most other tetrapods, the oral and nasal cavities are not truly separate. The secondary palate is formed by bilateral medial extensions of maxillary processes. The extensions (palatine processes) meet at the midline, merging dorsally with nasal septum and rostrally with primary palate. The secondary palate (hard palate) separates nasal and oral cavities. Caudal extension of the secondary palate into the pharynx, forms a soft palate which divides the rostral pharynx into dorsal (nasopharynx) and ventral (oropharynx) chamber.
- + secondary palate function notes separates respiratory and oral passages

Changes for: geniculate ganglion

Deleted
- - geniculate ganglion comment Editor notes: resolve facial VII vs geniculate (see EHDAA2)
Added
- + geniculate ganglion editor note resolve facial VII vs geniculate (see EHDAA2)

Changes for: cerebral vein

Added
- + cerebral vein fma set term http://purl.obolibrary.org/obo/FMA_70861

Changes for: mandible

Deleted
- - mandible comment Editor notes: consider merging with dentary - for now we make it a mammal-specific subclass. Terminology notes: ‘mandible’ also refers to either the upper OR lower part of the beak in birds. AO notes: Note in ZFA ‘mandible’ is a syn for the ventral mandibular arch, which is a portion of the 1st pharyngeal arch; however the term ‘mandibular symphysis’ refers to the dentary
Added
- + mandible comment AO notes: Note in ZFA ‘mandible’ is a syn for the ventral mandibular arch, which is a portion of the 1st pharyngeal arch; however the term ‘mandibular symphysis’ refers to the dentary
- + mandible editor note consider merging with dentary - for now we make it a mammal-specific subclass. Terminology notes: ‘mandible’ also refers to either the upper OR lower part of the beak in birds

Changes for: bronchoalveolar duct junction

Deleted
- - bronchoalveolar duct junction SubClassOf connects some pulmonary alveolar duct
- - bronchoalveolar duct junction SubClassOf connects some respiratory bronchiole
Added
- + bronchoalveolar duct junction SubClassOf connects some pulmonary alveolar duct
- + bronchoalveolar duct junction SubClassOf connects some respiratory bronchiole

Changes for: vestibular nuclear complex

Deleted
- - vestibular nuclear complex comment Editor notes: In TA they are grouped in both the pons and medulla; WP+MA says the SVN is in the pons, and GO includes VNC development under pons development, but this is not supported by ABA. Todo - check with NIF.
Added
- + vestibular nuclear complex editor note In TA they are grouped in both the pons and medulla; WP+MA says the SVN is in the pons, and GO includes VNC development under pons development, but this is not supported by ABA. Todo - check with NIF.

Changes for: preopercle vertical limb-hyomandibula joint

Deleted
- - preopercle vertical limb-hyomandibula joint EquivalentTo skeletal joint and connects some hyomandibular bone and connects some preopercle vertical limb
- - preopercle vertical limb-hyomandibula joint SubClassOf connects some hyomandibular bone
- - preopercle vertical limb-hyomandibula joint SubClassOf connects some preopercle vertical limb
Added
- + preopercle vertical limb-hyomandibula joint EquivalentTo skeletal joint and connects some hyomandibular bone and connects some preopercle vertical limb
- + preopercle vertical limb-hyomandibula joint SubClassOf connects some hyomandibular bone
- + preopercle vertical limb-hyomandibula joint SubClassOf connects some preopercle vertical limb

Changes for: fenestrated capillary

Deleted
- - fenestrated capillary comment Editor notes: the ZFA class from which this was derived is not explicitly classified as a capillary - need to verify for taxon histology differences
Added
- + fenestrated capillary editor note the ZFA class from which this was derived is not explicitly classified as a capillary - need to verify for taxon histology differences

Changes for: hyomandibula-opercle joint

Deleted
- - hyomandibula-opercle joint EquivalentTo skeletal joint and connects some hyomandibular bone and connects some opercle
- - hyomandibula-opercle joint SubClassOf connects some hyomandibular bone
- - hyomandibula-opercle joint SubClassOf connects some opercle
Added
- + hyomandibula-opercle joint EquivalentTo skeletal joint and connects some hyomandibular bone and connects some opercle
- + hyomandibula-opercle joint SubClassOf connects some hyomandibular bone
- + hyomandibula-opercle joint SubClassOf connects some opercle

Changes for: supraoccipital-parietal joint

Deleted
- - supraoccipital-parietal joint EquivalentTo skeletal joint and connects some supraoccipital bone and connects some actinopterygian parietal bone
- - supraoccipital-parietal joint SubClassOf connects some actinopterygian parietal bone
- - supraoccipital-parietal joint SubClassOf connects some supraoccipital bone
Added
- + supraoccipital-parietal joint EquivalentTo skeletal joint and connects some supraoccipital bone and connects some actinopterygian parietal bone
- + supraoccipital-parietal joint SubClassOf connects some actinopterygian parietal bone
- + supraoccipital-parietal joint SubClassOf connects some supraoccipital bone

Changes for: preopercle horizontal limb-symplectic joint

Deleted
- - preopercle horizontal limb-symplectic joint EquivalentTo skeletal joint and connects some preopercle horizontal limb and connects some symplectic
- - preopercle horizontal limb-symplectic joint SubClassOf connects some preopercle horizontal limb
- - preopercle horizontal limb-symplectic joint SubClassOf connects some symplectic
Added
- + preopercle horizontal limb-symplectic joint EquivalentTo skeletal joint and connects some preopercle horizontal limb and connects some symplectic
- + preopercle horizontal limb-symplectic joint SubClassOf connects some preopercle horizontal limb
- + preopercle horizontal limb-symplectic joint SubClassOf connects some symplectic

Changes for: periamygdaloid area

Added
- + periamygdaloid area database cross reference http://www.snomedbrowser.com/Codes/Details/279214005

Changes for: bifurcation of trachea

Deleted
- - bifurcation of trachea SubClassOf connects some main bronchus
- - bifurcation of trachea SubClassOf connects some trachea
Added
- + bifurcation of trachea SubClassOf connects some main bronchus
- + bifurcation of trachea SubClassOf connects some trachea

Changes for: azygos vein

Deleted
- - azygos vein comment Editor notes: check development relationships in different species
Added
- + azygos vein editor note check development relationships in different species

Changes for: internal thoracic vein

Deleted
- - internal thoracic vein comment Editor notes: check relationship to ‘internal mammary vein’ in MA
Added
- + internal thoracic vein editor note check relationship to ‘internal mammary vein’ in MA

Changes for: esophagus muscle

Deleted
- - esophagus muscle comment Editor notes: merge muscle and muscle layer?
Added
- + esophagus muscle editor note merge muscle and muscle layer?

Changes for: collection of basal ganglia

Deleted
- - collection of basal ganglia comment Editor note: it is necessary to introduce two classes, one representing an individual basal ganglion, another representing the aggregate structure, in order to have consistent classification amongst AOs (e.g. in MA the aygdala is part of the BG, in FMA and BTO it is a subclass). Apart from achieving this consistency, the value of having two distinct classes is questionable, since the BG-plural is trivially the collection of all BGs-singular. it would be better for all AOs to decide on one single way of doing this. Do not merge until this is done.
Added
- + collection of basal ganglia editor note it is necessary to introduce two classes, one representing an individual basal ganglion, another representing the aggregate structure, in order to have consistent classification amongst AOs (e.g. in MA the aygdala is part of the BG, in FMA and BTO it is a subclass). Apart from achieving this consistency, the value of having two distinct classes is questionable, since the BG-plural is trivially the collection of all BGs-singular. it would be better for all AOs to decide on one single way of doing this. Do not merge until this is done.

Changes for: stomach non-glandular epithelium

Deleted
- - stomach non-glandular epithelium comment Editor notes: OWL definition to be added later. Taxon notes: this region may develop from the base of the esophagus (some herbivores) - in rodents, loss of the gastric glands in the mucosa leavea a nonglandular epithelial stomach in which smooth muscle contractions knead and mix digesta. This can be keratinized.
Added
- + stomach non-glandular epithelium comment Taxon notes: this region may develop from the base of the esophagus (some herbivores) - in rodents, loss of the gastric glands in the mucosa leavea a nonglandular epithelial stomach in which smooth muscle contractions knead and mix digesta. This can be keratinized.
- + stomach non-glandular epithelium editor note OWL definition to be added later

Changes for: extra-ocular muscle

Added
- + extra-ocular muscle has relational adjective extraocular

Changes for: fundic gastric gland

Deleted
- - fundic gastric gland comment Editor notes: Consider FMA:14923
Added
- + fundic gastric gland editor note Consider FMA:14923 ! Principal gland of fundus of stomach. Added part_of to mucosa to be consistent with FMA pattern (note that Kardong places this in the glandular epithelium)

Changes for: stapes cartilage element

Deleted
- - stapes cartilage element comment Editor notes: TODO - check relationship to Recihert’s. Taxon notes: The stapes is homologous to the hyomandibula. In this ontology, we use the class ‘hyomandibular cartilage’ generally to include the future stapes, the future hyomandibular bone of teleosts and the unossified cartilage in sharks.
Added
- + stapes cartilage element comment Taxon notes: The stapes is homologous to the hyomandibula. In this ontology, we use the class ‘hyomandibular cartilage’ generally to include the future stapes, the future hyomandibular bone of teleosts and the unossified cartilage in sharks.
- + stapes cartilage element editor note TODO - check relationship to Recihert’s

Changes for: mesencephalic artery

Deleted
- - mesencephalic artery comment Editor notes: review this term, check taxon scope
Added
- + mesencephalic artery editor note review this term, check taxon scope

Changes for: mucosa of dorsum of tongue

Deleted
- - mucosa of dorsum of tongue comment Editor notes: check surface terms. Development notes: develops fungiform papillae by WNT induction at 11 weeks pc in human. Filiform papillae develop later. ISBN10:1607950324
Added
- + mucosa of dorsum of tongue comment Development notes: develops fungiform papillae by WNT induction at 11 weeks pc in human. Filiform papillae develop later. ISBN10:1607950324
- + mucosa of dorsum of tongue editor note check surface terms

Changes for: artery

Deleted
- - artery comment Editor notes: Note that in FMA an artery is a tree, whereas AEO/JB defines it as a tube; FMA includes a separate class for what it calls the trunk. Classification in this ontology may currently (Jan 2012) represent a mix of both schemes, although we are gradually revising in the direction of the AEO scheme.
Added
- + artery editor note Note that in FMA an artery is a tree, whereas AEO/JB defines it as a tube; FMA includes a separate class for what it calls the trunk. Classification in this ontology may currently (Jan 2012) represent a mix of both schemes, although we are gradually revising in the direction of the AEO scheme.

Changes for: future dermis

Deleted
- - future dermis comment Editor notes: check development
Added
- + future dermis editor note check development

Changes for: optic choroid vascular plexus

Deleted
- - optic choroid vascular plexus comment Editor notes: Consider merging with capillary layer. Consider choriocapillaris complex
Added
- + optic choroid vascular plexus editor note Consider merging with capillary layer. Consider choriocapillaris complex

Changes for: tapetum lucidum of camera-type eye

Deleted
- - tapetum lucidum of camera-type eye comment Function notes: It normally functions at low light levels to provide the light-sensitive retinal cells with a second opportunity for photon-photoreceptor stimulation, thereby enhancing visual sensitivity
Added
- + tapetum lucidum of camera-type eye function notes It normally functions at low light levels to provide the light-sensitive retinal cells with a second opportunity for photon-photoreceptor stimulation, thereby enhancing visual sensitivity

Changes for: distal visceral endoderm

Deleted
- - distal visceral endoderm SubClassOf develops from some endoderm
- - distal visceral endoderm SubClassOf endoderm-derived structure
- - distal visceral endoderm SubClassOf extraembryonic structure
Added
- + distal visceral endoderm SubClassOf visceral endoderm

Changes for: dermatological-muscosal system

Added
- + dermatological-muscosal system SubClassOf existence ends during some fully formed stage

Changes for: male prepuce epithelium

Deleted
- - male prepuce epithelium comment Editor notes: NCITA term may be sex-neutral
Added
- + male prepuce epithelium editor note NCITA term may be sex-neutral

Changes for: infraspinatus tendon

Deleted
- - infraspinatus tendon SubClassOf connects some greater tubercle of humerus
- - infraspinatus tendon SubClassOf connects some infraspinatus muscle
Added
- + infraspinatus tendon SubClassOf connects some greater tubercle of humerus
- + infraspinatus tendon SubClassOf connects some infraspinatus muscle

Changes for: lip skeletal muscle

Deleted
- - lip skeletal muscle comment Muscles acting on the lips
Added
- + lip skeletal muscle editor note Muscles acting on the lips

Changes for: intercuneiform joint

Deleted
- - intercuneiform joint SubClassOf ObjectMinCardinality( connects distal tarsal bone ) and ObjectMaxCardinality( connects distal tarsal bone )
- - intercuneiform joint SubClassOf connects some distal tarsal bone
Added
- + intercuneiform joint SubClassOf ObjectMinCardinality( connects distal tarsal bone ) and ObjectMaxCardinality( connects distal tarsal bone )
- + intercuneiform joint SubClassOf connects some distal tarsal bone

Changes for: posterior nuclear complex of thalamus

Deleted
- - posterior nuclear complex of thalamus comment Editor note: ZFA grouping dubious
Added
- + posterior nuclear complex of thalamus editor note ZFA grouping dubious

Changes for: nasion

Deleted
- - nasion EquivalentTo anatomical point and connects some tetrapod frontal bone and connects some nasal skeleton
- - nasion SubClassOf connects some nasal skeleton
- - nasion SubClassOf connects some tetrapod frontal bone
Added
- + nasion EquivalentTo anatomical point and connects some tetrapod frontal bone and connects some nasal skeleton
- + nasion SubClassOf connects some nasal skeleton
- + nasion SubClassOf connects some tetrapod frontal bone

Changes for: intergluteal cleft

Deleted
- - intergluteal cleft SubClassOf ObjectMinCardinality( connects buttock ) and ObjectMaxCardinality( connects buttock )
- - intergluteal cleft SubClassOf connects some buttock
Added
- + intergluteal cleft SubClassOf ObjectMinCardinality( connects buttock ) and ObjectMaxCardinality( connects buttock )
- + intergluteal cleft SubClassOf connects some buttock

Changes for: basal part of pons

Added
- + basal part of pons database cross reference http://www.snomedbrowser.com/Codes/Details/361541001
- + basal part of pons has exact synonym ventral pons

Changes for: cranial placode

Deleted
- - cranial placode comment Editor note: to avoid confusion, we include neurogenic placode as a subclass. Do not merge. Terminological notes: The term placode or placodes also applies to developing organs such as teeth, mammary glands, hair follicles, feathers and scales. We include a separate parent class for this. Taxon notes: Comparisons of developmental gene expression suggest that the anterior ectoderm in amphioxus may be homologous to the vertebrate olfactory placode, the only vertebrate placode with primary, not secondary, neurons[PMID:11523831].
Added
- + cranial placode comment .
- + cranial placode editor note to avoid confusion, we include neurogenic placode as a subclass. Do not merge. Terminological notes: The term placode or placodes also applies to developing organs such as teeth, mammary glands, hair follicles, feathers and scales. We include a separate parent class for this. Taxon notes: Comparisons of developmental gene expression suggest that the anterior ectoderm in amphioxus may be homologous to the vertebrate olfactory placode, the only vertebrate placode with primary, not secondary, neurons[PMID:11523831]

Changes for: upper secondary premolar tooth

Deleted
- - upper secondary premolar tooth SubClassOf premolar tooth
- - upper secondary premolar tooth SubClassOf tooth of lower jaw
Added
- + upper secondary premolar tooth SubClassOf lower premolar tooth

Changes for: lower secondary premolar tooth

Deleted
- - lower secondary premolar tooth SubClassOf premolar tooth
- - lower secondary premolar tooth SubClassOf tooth of lower jaw
Added
- + lower secondary premolar tooth SubClassOf lower premolar tooth

Changes for: arthropod sensillum

Deleted
- - arthropod sensillum comment Editor notes: this term should be ceded to the arthropod anatomy ontology
Added
- + arthropod sensillum editor note this term should be ceded to the arthropod anatomy ontology

Changes for: post-anal tail bud

Deleted
- - post-anal tail bud comment Editor notes: See notes from UBERONREF:0000002
Added
- + post-anal tail bud editor note See notes from UBERONREF:0000002

Changes for: tunica intima

Deleted
- - tunica intima comment Editor note: the FMA class represents a more generic layer which is the superclass of the layer found in both blood vessels and lymph vessels (and also endocardium) - we should probably follow this structure
Added
- + tunica intima editor note the FMA class represents a more generic layer which is the superclass of the layer found in both blood vessels and lymph vessels (and also endocardium) - we should probably follow this structure

Changes for: otolith organ

Deleted
- - otolith organ comment Editor notes: Representation of utricle, sacule and otoliths in correspondence to other ontologies may require review. In EHDAA2, saccule and utricle are epithelia
Added
- + otolith organ editor note Representation of utricle, sacule and otoliths in correspondence to other ontologies may require review. In EHDAA2, saccule and utricle are epithelia

Changes for: epiphyseal plate

Deleted
- - epiphyseal plate comment editor note: consider splitting this class into the epiphyseal plates of long bones and vertebrae
Added
- + epiphyseal plate editor note consider splitting this class into the epiphyseal plates of long bones and vertebrae

Changes for: anterior fontanel

Deleted
- - anterior fontanel EquivalentTo fontanelle and connects some coronal suture and connects some frontal suture and connects some sagittal suture
- - anterior fontanel SubClassOf connects some coronal suture
- - anterior fontanel SubClassOf connects some frontal suture
- - anterior fontanel SubClassOf connects some sagittal suture
Added
- + anterior fontanel EquivalentTo fontanelle and connects some coronal suture and connects some frontal suture and connects some sagittal suture
- + anterior fontanel SubClassOf connects some coronal suture
- + anterior fontanel SubClassOf connects some frontal suture
- + anterior fontanel SubClassOf connects some sagittal suture

Changes for: skeletal system

Added
- + skeletal system SubClassOf existence ends during some fully formed stage

Changes for: tongue taste bud

Deleted
- - tongue taste bud comment Editor notes: sibling classes have yet to be added
Added
- + tongue taste bud editor note sibling classes have yet to be added

Changes for: metaphysis

Deleted
- - metaphysis comment adjacent to or containing epiphyseal plate? Note in FMA the metaphysis is part of the diaphysis, but not in MA. In the diagram in WP, it appears to be adjacent, not part_of.
Added
- + metaphysis comment adjacent to or containing epiphyseal plate? Note in FMA the metaphysis is part of the diaphysis, but not in MA.

Changes for: elbow joint

Deleted
- - elbow joint EquivalentTo skeletal joint and connects some humerus and connects some forelimb zeugopod skeleton
- - elbow joint SubClassOf connects some forelimb zeugopod skeleton
- - elbow joint SubClassOf connects some humerus
Added
- + elbow joint EquivalentTo skeletal joint and connects some humerus and connects some forelimb zeugopod skeleton
- + elbow joint SubClassOf connects some forelimb zeugopod skeleton
- + elbow joint SubClassOf connects some humerus

Changes for: wrist joint

Deleted
- - wrist joint EquivalentTo skeletal joint and connects some carpal skeleton and connects some forelimb zeugopod skeleton
- - wrist joint SubClassOf connects some carpal skeleton
- - wrist joint SubClassOf connects some forelimb zeugopod skeleton
Added
- + wrist joint EquivalentTo skeletal joint and connects some carpal skeleton and connects some forelimb zeugopod skeleton
- + wrist joint SubClassOf connects some carpal skeleton
- + wrist joint SubClassOf connects some forelimb zeugopod skeleton

Changes for: placental cotyledon

Deleted
- - mammalian cotyledon definition Round structure consisting of chorionic villi[PMID]. A separations of the decidua basalis of the placenta, separated by placental septa. Each cotyledon consists of a main stem of a chorionic villus as well as its branches and subbranches. The cotyledons receive fetal blood from chorionic vessels, which branch off cotyledon vessels into the cotyledons, which, in turn, branch into capillaries. The cotyledons are surrounded by maternal blood, which can exchange oxygen and nutrients with the fetal blood in the capillaries[WP]. { database cross reference=http://en.wikipedia.org/wiki/Placental_cotyledon , database cross reference=http://www.ncbi.nlm.nih.gov/pubmed/19829370 }
- - mammalian cotyledon label mammalian cotyledon
Added
- + placental cotyledon SubClassOf has part some chorionic villus
- + placental cotyledon database cross reference http://www.snomedbrowser.com/Codes/Details/256491001
- + placental cotyledon definition Round structure consisting of chorionic villi[PMID]. A separation of the decidua basalis of the placenta, separated by placental septa. Each cotyledon consists of a main stem of a chorionic villus as well as its branches and subbranches. The cotyledons receive fetal blood from chorionic vessels, which branch off cotyledon vessels into the cotyledons, which, in turn, branch into capillaries. The cotyledons are surrounded by maternal blood, which can exchange oxygen and nutrients with the fetal blood in the capillaries[WP]. { database cross reference=http://en.wikipedia.org/wiki/Placental_cotyledon , database cross reference=http://www.ncbi.nlm.nih.gov/pubmed/19829370 }
- + placental cotyledon has related synonym discoid placenta
- + placental cotyledon label placental cotyledon

Changes for: knee joint

Deleted
- - knee joint EquivalentTo skeletal joint and connects some tibia and connects some femur and connects some patella
- - knee joint SubClassOf connects some femur
- - knee joint SubClassOf connects some patella
- - knee joint SubClassOf connects some tibia
Added
- + knee joint EquivalentTo skeletal joint and connects some tibia and connects some femur and connects some patella
- + knee joint SubClassOf connects some femur
- + knee joint SubClassOf connects some patella
- + knee joint SubClassOf connects some tibia

Changes for: temporomandibular joint

Deleted
- - temporomandibular joint EquivalentTo skeletal joint and connects some squamous part of temporal bone and connects some dentary
- - temporomandibular joint SubClassOf connects some dentary
- - temporomandibular joint SubClassOf connects some squamous part of temporal bone
Added
- + temporomandibular joint EquivalentTo skeletal joint and connects some squamous part of temporal bone and connects some dentary
- + temporomandibular joint SubClassOf connects some dentary
- + temporomandibular joint SubClassOf connects some squamous part of temporal bone

Changes for: ankle joint

Deleted
- - ankle joint EquivalentTo skeletal joint and connects some skeleton of pes and connects some hindlimb zeugopod skeleton
- - ankle joint SubClassOf connects some hindlimb zeugopod skeleton
- - ankle joint SubClassOf connects some skeleton of pes
Added
- + ankle joint EquivalentTo skeletal joint and connects some skeleton of pes and connects some hindlimb zeugopod skeleton
- + ankle joint SubClassOf connects some hindlimb zeugopod skeleton
- + ankle joint SubClassOf connects some skeleton of pes

Changes for: placental labyrinth villous

Added
- + placental labyrinth villous SubClassOf extraembryonic structure

Changes for: hip joint

Deleted
- - hip joint EquivalentTo skeletal joint and connects some femur and connects some acetabular part of hip bone
- - hip joint SubClassOf connects some acetabular part of hip bone
- - hip joint SubClassOf connects some femur
Added
- + hip joint EquivalentTo skeletal joint and connects some femur and connects some acetabular part of hip bone
- + hip joint SubClassOf connects some acetabular part of hip bone
- + hip joint SubClassOf connects some femur

Changes for: calcaneal tendon

Deleted
- - calcaneal tendon EquivalentTo skeletal ligament and connects some calcaneus
- - calcaneal tendon SubClassOf connects some calcaneus
- - calcaneal tendon SubClassOf connects some muscle of leg
Added
- + calcaneal tendon EquivalentTo skeletal ligament and connects some calcaneus
- + calcaneal tendon SubClassOf connects some calcaneus
- + calcaneal tendon SubClassOf connects some muscle of leg

Changes for: glenohumeral joint

Deleted
- - glenohumeral joint EquivalentTo skeletal joint and connects some humerus and connects some scapula
- - glenohumeral joint SubClassOf connects some humerus
- - glenohumeral joint SubClassOf connects some scapula
- - glenohumeral joint SubClassOf develops from some shoulder joint primordium
- - glenohumeral joint SubClassOf joint of girdle
- - glenohumeral joint has exact synonym joint of shoulder { database cross reference=OBOL:automatic }
- - glenohumeral joint has exact synonym shoulder joint { database cross reference=MA:0000459 }
- - glenohumeral joint has related synonym articulatio humeri { database cross reference=http://en.wikipedia.org/wiki/Glenohumeral_joint , has synonym type=latin term }
Added
- + glenohumeral joint EquivalentTo skeletal joint and connects some humerus and connects some scapula
- + glenohumeral joint SubClassOf connects some humerus
- + glenohumeral joint SubClassOf connects some scapula
- + glenohumeral joint SubClassOf shoulder joint
- + glenohumeral joint SubClassOf synovial joint of pectoral girdle
- + glenohumeral joint SubClassOf synovial limb joint
- + glenohumeral joint has broad synonym joint of shoulder { database cross reference=OBOL:automatic }
- + glenohumeral joint has broad synonym shoulder joint { database cross reference=MA:0000459 }

Changes for: sternoclavicular joint

Deleted
- - sternoclavicular joint EquivalentTo skeletal joint and connects some sternum and connects some clavicle
- - sternoclavicular joint SubClassOf connects some clavicle
- - sternoclavicular joint SubClassOf connects some sternum
Added
- + sternoclavicular joint EquivalentTo skeletal joint and connects some sternum and connects some clavicle
- + sternoclavicular joint SubClassOf connects some clavicle
- + sternoclavicular joint SubClassOf connects some sternum

Changes for: intervertebral joint

Deleted
- - intervertebral joint EquivalentTo skeletal joint and ObjectMinCardinality( connects bony vertebral centrum ) and ObjectMaxCardinality( connects bony vertebral centrum )
- - intervertebral joint SubClassOf connects some bony vertebral centrum
Added
- + intervertebral joint EquivalentTo skeletal joint and ObjectMinCardinality( connects bony vertebral centrum ) and ObjectMaxCardinality( connects bony vertebral centrum )
- + intervertebral joint SubClassOf connects some bony vertebral centrum

Changes for: proximal interphalangeal joint

Deleted
- - proximal interphalangeal joint EquivalentTo interphalangeal joint and connects some proximal phalanx
- - proximal interphalangeal joint SubClassOf connects some middle phalanx
- - proximal interphalangeal joint SubClassOf connects some proximal phalanx
Added
- + proximal interphalangeal joint EquivalentTo interphalangeal joint and connects some proximal phalanx
- + proximal interphalangeal joint SubClassOf connects some middle phalanx
- + proximal interphalangeal joint SubClassOf connects some proximal phalanx

Changes for: distal interphalangeal joint

Deleted
- - distal interphalangeal joint EquivalentTo interphalangeal joint and connects some distal phalanx
- - distal interphalangeal joint SubClassOf connects some distal phalanx
Added
- + distal interphalangeal joint EquivalentTo interphalangeal joint and connects some distal phalanx
- + distal interphalangeal joint SubClassOf connects some distal phalanx

Changes for: trachea cartilage

Deleted
- - trachea cartilage comment Editor notes: check whether to classify as part of splanchoncranium. Taxon notes: in avians the rings are complete.
Added
- + trachea cartilage comment Taxon notes: in avians the rings are complete.
- + trachea cartilage editor note check whether to classify as part of splanchoncranium

Changes for: cardiac mesenchyme

Deleted
- - cardiac mesenchyme comment Editor note: decide whether to merge with cardiac mesoderm. In EHDAA2 this lasts CS12->unbounded, includes mesenchyme of individual components as parts
Added
- + cardiac mesenchyme editor note decide whether to merge with cardiac mesoderm. In EHDAA2 this lasts CS12->unbounded, includes mesenchyme of individual components as parts

Changes for: visceral yolk sac cavity

Deleted
- - visceral yolk sac cavity SubClassOf mixed endoderm/mesoderm-derived structure
Added
- + visceral yolk sac cavity SubClassOf yolk sac endoderm

Changes for: radio-ulnar joint

Deleted
- - radio-ulnar joint EquivalentTo skeletal joint and connects some radius bone and connects some ulna
- - radio-ulnar joint SubClassOf connects some radius bone
- - radio-ulnar joint SubClassOf connects some ulna
Added
- + radio-ulnar joint EquivalentTo skeletal joint and connects some radius bone and connects some ulna
- + radio-ulnar joint SubClassOf connects some radius bone
- + radio-ulnar joint SubClassOf connects some ulna

Changes for: skin mucous gland

Deleted
- - skin mucous gland SubClassOf skin gland
- - skin mucous gland definition A mucous gland that is part of a skin of body. { database cross reference=OBOL:automatic }
Added
- + skin mucous gland SubClassOf epidermis gland
- + skin mucous gland SubClassOf part of some skin epidermis
- + skin mucous gland definition A mucous gland that is part of the skin. { database cross reference=UBERON:cjm }

Changes for: upper jaw molar

Deleted
- - upper jaw molar has narrow synonym upper primary molar tooth { database cross reference=FMA:84210 }

Changes for: mouth floor

Added
- + mouth floor has exact synonym floor of oval cavity

Changes for: left common carotid artery plus branches

Deleted
- - left common carotid artery plus branches comment Editor notes: placement of the MA class here is not strictly correct, as the MA class does not include the branches
Added
- + left common carotid artery plus branches editor note placement of the MA class here is not strictly correct, as the MA class does not include the branches

Changes for: common carotid artery plus branches

Deleted
- - common carotid artery plus branches comment Editor notes: we follow the FMA and treat the artery as a tree-structure - here we include the internal and external as parts. For the part that excludes the branches, see ‘trunk of common carotid artery’. Development notes: in birds and reptiles, develops from arch III and parts of ventral and dorsal aortae
Added
- + common carotid artery plus branches comment Development notes: in birds and reptiles, develops from arch III and parts of ventral and dorsal aortae
- + common carotid artery plus branches editor note we follow the FMA and treat the artery as a tree-structure - here we include the internal and external as parts. For the part that excludes the branches, see ‘trunk of common carotid artery’

Changes for: right common carotid artery plus branches

Deleted
- - right common carotid artery plus branches comment Editor notes: placement of the MA class here is not strictly correct, as the MA class does not include the branches
Added
- + right common carotid artery plus branches editor note placement of the MA class here is not strictly correct, as the MA class does not include the branches

Changes for: patellar ligament

Deleted
- - patellar ligament SubClassOf connects some patella
- - patellar ligament SubClassOf connects some tibia
Added
- + patellar ligament SubClassOf connects some patella
- + patellar ligament SubClassOf connects some tibia

Changes for: articular system

Added
- + articular system SubClassOf existence ends during some fully formed stage

Changes for: esophageal-pneumatic duct sphincter

Deleted
- - esophageal-pneumatic duct sphincter EquivalentTo sphincter muscle and part of some esophagus and connects some esophagus and connects some pneumatic duct
- - esophageal-pneumatic duct sphincter SubClassOf connects some esophagus
- - esophageal-pneumatic duct sphincter SubClassOf connects some pneumatic duct
Added
- + esophageal-pneumatic duct sphincter EquivalentTo sphincter muscle and part of some esophagus and connects some esophagus and connects some pneumatic duct
- + esophageal-pneumatic duct sphincter SubClassOf connects some esophagus
- + esophageal-pneumatic duct sphincter SubClassOf connects some pneumatic duct

Changes for: bone of lower jaw

Deleted
- - bone of lower jaw comment Editor notes: Do not manually classify under here - bones are automatically classified
Added
- + bone of lower jaw editor note Do not manually classify under here - bones are automatically classified

Changes for: sella turcica

Deleted
- - sella turcica comment Editor notes: for consistency with FMA we have a separate class for the cavity of the sella turcica
Added
- + sella turcica editor note for consistency with FMA we have a separate class for the cavity of the sella turcica

Changes for: segmental subdivision of nervous system

Deleted
- - segmental subdivision of nervous system comment Editor note: revisit this after CARO is revised and/or we have defined metameric segment; note that with the additional of an A/P axis constraint this corresponds to what Richter at al call a neuromere (PMID:21062451)
Added
- + segmental subdivision of nervous system editor note revisit this after CARO is revised and/or we have defined metameric segment; note that with the additional of an A/P axis constraint this corresponds to what Richter at al call a neuromere (PMID:21062451)

Changes for: instar larval stage

Added
- + instar larval stage present in taxon http://purl.obolibrary.org/obo/NCBITaxon_7227

Changes for: palatal muscle

Deleted
- - palatal muscle comment Editor notes: consider extra class for fauces. AO notes: see also FMA:71438
Added
- + palatal muscle comment AO notes: see also FMA:71438
- + palatal muscle editor note consider extra class for fauces

Changes for: coracoid bone

Deleted
- - coracoid bone comment Editor notes: check developmental relationships. Taxon notes: In Theria, coracoid bones non-existent or fused with the shoulder blades to form coracoid processes[WP]. Procoracoid+coracoid are homologuous with coracoid of teleostomi. The coracoid is a triangular shaped-bone that usually has an anteriorly directed long process that may joins its counterpart in some fish groups. It may be perforated by the coracoid foramen or it may be notched dorsally and forms the scapulo-coracoid foramen together with a similar notch of the ventral margin of the scapula[VSAO] Terminology notes: see discussion in Kardong - suggests using procoracoid (anterior coracoid) for the element in birds, reptiles, amphibians and fish, and reserving coracoid for the new synapsid/therian structure.
Added
- + coracoid bone comment Terminology notes: see discussion in Kardong - suggests using procoracoid (anterior coracoid) for the element in birds, reptiles, amphibians and fish, and reserving coracoid for the new synapsid/therian structure.
- + coracoid bone editor note check developmental relationships. Taxon notes: In Theria, coracoid bones non-existent or fused with the shoulder blades to form coracoid processes[WP]. Procoracoid+coracoid are homologuous with coracoid of teleostomi. The coracoid is a triangular shaped-bone that usually has an anteriorly directed long process that may joins its counterpart in some fish groups. It may be perforated by the coracoid foramen or it may be notched dorsally and forms the scapulo-coracoid foramen together with a similar notch of the ventral margin of the scapula[VSAO]

Changes for: pubic symphysis

Deleted
- - pubic symphysis SubClassOf connects some skeleton of left pelvic girdle
- - pubic symphysis SubClassOf connects some skeleton of right pelvic girdle
Added
- + pubic symphysis SubClassOf connects some skeleton of left pelvic girdle
- + pubic symphysis SubClassOf connects some skeleton of right pelvic girdle

Changes for: articular/anguloarticular

Deleted
- - articular/anguloarticular comment Editor notes: We create different classes for articular and malleus, in contrast to VHOG. Taxon notes (from VHOG): “According to this theory [Reichert-Gaupp theory], the mammalian stapes is derived from the reptilian columella, the incus from the quadrate and the malleus from the articular […]” Gerrie J, The phylogeny of the mammalian tympanic cavity and auditory ossicles. The Journal of Laryngology and Otology (1948) 62:339-357. Note that TAO has a distinct class for articular - in fact we need (at least) 3 classes here - articular, anguloarticular and malleus, arranged into a single VHOG group // TODO - resolve part_of relationships
Added
- + articular/anguloarticular comment TODO - resolve part_of relationships. AO Notes: TAO has a distinct class for articular - in fact we need (at least) 3 classes here - articular, anguloarticular and malleus, arranged into a single VHOG group

Changes for: subtalar joint

Deleted
- - subtalar joint EquivalentTo synovial joint and connects some calcaneus and connects some talus
- - subtalar joint SubClassOf connects some calcaneus
- - subtalar joint SubClassOf connects some talus
Added
- + subtalar joint EquivalentTo synovial joint and connects some calcaneus and connects some talus
- + subtalar joint SubClassOf connects some calcaneus
- + subtalar joint SubClassOf connects some talus

Changes for: metatarsophalangeal joint

Deleted
- - metatarsophalangeal joint EquivalentTo skeletal joint and connects some metatarsal bone and connects some distal phalanx of pes
- - metatarsophalangeal joint SubClassOf connects some distal phalanx of pes
- - metatarsophalangeal joint SubClassOf connects some metatarsal bone
- - metatarsophalangeal joint comment Editor notes: we follow FMA in making these joints part of digits
Added
- + metatarsophalangeal joint EquivalentTo skeletal joint and connects some metatarsal bone and connects some distal phalanx of pes
- + metatarsophalangeal joint SubClassOf connects some distal phalanx of pes
- + metatarsophalangeal joint SubClassOf connects some metatarsal bone
- + metatarsophalangeal joint editor note we follow FMA in making these joints part of digits
- + metatarsophalangeal joint has alternative id http://purl.bioontology.org/ontology/provisional/1ddd2e2d-2ace-4c87-8ec6-d3b5730b3e7c
- + metatarsophalangeal joint has alternative id http://purl.bioontology.org/ontology/provisional/8378426c-67ca-4bab-a9cf-531093b9b95e
- + metatarsophalangeal joint has exact synonym metatarsal-phalangeal joint

Changes for: metacarpophalangeal joint

Deleted
- - metacarpophalangeal joint EquivalentTo skeletal joint and connects some proximal phalanx of manus and connects some metacarpal bone
- - metacarpophalangeal joint SubClassOf connects some metacarpal bone
- - metacarpophalangeal joint SubClassOf connects some proximal phalanx of manus
- - metacarpophalangeal joint comment Editor notes: we follow FMA in making these joints part of digits. We include carpometacarpophalangeal joint as a synonym - these joints connect to the carpometacarpus - this is not necessarily inconsistent with the relationship for this class to metacarpal bone, as the carpometacarpus could be considered to have a metacarpal as part
Added
- + metacarpophalangeal joint EquivalentTo skeletal joint and connects some proximal phalanx of manus and connects some metacarpal bone
- + metacarpophalangeal joint SubClassOf connects some metacarpal bone
- + metacarpophalangeal joint SubClassOf connects some proximal phalanx of manus
- + metacarpophalangeal joint editor note we follow FMA in making these joints part of digits. We include carpometacarpophalangeal joint as a synonym - these joints connect to the carpometacarpus - this is not necessarily inconsistent with the relationship for this class to metacarpal bone, as the carpometacarpus could be considered to have a metacarpal as part

Changes for: atlanto-axial joint

Deleted
- - atlanto-axial joint SubClassOf connects some vertebral bone 1
- - atlanto-axial joint SubClassOf connects some vertebral bone 2
Added
- + atlanto-axial joint SubClassOf connects some vertebral bone 1
- + atlanto-axial joint SubClassOf connects some vertebral bone 2

Changes for: acromioclavicular joint

Deleted
- - acromioclavicular joint EquivalentTo skeletal joint and connects some clavicle and connects some scapula
- - acromioclavicular joint SubClassOf connects some clavicle
- - acromioclavicular joint SubClassOf connects some scapula
Added
- + acromioclavicular joint EquivalentTo skeletal joint and connects some clavicle and connects some scapula
- + acromioclavicular joint SubClassOf connects some clavicle
- + acromioclavicular joint SubClassOf connects some scapula
- + acromioclavicular joint SubClassOf shoulder joint

Changes for: conceptus

Deleted
- - conceptus SubClassOf has part some extraembryonic structure
- - conceptus comment Editor notes: EHDAA2 places this as a subtype of organism. This leads to the inference that a conceptus is an embryo (if an embryo is defined as an organism at embryo stage), which eliminates the embryonic + extra-embryonic = conceptus
Added
- + conceptus SubClassOf has part some entire extraembryonic component
- + conceptus editor note EHDAA2 places this as a subtype of organism. This leads to the inference that a conceptus is an embryo (if an embryo is defined as an organism at embryo stage), which eliminates the embryonic + extra-embryonic = conceptus

Changes for: amphibian larval stage

Added
- + amphibian larval stage present in taxon http://purl.obolibrary.org/obo/NCBITaxon_8355

Changes for: frontal lobe

Deleted
- - frontal lobe comment Editor note: Many species don’t have lobes but they do have frontal cortex. Lobe isn’t a really well defined term though [MM]
Added
- + frontal lobe editor note Many species don’t have lobes but they do have frontal cortex. Lobe isn’t a really well defined term though [MM]

Changes for: pseudodentary tooth

Deleted
- - pseudodentary tooth EquivalentTo calcareous tooth and attaches to some pseudodentary { source=cjm }
- - pseudodentary tooth SubClassOf attaches to some pseudodentary
Added
- + pseudodentary tooth EquivalentTo calcareous tooth and attaches to some pseudodentary { source=cjm }
- + pseudodentary tooth SubClassOf attaches to some pseudodentary

Changes for: Mullerian tubercle

Deleted
- - Mullerian tubercle SubClassOf connects some Mullerian duct
Added
- + Mullerian tubercle SubClassOf connects some Mullerian duct

Changes for: umbilical ring

Added
- + umbilical ring SubClassOf extraembryonic structure

Changes for: sacro-iliac joint

Deleted
- - sacro-iliac joint EquivalentTo skeletal joint and connects some ilium and connects some sacrum
- - sacro-iliac joint SubClassOf connects some ilium
- - sacro-iliac joint SubClassOf connects some sacrum
Added
- + sacro-iliac joint EquivalentTo skeletal joint and connects some ilium and connects some sacrum
- + sacro-iliac joint SubClassOf connects some ilium
- + sacro-iliac joint SubClassOf connects some sacrum

Changes for: umbilical artery

Deleted
- - umbilical artery comment Editor notes: todo - compare with EHDAA2. Check embryonic vs extraembryonic, developmental relationships
Added
- + umbilical artery editor note todo - compare with EHDAA2. Check embryonic vs extraembryonic, developmental relationships

Changes for: nematode larva

Added
- + nematode larva present in taxon http://purl.obolibrary.org/obo/NCBITaxon_6239

Changes for: zona limitans intrathalamica

Deleted
- - zona limitans intrathalamica comment Editor note: Modeling this as a line may not be correct - see http://code.google.com/p/caro2/issues/detail?id=17
Added
- + zona limitans intrathalamica editor note Modeling this as a line may not be correct - see http://code.google.com/p/caro2/issues/detail?id=17

Changes for: zone of stomach

Deleted
- - zone of stomach comment Editor notes: We follow Kardong in defining stomach regions by gland, but we also include ‘body of stomach’. In future we may want to have different partitions of the stomach
Added
- + zone of stomach editor note We follow Kardong in defining stomach regions by gland, but we also include ‘body of stomach’. In future we may want to have different partitions of the stomach

Changes for: femorotibial joint

Deleted
- - femorotibial joint SubClassOf connects some femur
- - femorotibial joint SubClassOf connects some tibia
- - femorotibial joint comment Editor notes: proposed OWL definition: skeletal join that connects ONLY tibia and femur
Added
- + femorotibial joint SubClassOf connects some femur
- + femorotibial joint SubClassOf connects some tibia
- + femorotibial joint editor note proposed OWL definition: skeletal join that connects ONLY tibia and femur

Changes for: corneal blood vessel

Deleted
- - corneal blood vessel comment Editor notes: follow up on tracker item
Added
- + corneal blood vessel editor note follow up on tracker item

Changes for: central sulcus

Deleted
- - central sulcus EquivalentTo sulcus of brain and connects some frontal cortex and connects some parietal lobe
- - central sulcus SubClassOf connects some frontal cortex
- - central sulcus SubClassOf connects some parietal lobe
Added
- + central sulcus EquivalentTo sulcus of brain and connects some frontal cortex and connects some parietal lobe
- + central sulcus SubClassOf connects some frontal cortex
- + central sulcus SubClassOf connects some parietal lobe

Changes for: Purkinje cell layer of cerebellar cortex

Added
- + Purkinje cell layer of cerebellar cortex EquivalentTo cerebellar layer and immediately deep to some molecular layer of cerebellar cortex and immediately superficial to some granular layer of cerebellar cortex
- + Purkinje cell layer of cerebellar cortex SubClassOf immediately deep to some molecular layer of cerebellar cortex

Changes for: nephron

Deleted
- - nephron comment Editor note: kidney terms require review for cross-vertebrate compatibility and developmental relationships. Taxon notes: In the avian kidney, three types of nephron are identified: mammalian-type nephrons with long and short loops of Henle, and reptilian type nephrons (Gambaryan, 1992)[GO Kidney]
Added
- + nephron editor note kidney terms require review for cross-vertebrate compatibility and developmental relationships. Taxon notes: In the avian kidney, three types of nephron are identified: mammalian-type nephrons with long and short loops of Henle, and reptilian type nephrons (Gambaryan, 1992)[GO Kidney]

Changes for: renal column

Deleted
- - renal column comment Editor notes: Check part_of location against textual definition
Added
- + renal column editor note Check part_of location against textual definition

Changes for: intralobular bile duct

Deleted
- - intralobular bile duct comment Editor notes: Note that this is part of the intrahepatic bile duct in MA, as this class is more alike the tree in FMA. Note also that SCT has canal of Hering and Entire IBduct as the only sibling terms under ‘Structure of intralobular bile duct’ (i.e. the CoH is the only part of the entire IBduct)
Added
- + intralobular bile duct editor note Note that this is part of the intrahepatic bile duct in MA, as this class is more alike the tree in FMA. Note also that SCT has canal of Hering and Entire IBduct as the only sibling terms under ‘Structure of intralobular bile duct’ (i.e. the CoH is the only part of the entire IBduct)

Changes for: actinopterygian frontal-parietal joint

Deleted
- - actinopterygian frontal-parietal joint EquivalentTo cranial suture and connects some actinopterygian parietal bone and connects some actinopterygian frontal bone
- - actinopterygian frontal-parietal joint SubClassOf connects some actinopterygian frontal bone
- - actinopterygian frontal-parietal joint SubClassOf connects some actinopterygian parietal bone
Added
- + actinopterygian frontal-parietal joint EquivalentTo cranial suture and connects some actinopterygian parietal bone and connects some actinopterygian frontal bone
- + actinopterygian frontal-parietal joint SubClassOf connects some actinopterygian frontal bone
- + actinopterygian frontal-parietal joint SubClassOf connects some actinopterygian parietal bone

Changes for: vestibular ligament

Deleted
- - vestibular ligament EquivalentTo ligament of larynx and connects some thyroid cartilage and connects some cuneiform cartilage
- - vestibular ligament SubClassOf connects some cuneiform cartilage
- - vestibular ligament SubClassOf connects some thyroid cartilage
Added
- + vestibular ligament EquivalentTo ligament of larynx and connects some thyroid cartilage and connects some cuneiform cartilage
- + vestibular ligament SubClassOf connects some cuneiform cartilage
- + vestibular ligament SubClassOf connects some thyroid cartilage

Changes for: thyroepiglottic ligament

Deleted
- - thyroepiglottic ligament EquivalentTo ligament of larynx and connects some thyroid cartilage and connects some epiglottic cartilage
- - thyroepiglottic ligament SubClassOf connects some epiglottic cartilage
- - thyroepiglottic ligament SubClassOf connects some thyroid cartilage
Added
- + thyroepiglottic ligament EquivalentTo ligament of larynx and connects some thyroid cartilage and connects some epiglottic cartilage
- + thyroepiglottic ligament SubClassOf connects some epiglottic cartilage
- + thyroepiglottic ligament SubClassOf connects some thyroid cartilage

Changes for: cricopharyngeal ligament

Deleted
- - cricopharyngeal ligament EquivalentTo ligament of larynx and connects some chordate pharynx and connects some cricoid cartilage
- - cricopharyngeal ligament SubClassOf connects some chordate pharynx
- - cricopharyngeal ligament SubClassOf connects some cricoid cartilage
Added
- + cricopharyngeal ligament EquivalentTo ligament of larynx and connects some chordate pharynx and connects some cricoid cartilage
- + cricopharyngeal ligament SubClassOf connects some chordate pharynx
- + cricopharyngeal ligament SubClassOf connects some cricoid cartilage

Changes for: phonic lip

Deleted
- - phonic lip comment Function notes: When the lips snap together during click production, vibrations in the dorsal bursae are likely produced ISBM10:0120885522. Large and cornified in sperm whales. Editor notes: requires review w.r.t location in physeter vs other odontocetes
Added
- + phonic lip comment Editor notes: requires review w.r.t location in physeter vs other odontocetes
- + phonic lip function notes When the lips snap together during click production, vibrations in the dorsal bursae are likely produced ISBM10:0120885522. Large and cornified in sperm whales

Changes for: cricotracheal ligament

Deleted
- - cricotracheal ligament EquivalentTo ligament of larynx and connects some cricoid cartilage and connects some trachea cartilage
- - cricotracheal ligament SubClassOf connects some cricoid cartilage
- - cricotracheal ligament SubClassOf connects some trachea cartilage
Added
- + cricotracheal ligament EquivalentTo ligament of larynx and connects some cricoid cartilage and connects some trachea cartilage
- + cricotracheal ligament SubClassOf connects some cricoid cartilage
- + cricotracheal ligament SubClassOf connects some trachea cartilage

Changes for: cricothyroid ligament

Deleted
- - cricothyroid ligament EquivalentTo ligament of larynx and connects some thyroid cartilage and connects some cricoid cartilage
- - cricothyroid ligament SubClassOf connects some cricoid cartilage
- - cricothyroid ligament SubClassOf connects some thyroid cartilage
Added
- + cricothyroid ligament EquivalentTo ligament of larynx and connects some thyroid cartilage and connects some cricoid cartilage
- + cricothyroid ligament SubClassOf connects some cricoid cartilage
- + cricothyroid ligament SubClassOf connects some thyroid cartilage

Changes for: cricoarytenoid ligament

Deleted
- - cricoarytenoid ligament EquivalentTo ligament of larynx and connects some arytenoid cartilage and connects some cricoid cartilage
- - cricoarytenoid ligament SubClassOf connects some arytenoid cartilage
- - cricoarytenoid ligament SubClassOf connects some cricoid cartilage
Added
- + cricoarytenoid ligament EquivalentTo ligament of larynx and connects some arytenoid cartilage and connects some cricoid cartilage
- + cricoarytenoid ligament SubClassOf connects some arytenoid cartilage
- + cricoarytenoid ligament SubClassOf connects some cricoid cartilage

Changes for: closed circulatory system

Deleted
- - closed circulatory system comment Editor notes: consider merging with cardiovascular system? Taxon notes: The circulatory systems of all vertebrates, as well as of annelids (for example, earthworms) and cephalopods (squid and octopus) are closed, just as in humans. Still, the systems of fish, amphibians, reptiles, and birds show various stages of the evolution of the circulatory system
Added
- + closed circulatory system editor note consider merging with cardiovascular system? Taxon notes: The circulatory systems of all vertebrates, as well as of annelids (for example, earthworms) and cephalopods (squid and octopus) are closed, just as in humans. Still, the systems of fish, amphibians, reptiles, and birds show various stages of the evolution of the circulatory system

Changes for: maxillopalatine tooth

Deleted
- - maxillopalatine tooth EquivalentTo calcareous tooth and attaches to some maxillopalatine { source=cjm }
- - maxillopalatine tooth SubClassOf attaches to some maxillopalatine
Added
- + maxillopalatine tooth EquivalentTo calcareous tooth and attaches to some maxillopalatine { source=cjm }
- + maxillopalatine tooth SubClassOf attaches to some maxillopalatine

Changes for: anatomical line between outer canthi

Deleted
- - anatomical line between outer canthi EquivalentTo anatomical line and part of some face and connects some right outer canthus and connects some left outer canthus
- - anatomical line between outer canthi SubClassOf connects some left outer canthus
- - anatomical line between outer canthi SubClassOf connects some right outer canthus
Added
- + anatomical line between outer canthi EquivalentTo anatomical line and part of some face and connects some right outer canthus and connects some left outer canthus
- + anatomical line between outer canthi SubClassOf connects some left outer canthus
- + anatomical line between outer canthi SubClassOf connects some right outer canthus

Changes for: duodenal gland

Deleted
- - duodenal gland comment Editor note: currently defined as equivalent to any submucosal gland in the duodenum. Taxon notes: Said to be absent outside mammlian (Andrew 1959) but Ziswiler and Farner (1972) noted similar glands at the gastroduodenal junction of some birds [ISBN:9780521617147]
Added
- + duodenal gland editor note currently defined as equivalent to any submucosal gland in the duodenum. Taxon notes: Said to be absent outside mammlian (Andrew 1959) but Ziswiler and Farner (1972) noted similar glands at the gastroduodenal junction of some birds [ISBN:9780521617147]

Changes for: intestinal villus

Deleted
- - intestinal villus comment Editor notes: in mammals, villi are (largely?) absent from the large intestine, so we treat this as equivalent to small intestinal villus. small/large subdivision may not make sense for all speciesi for which this is present (see ZFA). Note that VHOG quotes ISBN:978-0030223693 as suggesting there are some villi in the large intestine. AO Notes: the BTO class refers to a generic villous
Added
- + intestinal villus comment AO Notes: the BTO class refers to a generic villous
- + intestinal villus editor note in mammals, villi are (largely?) absent from the large intestine, so we treat this as equivalent to small intestinal villus. small/large subdivision may not make sense for all speciesi for which this is present (see ZFA). Note that VHOG quotes ISBN:978-0030223693 as suggesting there are some villi in the large intestine

Changes for: hypothalamo-hypophyseal system

Deleted
- - hypothalamo-hypophyseal system SubClassOf connects some adenohypophysis
- - hypothalamo-hypophyseal system SubClassOf connects some hypothalamus
- - hypothalamo-hypophyseal system SubClassOf connects some median eminence of neurohypophysis
Added
- + hypothalamo-hypophyseal system SubClassOf connects some adenohypophysis
- + hypothalamo-hypophyseal system SubClassOf connects some hypothalamus
- + hypothalamo-hypophyseal system SubClassOf connects some median eminence of neurohypophysis

Changes for: epithelium of pancreatic duct

Deleted
- - epithelium of pancreatic duct comment Editor note: in EHDAA2, the embryonic pancreatic ducts (dorsal, ventral) are classified as eithelial sacs, which would render them subclasses this
Added
- + epithelium of pancreatic duct editor note in EHDAA2, the embryonic pancreatic ducts (dorsal, ventral) are classified as eithelial sacs, which would render them subclasses this

Changes for: ureterovesical junction

Deleted
- - ureterovesical junction EquivalentTo anatomical junction and connects some ureter and connects some urinary bladder
- - ureterovesical junction SubClassOf connects some ureter
- - ureterovesical junction SubClassOf connects some urinary bladder
Added
- + ureterovesical junction EquivalentTo anatomical junction and connects some ureter and connects some urinary bladder
- + ureterovesical junction SubClassOf connects some ureter
- + ureterovesical junction SubClassOf connects some urinary bladder

Changes for: ureteropelvic junction

Deleted
- - ureteropelvic junction EquivalentTo anatomical junction and connects some ureter and connects some renal pelvis
- - ureteropelvic junction SubClassOf connects some renal pelvis
- - ureteropelvic junction SubClassOf connects some ureter
Added
- + ureteropelvic junction EquivalentTo anatomical junction and connects some ureter and connects some renal pelvis
- + ureteropelvic junction SubClassOf connects some renal pelvis
- + ureteropelvic junction SubClassOf connects some ureter

Changes for: mesenchyme of umbilical cord

Added
- + mesenchyme of umbilical cord SubClassOf extraembryonic tissue

Changes for: gonadal fat pad

Deleted
- - gonadal fat pad comment Editor notes: consider change relationship from part_of. AO notes: we place the amphibian structures here as their definitions state a gonadal association.
Added
- + gonadal fat pad comment AO notes: we place the amphibian structures here as their definitions state a gonadal association.
- + gonadal fat pad editor note consider change relationship from part_of

Changes for: stato-acoustic epithelium

Deleted
- - stato-acoustic epithelium comment Editor note: required by CL
Added
- + stato-acoustic epithelium editor note required by CL

Changes for: antennal gland

Deleted
- - antennal gland comment Editor note: consider also classifying this as a renal tubule - or separate terms for coiled/nephridial canal. Editor note: cede this term to Arthropod AO
Added
- + antennal gland comment Editor note: cede this term to Arthropod AO
- + antennal gland editor note consider also classifying this as a renal tubule - or separate terms for coiled/nephridial canal

Changes for: vomeronasal system

Deleted
- - vomeronasal system comment Editor note: check relationship to olfactory system. Evolution: The morphological components of the VNS are found only in tetrapods, but the genetic components of the system have been found in teleost fish, in addition to tetrapods. In tetrapods, the VNS was thought to be the olfactory system for detecting pheromones, while the main olfactory system detected general odorants (Scalia and Winans 1975). However, experimental evidence suggests that there is not such a clear functional distinction (Restrepo et al. 2004; Baxi, Dorries, and Eisthen 2006; Spehr et al. 2006; Kelliher 2007). Sea lampreys produce unique bile acids which act as pheromones both in migration and mate finding (Li, Sorensen, and Gallaher 1995; Li et al. 2002; Siefkes and Li 2004). However, bile acids in teleost fish are known to require components of the main olfactory signal transduction pathway (Hansen et al. 2003), and interruption of the VNS signal transduction pathway had no effect on bile acid olfactory response (Hansen et al. 2003)[Grus - EVOLUTION OF THE VOMERONASAL SYSTEM VIEWED THROUGH SYSTEM-SPECIFIC GENES]
Added
- + vomeronasal system editor note check relationship to olfactory system. Evolution: The morphological components of the VNS are found only in tetrapods, but the genetic components of the system have been found in teleost fish, in addition to tetrapods. In tetrapods, the VNS was thought to be the olfactory system for detecting pheromones, while the main olfactory system detected general odorants (Scalia and Winans 1975). However, experimental evidence suggests that there is not such a clear functional distinction (Restrepo et al. 2004; Baxi, Dorries, and Eisthen 2006; Spehr et al. 2006; Kelliher 2007). Sea lampreys produce unique bile acids which act as pheromones both in migration and mate finding (Li, Sorensen, and Gallaher 1995; Li et al. 2002; Siefkes and Li 2004). However, bile acids in teleost fish are known to require components of the main olfactory signal transduction pathway (Hansen et al. 2003), and interruption of the VNS signal transduction pathway had no effect on bile acid olfactory response (Hansen et al. 2003)[Grus - EVOLUTION OF THE VOMERONASAL SYSTEM VIEWED THROUGH SYSTEM-SPECIFIC GENES]

Changes for: tibiotalar joint

Deleted
- - tibiotalar joint EquivalentTo skeletal joint and connects some tibia and connects some talus
- - tibiotalar joint SubClassOf connects some talus
- - tibiotalar joint SubClassOf connects some tibia
Added
- + tibiotalar joint EquivalentTo skeletal joint and connects some tibia and connects some talus
- + tibiotalar joint SubClassOf connects some talus
- + tibiotalar joint SubClassOf connects some tibia

Changes for: adenohypophyseal placode

Deleted
- - adenohypophyseal placode comment Editor notes: consider adding more detailed spatial placement - e.g. oral ectoderm and/or rostal ectoderm. Addtional notes: Fate-mapping studies in amphibian, chick and mouse embryos (Eagleson et al., 1986; 1995; Couly and Le Douarin, 1985; Cobos et al., 2001; Osumi-Yamachita et al., 1994; Kawamura et al., 2002) have shown that the cells contributing to the adenohypophysis develop at the midline of the anterior neural ridge, which delineates the rostral boundary of the neural plate, a region devoid of neural crest. The anterior neural ridge also gives rise to the olfactory placodes and some forebrain tissues including the olfactory bulbs (reviewed in Papalopulu, 1995). Ablation of this region in chick embryos at the 2-4 somite stage confirmed these lineage analyses as it prevented formation of Rathke’s pouch and any further pituitary development (elAmraoui and Dubois, 1993). Upon head folding, the oral ectoderm cells of the adenohypophyseal placode invaginate towards the prospective ventral diencephalon to form Rathke’s pouch, the anlage of the adenohypophysis. Rathke’s pouch starts as an invagination of the oral ectoderm in response to inductive signals from the prospective diencephalon. The region of the diencephalon above the pouch is known as the infundibulum and forms the posterior lobe of the pituitary or neurohypohysis (Figure 3). While in most basal fish and tetrapods the adenohypophyseal anlagen invaginates to form Rathke’s pouch, in teleost fish the adenohypophyseal placode does not invaginate but rather maintains its initial organization forming a solid structure in the head (reviewed in Pogoda and Hammerschmidt; 2009)
Added
- + adenohypophyseal placode comment Addtional notes: Fate-mapping studies in amphibian, chick and mouse embryos (Eagleson et al., 1986; 1995; Couly and Le Douarin, 1985; Cobos et al., 2001; Osumi-Yamachita et al., 1994; Kawamura et al., 2002) have shown that the cells contributing to the adenohypophysis develop at the midline of the anterior neural ridge, which delineates the rostral boundary of the neural plate, a region devoid of neural crest. The anterior neural ridge also gives rise to the olfactory placodes and some forebrain tissues including the olfactory bulbs (reviewed in Papalopulu, 1995). Ablation of this region in chick embryos at the 2-4 somite stage confirmed these lineage analyses as it prevented formation of Rathke’s pouch and any further pituitary development (elAmraoui and Dubois, 1993). Upon head folding, the oral ectoderm cells of the adenohypophyseal placode invaginate towards the prospective ventral diencephalon to form Rathke’s pouch, the anlage of the adenohypophysis. Rathke’s pouch starts as an invagination of the oral ectoderm in response to inductive signals from the prospective diencephalon. The region of the diencephalon above the pouch is known as the infundibulum and forms the posterior lobe of the pituitary or neurohypohysis (Figure 3). While in most basal fish and tetrapods the adenohypophyseal anlagen invaginates to form Rathke’s pouch, in teleost fish the adenohypophyseal placode does not invaginate but rather maintains its initial organization forming a solid structure in the head (reviewed in Pogoda and Hammerschmidt; 2009)
- + adenohypophyseal placode editor note consider adding more detailed spatial placement - e.g. oral ectoderm and/or rostal ectoderm

Changes for: cranial sensory ganglion

Deleted
- - cranial sensory ganglion comment Editor note: check this - merge into cranial ganglion? WP: the geniculate, petrosal and nodose ganglia, appended respectively to cranial nerves VII, IX and X. Other ontology notes: has no subtypes in FMA
Added
- + cranial sensory ganglion editor note check this - merge into cranial ganglion? WP: the geniculate, petrosal and nodose ganglia, appended respectively to cranial nerves VII, IX and X. Other ontology notes: has no subtypes in FMA

Changes for: vestibulocochlear ganglion

Deleted
- - vestibulocochlear ganglion comment Editor notes: Consider follow MA naming scheme. // The cell bodies of the cochlear nerve lie within the central aspect of the cochlea and are collectively known as the spiral ganglion. This name reflects the fact that the cell bodies, considered as a unit, have a spiral (or perhaps more accurately, a helical) shape, reflecting the shape of the cochlea. The terms “cochlear nerve fiber” and “spiral ganglion cell” are used, to some degree, interchangeably, although the former may be used to more specifically refer to the central axons of the cochlear nerve. These central axons exit the cochlea at its base, where it forms a nerve trunk. In humans, this aspect of the nerve is roughly one inch in length. It projects centrally to the brainstem, where its fibers synapse with the cell bodies of the cochlear nucleus[Wikipedia:Cochlear_nerve]
Added
- + vestibulocochlear ganglion comment The cell bodies of the cochlear nerve lie within the central aspect of the cochlea and are collectively known as the spiral ganglion. This name reflects the fact that the cell bodies, considered as a unit, have a spiral (or perhaps more accurately, a helical) shape, reflecting the shape of the cochlea. The terms “cochlear nerve fiber” and “spiral ganglion cell” are used, to some degree, interchangeably, although the former may be used to more specifically refer to the central axons of the cochlear nerve. These central axons exit the cochlea at its base, where it forms a nerve trunk. In humans, this aspect of the nerve is roughly one inch in length. It projects centrally to the brainstem, where its fibers synapse with the cell bodies of the cochlear nucleus[Wikipedia:Cochlear_nerve]
- + vestibulocochlear ganglion editor note Consider follow MA naming scheme.

Changes for: shoulder bone

Deleted
- - shoulder bone EquivalentTo bone element and part of some shoulder
- - shoulder bone SubClassOf part of some pectoral girdle skeleton
- - shoulder bone SubClassOf part of some shoulder
- - shoulder bone SubClassOf pectoral girdle bone
- - shoulder bone comment AO notes: this is a forelimb bone in MA, but this would lead to part-disjointness violations. Subtypes are clavicle, scapula, humerus
- - shoulder bone definition A bone that is part of a shoulder [Automatically generated definition]. { database cross reference=OBOL:automatic }
- - shoulder bone has exact synonym bone organ of shoulder { database cross reference=OBOL:automatic }
- - shoulder bone has exact synonym shoulder bone organ { database cross reference=OBOL:automatic }
Added
- + shoulder bone EquivalentTo bone element and has part some part of some shoulder joint
- + shoulder bone SubClassOf bone of pectoral complex
- + shoulder bone SubClassOf has part some part of some shoulder joint
- + shoulder bone SubClassOf part of some skeleton of pectoral complex
- + shoulder bone comment AO notes: this is a forelimb bone in MA, but this would lead to part-disjointness violations.
- + shoulder bone definition A bone that is connected via a shoulder joint (i.e. glenohumeral or acromioclavicular joints). The shoulder bones are the clavicle, scapula and humerus - but note that these are only considered to be shoulder bones when a true shoulder is present, as in most tetrapods. { database cross reference=UBERON:cjm }
- + shoulder bone has exact synonym shoulder-articulating bone

Changes for: thoracic cavity nerve

Deleted
- - thoracic cavity nerve comment Editor note: consider merging with thoracic nerve. In MA the only subclass is the phrenic nerve, which arises from a cervical nerve
Added
- + thoracic cavity nerve editor note consider merging with thoracic nerve. In MA the only subclass is the phrenic nerve, which arises from a cervical nerve

Changes for: upper jaw incisor

Deleted
- - upper jaw incisor SubClassOf tooth of upper jaw
Added
- + upper jaw incisor SubClassOf premaxillary tooth

Changes for: facial suture

Deleted
- - facial suture EquivalentTo craniofacial suture and ObjectMinCardinality( connects facial bone ) and ObjectMaxCardinality( connects facial bone )
- - facial suture SubClassOf connects some facial bone
Added
- + facial suture EquivalentTo craniofacial suture and ObjectMinCardinality( connects facial bone ) and ObjectMaxCardinality( connects facial bone )
- + facial suture SubClassOf connects some facial bone

Changes for: craniofacial suture

Deleted
- - craniofacial suture comment Editor notes: we follow GO in dividing sutures into cranial and facial and making a grouping class, but this is not consistent with FMA
Added
- + craniofacial suture editor note we follow GO in dividing sutures into cranial and facial and making a grouping class, but this is not consistent with FMA

Changes for: costochondral joint

Deleted
- - costochondral joint SubClassOf connects some costal cartilage
- - costochondral joint SubClassOf connects some distal segment of rib
Added
- + costochondral joint SubClassOf connects some costal cartilage
- + costochondral joint SubClassOf connects some distal segment of rib

Changes for: costovertebral joint

Deleted
- - costovertebral joint EquivalentTo skeletal joint and connects some head of rib and connects some thoracic vertebra
- - costovertebral joint SubClassOf connects some head of rib
- - costovertebral joint SubClassOf connects some thoracic vertebra
Added
- + costovertebral joint EquivalentTo skeletal joint and connects some head of rib and connects some thoracic vertebra
- + costovertebral joint SubClassOf connects some head of rib
- + costovertebral joint SubClassOf connects some thoracic vertebra

Changes for: foramen of Panizza

Deleted
- - foramen of Panizza SubClassOf ObjectMinCardinality( connects aorta ) and ObjectMaxCardinality( connects aorta )
- - foramen of Panizza SubClassOf connects some aorta
Added
- + foramen of Panizza SubClassOf ObjectMinCardinality( connects aorta ) and ObjectMaxCardinality( connects aorta )
- + foramen of Panizza SubClassOf connects some aorta

Changes for: accessory lacrimal gland

Deleted
- - accessory lacrimal gland comment Editor notes: may be re-classified as a sibling on lacrimal gland
Added
- + accessory lacrimal gland editor note may be re-classified as a sibling on lacrimal gland

Changes for: tubercle of rib

Deleted
- - tubercle of rib SubClassOf skeletal element projection
- - tubercle of rib SubClassOf tubercle
Added
- + tubercle of rib SubClassOf bony tubercle

Changes for: posttemporal-parietal joint

Deleted
- - posttemporal-parietal joint EquivalentTo skeletal joint and connects some actinopterygian parietal bone and connects some posttemporal
- - posttemporal-parietal joint SubClassOf connects some actinopterygian parietal bone
- - posttemporal-parietal joint SubClassOf connects some posttemporal
Added
- + posttemporal-parietal joint EquivalentTo skeletal joint and connects some actinopterygian parietal bone and connects some posttemporal
- + posttemporal-parietal joint SubClassOf connects some actinopterygian parietal bone
- + posttemporal-parietal joint SubClassOf connects some posttemporal

Changes for: vertebra 5-vertebra 6 joint

Deleted
- - vertebra 5-vertebra 6 joint EquivalentTo skeletal joint and connects some vertebral element 5 and connects some vertebral element 6
- - vertebra 5-vertebra 6 joint SubClassOf connects some vertebral element 5
- - vertebra 5-vertebra 6 joint SubClassOf connects some vertebral element 6
Added
- + vertebra 5-vertebra 6 joint EquivalentTo skeletal joint and connects some vertebral element 5 and connects some vertebral element 6
- + vertebra 5-vertebra 6 joint SubClassOf connects some vertebral element 5
- + vertebra 5-vertebra 6 joint SubClassOf connects some vertebral element 6

Changes for: vertebra 6 - vertebra 7 joint

Deleted
- - vertebra 6 - vertebra 7 joint EquivalentTo skeletal joint and connects some vertebral element 6 and connects some vertebral element 7
- - vertebra 6 - vertebra 7 joint SubClassOf connects some vertebral element 6
- - vertebra 6 - vertebra 7 joint SubClassOf connects some vertebral element 7
Added
- + vertebra 6 - vertebra 7 joint EquivalentTo skeletal joint and connects some vertebral element 6 and connects some vertebral element 7
- + vertebra 6 - vertebra 7 joint SubClassOf connects some vertebral element 6
- + vertebra 6 - vertebra 7 joint SubClassOf connects some vertebral element 7

Changes for: clavicle

Added
- + clavicle SubClassOf pectoral girdle bone

Changes for: lobe of liver

Deleted
- - lobe of liver comment editor note: some work needs to be done to ensure the child terms of this class have correct isa/partof placement. in MA they are subclasses, in FMA they are parts
Added
- + lobe of liver editor note some work needs to be done to ensure the child terms of this class have correct isa/partof placement. in MA they are subclasses, in FMA they are parts

Changes for: corpora quadrigemina

Deleted
- - corpora quadrigemina comment editor note: this section needs worked on for pan-vertebrate consistency. for now we include a mammal specific definition, even though the child terms are applicable across vertebrates
Added
- + corpora quadrigemina editor note this section needs worked on for pan-vertebrate consistency. for now we include a mammal specific definition, even though the child terms are applicable across vertebrates

Changes for: lateral ethmoid-frontal joint

Deleted
- - lateral ethmoid-frontal joint EquivalentTo skeletal joint and connects some actinopterygian frontal bone and connects some lateral ethmoid bone
- - lateral ethmoid-frontal joint SubClassOf connects some actinopterygian frontal bone
- - lateral ethmoid-frontal joint SubClassOf connects some lateral ethmoid bone
Added
- + lateral ethmoid-frontal joint EquivalentTo skeletal joint and connects some actinopterygian frontal bone and connects some lateral ethmoid bone
- + lateral ethmoid-frontal joint SubClassOf connects some actinopterygian frontal bone
- + lateral ethmoid-frontal joint SubClassOf connects some lateral ethmoid bone

Changes for: prootic-pterosphenoid joint

Deleted
- - prootic-pterosphenoid joint EquivalentTo skeletal joint and connects some prootic bone and connects some pterosphenoid
- - prootic-pterosphenoid joint SubClassOf connects some prootic bone
- - prootic-pterosphenoid joint SubClassOf connects some pterosphenoid
Added
- + prootic-pterosphenoid joint EquivalentTo skeletal joint and connects some prootic bone and connects some pterosphenoid
- + prootic-pterosphenoid joint SubClassOf connects some prootic bone
- + prootic-pterosphenoid joint SubClassOf connects some pterosphenoid

Changes for: prootic-exoccipital joint

Deleted
- - prootic-exoccipital joint EquivalentTo skeletal joint and connects some exoccipital bone and connects some prootic bone
- - prootic-exoccipital joint SubClassOf connects some exoccipital bone
- - prootic-exoccipital joint SubClassOf connects some prootic bone
Added
- + prootic-exoccipital joint EquivalentTo skeletal joint and connects some exoccipital bone and connects some prootic bone
- + prootic-exoccipital joint SubClassOf connects some exoccipital bone
- + prootic-exoccipital joint SubClassOf connects some prootic bone

Changes for: basioccipital-exoccipital joint

Deleted
- - basioccipital-exoccipital joint EquivalentTo skeletal joint and connects some basioccipital bone and connects some exoccipital bone
- - basioccipital-exoccipital joint SubClassOf connects some basioccipital bone
- - basioccipital-exoccipital joint SubClassOf connects some exoccipital bone
Added
- + basioccipital-exoccipital joint EquivalentTo skeletal joint and connects some basioccipital bone and connects some exoccipital bone
- + basioccipital-exoccipital joint SubClassOf connects some basioccipital bone
- + basioccipital-exoccipital joint SubClassOf connects some exoccipital bone

Changes for: sternocleidomastoid

Deleted
- - sternocleidomastoid comment Editor notes: TODO: sternocleidomastoid = sternomastoid + Cleidomastoideus. Origin: from manubrium sterni (sterno) and clavicle (cleido) and it’s insertion at the mastoid process of the temporal bone.
Added
- + sternocleidomastoid editor note TODO: sternocleidomastoid = sternomastoid + Cleidomastoideus. Origin: from manubrium sterni (sterno) and clavicle (cleido) and it’s insertion at the mastoid process of the temporal bone.

Changes for: vertebral column

Deleted
- - vertebral column comment Editor notes: Note that in contrast to VSAO, this is a subset of the skeletal system, and thus includes intervertebral joints, cartilage and ligaments etc. Some ontologies such as AAO seem to purely refer to the skeleton
Added
- + vertebral column editor note Note that in contrast to VSAO, this is a subset of the skeletal system, and thus includes intervertebral joints, cartilage and ligaments etc. Some ontologies such as AAO seem to purely refer to the skeleton

Changes for: musculoskeletal system

Added
- + musculoskeletal system SubClassOf existence ends during some fully formed stage

Changes for: subfornical organ

Deleted
- - subfornical organ comment Function notes: induces drinking behavior after stimulation with angiotensin II[MESH].
Added
- + subfornical organ function notes induces drinking behavior after stimulation with angiotensin II[MESH].

Changes for: cardia of stomach

Deleted
- - cardia of stomach comment Editor notes: We follow Kardong in defining stomach regions by glands. Boundary notes: There were previously conflicting statements in the academic anatomy community[10][11][12] over whether the cardia is part of the stomach, part of the esophagus or a distinct entity. Modern surgical and medical textbooks have agreed that “The gastric cardia is now clearly considered to be part of the stomach”[13][14]. Classical anatomy textbooks, and some other resources[15], describe the cardia as the first of 4 regions of the stomach. This makes sense histologically because the mucosa of the cardia is the same as that of the stomach[WP].
Added
- + cardia of stomach comment Boundary notes: There were previously conflicting statements in the academic anatomy community[10][11][12] over whether the cardia is part of the stomach, part of the esophagus or a distinct entity. Modern surgical and medical textbooks have agreed that “The gastric cardia is now clearly considered to be part of the stomach”[13][14]. Classical anatomy textbooks, and some other resources[15], describe the cardia as the first of 4 regions of the stomach. This makes sense histologically because the mucosa of the cardia is the same as that of the stomach[WP]
- + cardia of stomach editor note We follow Kardong in defining stomach regions by glands.

Changes for: pylorus

Deleted
- - pylorus comment Editor notes: We follow Kardong in defining stomach regions by glands
Added
- + pylorus editor note We follow Kardong in defining stomach regions by glands

Changes for: extraembryonic umbilical vein

Added
- + extraembryonic umbilical vein SubClassOf extraembryonic structure

Changes for: renal artery

Deleted
- - renal artery comment Editor notes: renal arteries vary widely even in humans. Sub-structures should be checked for taxon variability.
Added
- + renal artery editor note renal arteries vary widely even in humans. Sub-structures should be checked for taxon variability.

Changes for: joint of girdle

Deleted
- - joint of girdle SubClassOf connects some girdle bone/zone
Added
- + joint of girdle SubClassOf connects some girdle bone/zone

Changes for: internasal suture

Deleted
- - internasal suture EquivalentTo facial suture and ObjectMinCardinality( connects nasal bone ) and ObjectMaxCardinality( connects nasal bone )
- - internasal suture SubClassOf connects some nasal bone
Added
- + internasal suture EquivalentTo facial suture and ObjectMinCardinality( connects nasal bone ) and ObjectMaxCardinality( connects nasal bone )
- + internasal suture SubClassOf connects some nasal bone

Changes for: internal naris

Added
- + internal naris has exact synonym internal choana

Changes for: superior cerebellar peduncle

Deleted
- - superior cerebellar peduncle comment Editor notes: we follow NIF in dividing this into 3 parts. This allows for consistency with ABA. AO notes: we make the TAO class disjoint for now as it’s not clear if this is the analagous structure
Added
- + superior cerebellar peduncle comment AO notes: we make the TAO class disjoint for now as it’s not clear if this is the analagous structure
- + superior cerebellar peduncle editor note we follow NIF in dividing this into 3 parts. This allows for consistency with ABA

Changes for: area postrema

Deleted
- - area postrema comment Function notes: vomiting center in humans[WP]
Added
- + area postrema function notes vomiting center in humans[WP]

Changes for: atrioventricular valve

Deleted
- - atrioventricular valve SubClassOf connects some cardiac atrium
- - atrioventricular valve SubClassOf connects some cardiac ventricle
Added
- + atrioventricular valve SubClassOf connects some cardiac atrium
- + atrioventricular valve SubClassOf connects some cardiac ventricle

Changes for: tricuspid valve

Deleted
- - tricuspid valve SubClassOf connects some heart right ventricle
- - tricuspid valve SubClassOf connects some right cardiac atrium
Added
- + tricuspid valve SubClassOf connects some heart right ventricle
- + tricuspid valve SubClassOf connects some right cardiac atrium

Changes for: mitral valve

Deleted
- - mitral valve SubClassOf connects some heart left ventricle
- - mitral valve SubClassOf connects some left cardiac atrium
Added
- + mitral valve SubClassOf connects some heart left ventricle
- + mitral valve SubClassOf connects some left cardiac atrium

Changes for: respiratory system

Added
- + respiratory system SubClassOf existence ends during some fully formed stage

Changes for: renal system

Added
- + renal system SubClassOf existence ends during some fully formed stage

Changes for: circulatory system

Added
- + circulatory system SubClassOf existence ends during some fully formed stage
- + circulatory system dubious for taxon http://purl.obolibrary.org/obo/NCBITaxon_6231 { notes=WBbt coelomocyte currently classified as circulating cell }

Changes for: digestive system

Added
- + digestive system SubClassOf existence ends during some fully formed stage

Changes for: nervous system

Added
- + nervous system SubClassOf existence ends during some fully formed stage

Changes for: midgut

Deleted
- - midgut comment Editor notes: Note we define this generically to include invertebrates (partly for consistency with GO), but the class may be split in future. We may explicitly make this a developmental class. AO Notes: in FMA this class has no children.
Added
- + midgut comment AO Notes: in FMA this class has no children.
- + midgut editor note Note we define this generically to include invertebrates (partly for consistency with GO), but the class may be split in future. We may explicitly make this a developmental class

Changes for: hindgut

Deleted
- - hindgut comment Editor notes: Note we define this generically to include invertebrates (partly for consistency with GO), but the class may be split in future (vertebrates have some contribution from NC - UBERONREF:0000002). We may explicitly make this a developmental class. AO Notes: in FMA this class has no children.
Added
- + hindgut comment AO Notes: in FMA this class has no children.
- + hindgut editor note Note we define this generically to include invertebrates (partly for consistency with GO), but the class may be split in future (vertebrates have some contribution from NC - UBERONREF:0000002). We may explicitly make this a developmental class

Changes for: foregut

Deleted
- - foregut comment Editor notes: Note we define this generically to include invertebrates (partly for consistency with GO), but the class may be split in future. In vertebrates the term may refer to a developmental structure
Added
- + foregut editor note Note we define this generically to include invertebrates (partly for consistency with GO), but the class may be split in future. In vertebrates the term may refer to a developmental structure

Changes for: limb

Added
- + limb SubClassOf existence ends during some fully formed stage

Changes for: Malpighian tubule

Deleted
- - Malpighian tubule comment Editor note: this will be ceded to the Arthropod Anatomy Ontology
Added
- + Malpighian tubule editor note this will be ceded to the Arthropod Anatomy Ontology

Changes for: pneumatized bone

Deleted
- - pneumatized bone comment editor note: subclasses of this should be checked for taxonomic consistency
Added
- + pneumatized bone editor note subclasses of this should be checked for taxonomic consistency

Changes for: dento-alveolar joint

Deleted
- - dento-alveolar joint SubClassOf connects some alveolar ridge
- - dento-alveolar joint SubClassOf connects some calcareous tooth
Added
- + dento-alveolar joint SubClassOf connects some alveolar ridge
- + dento-alveolar joint SubClassOf connects some calcareous tooth

Changes for: gustatory system

Added
- + gustatory system SubClassOf existence ends during some fully formed stage

Changes for: flocculus

Added
- + flocculus database cross reference http://www.snomedbrowser.com/Codes/Details/279368002

Changes for: vertebral arch joint

Deleted
- - vertebral arch joint EquivalentTo synovial joint and connects some prezygapophysis and connects some postzygapophysis
- - vertebral arch joint SubClassOf connects some postzygapophysis
- - vertebral arch joint SubClassOf connects some prezygapophysis
Added
- + vertebral arch joint EquivalentTo synovial joint and connects some prezygapophysis and connects some postzygapophysis
- + vertebral arch joint SubClassOf connects some postzygapophysis
- + vertebral arch joint SubClassOf connects some prezygapophysis

Changes for: ileocecal junction

Deleted
- - ileocecal junction EquivalentTo anatomical junction and connects some large intestine and connects some small intestine
- - ileocecal junction SubClassOf connects some large intestine
- - ileocecal junction SubClassOf connects some small intestine
Added
- + ileocecal junction EquivalentTo anatomical junction and connects some large intestine and connects some small intestine
- + ileocecal junction SubClassOf connects some large intestine
- + ileocecal junction SubClassOf connects some small intestine

Changes for: anterolateral ligament of knee

Deleted
- - anterolateral ligament of knee SubClassOf connects some lateral epicondyle of femur
- - anterolateral ligament of knee SubClassOf connects some tibia
Added
- + anterolateral ligament of knee SubClassOf connects some lateral epicondyle of femur
- + anterolateral ligament of knee SubClassOf connects some tibia

Changes for: neural spine

Deleted
- - neural spine comment Editor notes: todo - reconcile AAO def: “Small, posteriorly directed process at the posterior margin of each neural arch lamina; it is not a neural spine.” [AAO:0000739]
- - neural spine database cross reference AAO:0000739

Changes for: water vascular system

Added
- + water vascular system SubClassOf existence ends during some fully formed stage

Changes for: mesenchyme from somatopleure

Deleted
- - mesenchyme from somatopleure comment Editor notes: the way this class is defined also includes extraembryonic mesenchyme such as the amniotic mesenchyme; in future this may be restricted to embryonic derivatives
Added
- + mesenchyme from somatopleure editor note the way this class is defined also includes extraembryonic mesenchyme such as the amniotic mesenchyme; in future this may be restricted to embryonic derivatives

Changes for: intercerebral commissure

Deleted
- - intercerebral commissure EquivalentTo nervous system commissure and connects some left cerebral hemisphere and connects some right cerebral hemisphere
- - intercerebral commissure SubClassOf connects some left cerebral hemisphere
- - intercerebral commissure SubClassOf connects some right cerebral hemisphere
Added
- + intercerebral commissure EquivalentTo nervous system commissure and connects some left cerebral hemisphere and connects some right cerebral hemisphere
- + intercerebral commissure SubClassOf connects some left cerebral hemisphere
- + intercerebral commissure SubClassOf connects some right cerebral hemisphere

Changes for: extraembryonic membrane mesenchyme

Added
- + extraembryonic membrane mesenchyme SubClassOf extraembryonic tissue

Changes for: coronal suture

Deleted
- - coronal suture EquivalentTo cranial suture and connects some tetrapod frontal bone and connects some tetrapod parietal bone
- - coronal suture SubClassOf connects some tetrapod frontal bone
- - coronal suture SubClassOf connects some tetrapod parietal bone
Added
- + coronal suture EquivalentTo cranial suture and connects some tetrapod frontal bone and connects some tetrapod parietal bone
- + coronal suture SubClassOf connects some tetrapod frontal bone
- + coronal suture SubClassOf connects some tetrapod parietal bone

Changes for: bregma

Deleted
- - bregma SubClassOf connects some coronal suture
- - bregma SubClassOf connects some sagittal suture
Added
- + bregma SubClassOf connects some coronal suture
- + bregma SubClassOf connects some sagittal suture

Changes for: deltopectoral crest

Deleted
- - deltopectoral crest SubClassOf skeletal element projection
- - deltopectoral crest SubClassOf tubercle
Added
- + deltopectoral crest SubClassOf bony tubercle

Changes for: cochlear labyrinth

Deleted
- - cochlear labyrinth comment Editor notes: we follow the FMA in placing this in the membranous labyrinth. Notes: The labyrinth can be divided by layer or by region. Bony vs. membranous / Vestibular vs. cochlear
Added
- + cochlear labyrinth editor note we follow the FMA in placing this in the membranous labyrinth. Notes: The labyrinth can be divided by layer or by region. Bony vs. membranous / Vestibular vs. cochlear

Changes for: frontal suture

Deleted
- - frontal suture EquivalentTo cranial suture and ObjectMinCardinality( connects tetrapod frontal bone ) and ObjectMaxCardinality( connects tetrapod frontal bone )
- - frontal suture SubClassOf connects some tetrapod frontal bone
Added
- + frontal suture EquivalentTo cranial suture and ObjectMinCardinality( connects tetrapod frontal bone ) and ObjectMaxCardinality( connects tetrapod frontal bone )
- + frontal suture SubClassOf connects some tetrapod frontal bone

Changes for: lambdoid suture

Deleted
- - lambdoid suture EquivalentTo cranial suture and connects some tetrapod parietal bone and connects some occipital bone and connects some temporal bone
- - lambdoid suture SubClassOf connects some occipital bone
- - lambdoid suture SubClassOf connects some temporal bone
- - lambdoid suture SubClassOf connects some tetrapod parietal bone
Added
- + lambdoid suture EquivalentTo cranial suture and connects some tetrapod parietal bone and connects some occipital bone and connects some temporal bone
- + lambdoid suture SubClassOf connects some occipital bone
- + lambdoid suture SubClassOf connects some temporal bone
- + lambdoid suture SubClassOf connects some tetrapod parietal bone

Changes for: sagittal suture

Deleted
- - sagittal suture EquivalentTo cranial suture and ObjectMinCardinality( connects tetrapod parietal bone ) and ObjectMaxCardinality( connects tetrapod parietal bone )
- - sagittal suture SubClassOf connects some tetrapod parietal bone
Added
- + sagittal suture EquivalentTo cranial suture and ObjectMinCardinality( connects tetrapod parietal bone ) and ObjectMaxCardinality( connects tetrapod parietal bone )
- + sagittal suture SubClassOf connects some tetrapod parietal bone

Changes for: preopercle-opercle joint

Deleted
- - preopercle-opercle joint EquivalentTo skeletal joint and connects some opercle and connects some preopercle
- - preopercle-opercle joint SubClassOf connects some opercle
- - preopercle-opercle joint SubClassOf connects some preopercle
Added
- + preopercle-opercle joint EquivalentTo skeletal joint and connects some opercle and connects some preopercle
- + preopercle-opercle joint SubClassOf connects some opercle
- + preopercle-opercle joint SubClassOf connects some preopercle

Changes for: os sesamoides tarsale

Added
- + os sesamoides tarsale SubClassOf intertarsal sesamoid

Changes for: extraembryonic epithelium

Added
- + extraembryonic epithelium SubClassOf extraembryonic tissue

Changes for: supracondyle tubercle

Deleted
- - supracondyle tubercle SubClassOf skeletal element projection
- - supracondyle tubercle SubClassOf tubercle
Added
- + supracondyle tubercle SubClassOf bony tubercle

Changes for: bicipital tuberosity

Deleted
- - bicipital tuberosity SubClassOf skeletal element projection
- - bicipital tuberosity SubClassOf tubercle
Added
- + bicipital tuberosity SubClassOf bony tubercle

Changes for: lateral tubercle of astragalus

Deleted
- - lateral tubercle of astragalus SubClassOf skeletal element projection
- - lateral tubercle of astragalus SubClassOf tubercle
Added
- + lateral tubercle of astragalus SubClassOf bony tubercle

Changes for: ulnar tuberosity

Deleted
- - ulnar tuberosity SubClassOf skeletal element projection
- - ulnar tuberosity SubClassOf tubercle
Added
- + ulnar tuberosity SubClassOf bony tubercle

Changes for: muscularis orbicularis

Deleted
- - muscularis orbicularis comment Function notes: Hedgehogs roll into a ball via contraction of this muscle
Added
- + muscularis orbicularis function notes Hedgehogs roll into a ball via contraction of this muscle

Changes for: immune system

Added
- + immune system SubClassOf existence ends during some fully formed stage

Changes for: vertebra

Deleted
- - vertebra comment Editor notes: Consider changing name to make distinction from inferred superclass ‘vertebral element’ clear // note we follow FMA in making this an irregular bone - however vertebra have ‘epiphyses’ which are currently classified as belonging to long bones
Added
- + vertebra comment note we follow FMA in making this an irregular bone - however vertebra have ‘epiphyses’ which are currently classified as belonging to long bones
- + vertebra editor note Consider changing name to make distinction from inferred superclass ‘vertebral element’ clear

Changes for: integumental system

Added
- + integumental system SubClassOf existence ends during some fully formed stage

Changes for: tail

Deleted
- - tail comment Editor notes: Note we also have a subclass post-anal tail, for the chordate specific structure. currently defined very generally, inclusive of caudal fin
Added
- + tail editor note Note we also have a subclass post-anal tail, for the chordate specific structure. currently defined very generally, inclusive of caudal fin

Changes for: basal ganglion

Deleted
- - basal ganglion comment Editor note: it is necessary to introduce two classes, one representing an individual basal ganglion, another representing the aggregate structure, in order to have consistent classification amongst AOs (e.g. in MA the aygdala is part of the BG, in FMA and BTO it is a subclass). Apart from achieving this consistency, the value of having two distinct classes is questionable, since the BG-plural is trivially the set of all BGs-singular. it would be better for all AOs to decide on one single way of doing this. Do not merge until this is done.
Added
- + basal ganglion editor note it is necessary to introduce two classes, one representing an individual basal ganglion, another representing the aggregate structure, in order to have consistent classification amongst AOs (e.g. in MA the aygdala is part of the BG, in FMA and BTO it is a subclass). Apart from achieving this consistency, the value of having two distinct classes is questionable, since the BG-plural is trivially the set of all BGs-singular. it would be better for all AOs to decide on one single way of doing this. Do not merge until this is done.

Changes for: hepatobiliary system

Added
- + hepatobiliary system SubClassOf existence ends during some fully formed stage

Changes for: oral epithelium

Deleted
- - oral epithelium comment Editor note: consider including separate class for developmental structure (adult human is stratified; in EHDAA2 is unilaminar). Development notes: the avian oral epithelium has the developmental capacity to initiate tooth developmental programs with underlying grafts of non-avian oral ectomesenchyme [PMID:16488870]
Added
- + oral epithelium editor note consider including separate class for developmental structure (adult human is stratified; in EHDAA2 is unilaminar). Development notes: the avian oral epithelium has the developmental capacity to initiate tooth developmental programs with underlying grafts of non-avian oral ectomesenchyme [PMID:16488870]

Changes for: distal sesamoid impar ligament

Deleted
- - distal sesamoid impar ligament SubClassOf connects some distal phalanx
- - distal sesamoid impar ligament SubClassOf connects some equine distal sesamoid
Added
- + distal sesamoid impar ligament SubClassOf connects some distal phalanx
- + distal sesamoid impar ligament SubClassOf connects some equine distal sesamoid

Changes for: pituitary stalk

Deleted
- - pituitary stalk SubClassOf connects some hypothalamus
- - pituitary stalk SubClassOf connects some neurohypophysis
Added
- + pituitary stalk SubClassOf connects some hypothalamus
- + pituitary stalk SubClassOf connects some neurohypophysis

Changes for: placenta junctional zone

Added
- + placenta junctional zone SubClassOf extraembryonic structure

Changes for: upper part of vagina

Deleted
- - upper part of vagina comment Editor notes: relationship to caudal Mullerian duct?
Added
- + upper part of vagina editor note relationship to caudal Mullerian duct?

Changes for: placental labyrinth vasculature

Added
- + placental labyrinth vasculature SubClassOf extraembryonic structure

Changes for: utricle duct

Deleted
- - utricle duct SubClassOf connects some endolymphatic duct
- - utricle duct SubClassOf connects some utricle of membranous labyrinth
Added
- + utricle duct SubClassOf connects some endolymphatic duct
- + utricle duct SubClassOf connects some utricle of membranous labyrinth

Changes for: saccule duct

Deleted
- - saccule duct SubClassOf connects some endolymphatic duct
- - saccule duct SubClassOf connects some saccule of membranous labyrinth
Added
- + saccule duct SubClassOf connects some endolymphatic duct
- + saccule duct SubClassOf connects some saccule of membranous labyrinth

Changes for: anterior meningeal artery

Deleted
- - anterior meningeal artery comment Editor notes: this needs checking as part of a general revision of the blood vessels and their branches - unclear if the anterior meningeal artery should be treated separately from the anterior ethmoidal artery (ie as a branch) or the same thing
Added
- + anterior meningeal artery editor note this needs checking as part of a general revision of the blood vessels and their branches - unclear if the anterior meningeal artery should be treated separately from the anterior ethmoidal artery (ie as a branch) or the same thing

Changes for: arthropod hepatopancreas

Deleted
- - arthropod hepatopancreas comment Editor notes: this term should be ceded to the arthropod anatomy ontology
Added
- + arthropod hepatopancreas editor note this term should be ceded to the arthropod anatomy ontology

Changes for: pharyngeal arch mesenchymal region

Deleted
- - pharyngeal arch mesenchymal region comment Editor notes: this represents a part of the entire arch mesenchyme (UBERON:0010046), and is therefore a superclass of the individual arch mesenchyme classes. Alternate definition: primordial embryonic connective tissue associated with the branchial arches, consisting of mesenchymal cells supported in interlaminar jelly, that derive mostly from the mesoderm and contribute to facial and cranial nerve-associated structures. [MP:0011262]
Added
- + pharyngeal arch mesenchymal region editor note this represents a part of the entire arch mesenchyme (UBERON:0010046), and is therefore a superclass of the individual arch mesenchyme classes. Alternate definition: primordial embryonic connective tissue associated with the branchial arches, consisting of mesenchymal cells supported in interlaminar jelly, that derive mostly from the mesoderm and contribute to facial and cranial nerve-associated structures. [MP:0011262]

Changes for: mesocardium

Deleted
- - mesocardium comment Editor notes: consider merging with heart mesentery
Added
- + mesocardium editor note consider merging with heart mesentery

Changes for: placenta labyrinth

Added
- + placenta labyrinth SubClassOf extraembryonic structure

Changes for: anatomical line between outer ears

Deleted
- - anatomical line between outer ears SubClassOf connects some left external ear
- - anatomical line between outer ears SubClassOf connects some right external ear
Added
- + anatomical line between outer ears SubClassOf connects some left external ear
- + anatomical line between outer ears SubClassOf connects some right external ear

Changes for: squamoparietal suture

Deleted
- - squamoparietal suture EquivalentTo cranial suture and connects some tetrapod parietal bone and connects some squamous part of temporal bone
- - squamoparietal suture SubClassOf connects some squamous part of temporal bone
- - squamoparietal suture SubClassOf connects some tetrapod parietal bone
Added
- + squamoparietal suture EquivalentTo cranial suture and connects some tetrapod parietal bone and connects some squamous part of temporal bone
- + squamoparietal suture SubClassOf connects some squamous part of temporal bone
- + squamoparietal suture SubClassOf connects some tetrapod parietal bone

Changes for: spiral colon

Deleted
- - spiral colon comment Editor notes: Consider merging with ascending colon
Added
- + spiral colon editor note Consider merging with ascending colon

Changes for: anatomical line between pupils

Deleted
- - anatomical line between pupils SubClassOf connects some left pupil
- - anatomical line between pupils SubClassOf connects some right pupil
Added
- + anatomical line between pupils SubClassOf connects some left pupil
- + anatomical line between pupils SubClassOf connects some right pupil

Changes for: conducting system of heart

Deleted
- - conducting system of heart comment Editor notes: EHDAA2 divides the system from the tissue
Added
- + conducting system of heart editor note EHDAA2 divides the system from the tissue

Changes for: laryngeal apparatus

Deleted
- - laryngeal apparatus SubClassOf anatomical system
Added
- + laryngeal apparatus SubClassOf anatomical cluster

Changes for: meninx

Deleted
- - meninx comment Editor note: consider separate term for meninges aka collection of meninges. Note in EHDAA2 pia mater etc are part of the meninges. Also consider a new class for primary/primitive meninx. AO notes: Not consider part of the CNS/neuraxis in FMA. Taxon notes: Whereas cyclostomes and fishes only have a single envelope called the primitive meninx, amphibians have two layers, consisting of an outer dura mater which is extremely dense and protective, and a pia-arachnoid or secondary meninx which is more delicate and vascular. Mammals have three meninges: pia mater (which follows all the convolutions of the brain and is the most interior), the arachnoid layer (which is delicate and sends strands to the pia mater), and the dura mater (the outer, more protective meninx).
Added
- + meninx comment Taxon notes: Whereas cyclostomes and fishes only have a single envelope called the primitive meninx, amphibians have two layers, consisting of an outer dura mater which is extremely dense and protective, and a pia-arachnoid or secondary meninx which is more delicate and vascular. Mammals have three meninges: pia mater (which follows all the convolutions of the brain and is the most interior), the arachnoid layer (which is delicate and sends strands to the pia mater), and the dura mater (the outer, more protective meninx).
- + meninx editor note consider separate term for meninges aka collection of meninges. Note in EHDAA2 pia mater etc are part of the meninges. Also consider a new class for primary/primitive meninx. AO notes: Not consider part of the CNS/neuraxis in FMA

Changes for: pia mater

Deleted
- - pia mater comment Editor note: consider adding adjacency relationship to neuraxis (brain+spinal cord); however note that at this time the meninges may be considered part of the nervous system
Added
- + pia mater editor note consider adding adjacency relationship to neuraxis (brain+spinal cord); however note that at this time the meninges may be considered part of the nervous system

Changes for: dura mater

Deleted
- - dura mater comment Function notes: capable of inducing chondrogenesis - requires contact with an epithelium - http://www.ncbi.nlm.nih.gov/pubmed/16496288. AO notes: in ncit this is divided into periosteal layer and meningeal layer
Added
- + dura mater comment AO notes: in ncit this is divided into periosteal layer and meningeal layer
- + dura mater function notes capable of inducing chondrogenesis - requires contact with an epithelium - http://www.ncbi.nlm.nih.gov/pubmed/16496288

Changes for: mesencephalic vein

Deleted
- - mesencephalic vein comment Editor notes: review this term, check taxon scope; note FMA has specific subtypes
Added
- + mesencephalic vein editor note review this term, check taxon scope; note FMA has specific subtypes

Changes for: arthropod fat body

Deleted
- - arthropod fat body comment Editor notes: this term should be ceded to the arthropod anatomy ontology
Added
- + arthropod fat body editor note this term should be ceded to the arthropod anatomy ontology

Changes for: lesser omentum

Deleted
- - lesser omentum comment editor note: exact part of and develops from relationships need to be established
Added
- + lesser omentum editor note exact part of and develops from relationships need to be established

Changes for: pharyngotympanic tube

Deleted
- - pharyngotympanic tube comment Editor notes: we follow FMA in making this an organ, but include a separate class for the part that is epithelium, which is equivalent to the EHDAA2 structure. From this we infer the developmental relationship
Added
- + pharyngotympanic tube editor note we follow FMA in making this an organ, but include a separate class for the part that is epithelium, which is equivalent to the EHDAA2 structure. From this we infer the developmental relationship

Changes for: extraembryonic venous system

Deleted
- - extraembryonic venous system EquivalentTo venous system and part of some umbilical cord
- - extraembryonic venous system SubClassOf part of some umbilical cord
Added
- + extraembryonic venous system EquivalentTo venous system and part of some entire extraembryonic component and has part some part of some umbilical cord
- + extraembryonic venous system SubClassOf has part some part of some umbilical cord
- + extraembryonic venous system SubClassOf part of some entire extraembryonic component

Changes for: umbilical cord

Deleted
- - umbilical cord SubClassOf connects some embryo
- - umbilical cord SubClassOf connects some placenta
Added
- + umbilical cord SubClassOf connects some embryo
- + umbilical cord SubClassOf connects some placenta

Changes for: exocrine system

Added
- + exocrine system SubClassOf existence ends during some fully formed stage

Changes for: neural crest

Deleted
- - neural crest comment Editor note: consider including subclasses for pre- and post- migratory (e.g. sheets/paths/streams). Taxon notes: . Gene notes: Many factors and genes, such as Pax3 (Tremblay et al., 1995), slug (Nieto et al., 1994), AP-2 (Zhang et al., 1996; Schorle et al., 1996), and Wnt-1/3a (Ikeya et al., 1997) are expressed in the dorsal most region of the neural tube, and have been shown to be involved in the generation of neural crest cells.
Added
- + neural crest comment Gene notes: Many factors and genes, such as Pax3 (Tremblay et al., 1995), slug (Nieto et al., 1994), AP-2 (Zhang et al., 1996; Schorle et al., 1996), and Wnt-1/3a (Ikeya et al., 1997) are expressed in the dorsal most region of the neural tube, and have been shown to be involved in the generation of neural crest cells.
- + neural crest editor note consider including subclasses for pre- and post- migratory (e.g. sheets/paths/streams). Taxon notes:

Changes for: somite

Deleted
- - somite comment Editor notes: currently classified as an epithelial vesicle, consistent with EHDAA2 and UBERONREF:0000002. Consider making “somitic mesoderm” a separate term and correlate with regionalization processes. Consider moving ZFA term to ‘trunk somite’ as it is part of the trunk // When the somite becomes segmented from the segmental plate, it is composed of an epithelial sac enclosing mesenchymal somitocoel cells. Thereafter the somite differentiates into two parts, the ventro-medial mesenchymal sclerotome and the dorso-lateral epithelial dermomyotome. This change in the epithelial somite depends on surrounding tissue [PMID:15906248]
Added
- + somite comment When the somite becomes segmented from the segmental plate, it is composed of an epithelial sac enclosing mesenchymal somitocoel cells. Thereafter the somite differentiates into two parts, the ventro-medial mesenchymal sclerotome and the dorso-lateral epithelial dermomyotome. This change in the epithelial somite depends on surrounding tissue [PMID:15906248]
- + somite editor note currently classified as an epithelial vesicle, consistent with EHDAA2 and UBERONREF:0000002. Consider making ‘somitic mesoderm’ a separate term and correlate with regionalization processes. Consider moving ZFA term to ‘trunk somite’ as it is part of the trunk

Changes for: interlobar duct

Deleted
- - interlobar duct EquivalentTo duct and part of some connective tissue and connects some lobe
- - interlobar duct SubClassOf connects some lobe
Added
- + interlobar duct EquivalentTo duct and part of some connective tissue and connects some lobe
- + interlobar duct SubClassOf connects some lobe

Changes for: striated duct of salivary gland

Deleted
- - striated duct of salivary gland comment Editor note: Consider adding a generic “striated duct” class
Added
- + striated duct of salivary gland editor note Consider adding a generic ‘striated duct’ class

Changes for: extraembryonic vascular system

Deleted
- - extraembryonic vascular system EquivalentTo vascular system and part of some umbilical cord
- - extraembryonic vascular system SubClassOf mesoderm-derived structure
- - extraembryonic vascular system SubClassOf part of some umbilical cord
Added
- + extraembryonic vascular system EquivalentTo vascular system and part of some entire extraembryonic component and has part some part of some umbilical cord
- + extraembryonic vascular system SubClassOf extraembryonic structure
- + extraembryonic vascular system SubClassOf has part some part of some umbilical cord
- + extraembryonic vascular system SubClassOf part of some entire extraembryonic component

Changes for: hepatic portal system

Deleted
- - hepatic portal system SubClassOf connects some digestive tract
- - hepatic portal system SubClassOf connects some liver
Added
- + hepatic portal system SubClassOf connects some digestive tract
- + hepatic portal system SubClassOf connects some liver

Changes for: renal portal system

Deleted
- - renal portal system comment Function notes: function not well understood. Taxon notes: present in all classes of vertebrates except mammals; the mammalian kidney has a low pressure vascular network that may be its counterpart [ISBN10:0073040584]
Added
- + renal portal system comment Taxon notes: present in all classes of vertebrates except mammals; the mammalian kidney has a low pressure vascular network that may be its counterpart [ISBN10:0073040584]
- + renal portal system function notes function not well understood

Changes for: renal portal vein

Deleted
- - renal portal vein comment Function notes: function not well understood. [ISBN10:0073040584]
Added
- + renal portal vein function notes function not well understood. [ISBN10:0073040584]

Changes for: trunk region of vertebral column

Added
- + trunk region of vertebral column has exact synonym trunk vertebrae series

Changes for: metacarpal/tarsal-phalangeal joint

Deleted
- - metacarpal/tarsal-phalangeal joint EquivalentTo skeletal joint and connects some mesopodium bone and connects some proximal phalanx
- - metacarpal/tarsal-phalangeal joint SubClassOf connects some mesopodium bone
- - metacarpal/tarsal-phalangeal joint SubClassOf connects some proximal phalanx
- - metacarpal/tarsal-phalangeal joint comment Editor notes: We include these joints as being part of the digits; this is consistent with the FMA, and makes classification easier. Note that digit and metapodial regions are part-disjoint
Added
- + metacarpal/tarsal-phalangeal joint EquivalentTo skeletal joint and connects some mesopodium bone and connects some proximal phalanx
- + metacarpal/tarsal-phalangeal joint SubClassOf connects some mesopodium bone
- + metacarpal/tarsal-phalangeal joint SubClassOf connects some proximal phalanx
- + metacarpal/tarsal-phalangeal joint editor note We include these joints as being part of the digits; this is consistent with the FMA, and makes classification easier. Note that digit and metapodial regions are part-disjoint

Changes for: intraembryonic coelom

Deleted
- - intraembryonic coelom comment Editor notes: consider merging with coelom. TODO - add spatial relationships to halves of LPM. Note the OG places XAO and ZFA coelem terms here. Todo: check ZFA, which appears to be a structure present in adults
Added
- + intraembryonic coelom editor note consider merging with coelom. TODO - add spatial relationships to halves of LPM. Note the OG places XAO and ZFA coelem terms here. Todo: check ZFA, which appears to be a structure present in adults

Changes for: rete ovarii

Deleted
- - rete ovarii comment Editor note: todo
Added
- + rete ovarii editor note todo

Changes for: fallopian tube

Deleted
- - fallopian tube SubClassOf connects some female gonad
- - fallopian tube SubClassOf connects some uterus
Added
- + fallopian tube SubClassOf connects some female gonad
- + fallopian tube SubClassOf connects some uterus

Changes for: parasphenoid-pterosphenoid joint

Deleted
- - parasphenoid-pterosphenoid joint EquivalentTo skeletal joint and connects some parasphenoid and connects some pterosphenoid
- - parasphenoid-pterosphenoid joint SubClassOf connects some parasphenoid
- - parasphenoid-pterosphenoid joint SubClassOf connects some pterosphenoid
Added
- + parasphenoid-pterosphenoid joint EquivalentTo skeletal joint and connects some parasphenoid and connects some pterosphenoid
- + parasphenoid-pterosphenoid joint SubClassOf connects some parasphenoid
- + parasphenoid-pterosphenoid joint SubClassOf connects some pterosphenoid

Changes for: sphenozygomatic suture

Deleted
- - sphenozygomatic suture EquivalentTo cranial suture and connects some sphenoid bone and connects some jugal bone
- - sphenozygomatic suture SubClassOf connects some jugal bone
- - sphenozygomatic suture SubClassOf connects some sphenoid bone
Added
- + sphenozygomatic suture EquivalentTo cranial suture and connects some sphenoid bone and connects some jugal bone
- + sphenozygomatic suture SubClassOf connects some jugal bone
- + sphenozygomatic suture SubClassOf connects some sphenoid bone

Changes for: occipitomastoid suture

Deleted
- - occipitomastoid suture SubClassOf connects some occipital bone
- - occipitomastoid suture SubClassOf connects some temporal bone
Added
- + occipitomastoid suture SubClassOf connects some occipital bone
- + occipitomastoid suture SubClassOf connects some temporal bone

Changes for: skin mucus

Deleted
- - skin mucus SubClassOf bodily secretion
- - skin mucus SubClassOf develops from some mucous gland
- - skin mucus comment Editor notes: Consider making a specific class e.g. mucus coating to represent the entire coating rather than an portion of secretion of a mucus gland in the skin. Candidate definition - “The epidermal mucus of fish regulates swimming speed by controlling the hydrodynamic resistance of the skin surface. The mucus is also presumed to serve as a defence against pathogenic organisms and is intimately associated with osmoregulation.” [BTO:0005082]
- - skin mucus database cross reference BTO:0005082
Added
- + skin mucus EquivalentTo mucus and produced by some skin mucous gland
- + skin mucus SubClassOf mucus
- + skin mucus SubClassOf produced by some skin mucous gland
- + skin mucus definition A mucous secretion that is produced by glands in the epidermis. { database cross reference=UBERON:cjm }
- + skin mucus has related synonym skin mucous

Changes for: parietomastoid suture

Deleted
- - parietomastoid suture SubClassOf connects some temporal bone
- - parietomastoid suture SubClassOf connects some tetrapod parietal bone
Added
- + parietomastoid suture SubClassOf connects some temporal bone
- + parietomastoid suture SubClassOf connects some tetrapod parietal bone

Changes for: sphenoparietal suture

Deleted
- - sphenoparietal suture EquivalentTo cranial suture and connects some tetrapod parietal bone and connects some sphenoid bone
- - sphenoparietal suture SubClassOf connects some sphenoid bone
- - sphenoparietal suture SubClassOf connects some tetrapod parietal bone
Added
- + sphenoparietal suture EquivalentTo cranial suture and connects some tetrapod parietal bone and connects some sphenoid bone
- + sphenoparietal suture SubClassOf connects some sphenoid bone
- + sphenoparietal suture SubClassOf connects some tetrapod parietal bone

Changes for: sphenofrontal suture

Deleted
- - sphenofrontal suture EquivalentTo cranial suture and connects some tetrapod frontal bone and connects some sphenoid bone
- - sphenofrontal suture SubClassOf connects some sphenoid bone
- - sphenofrontal suture SubClassOf connects some tetrapod frontal bone
Added
- + sphenofrontal suture EquivalentTo cranial suture and connects some tetrapod frontal bone and connects some sphenoid bone
- + sphenofrontal suture SubClassOf connects some sphenoid bone
- + sphenofrontal suture SubClassOf connects some tetrapod frontal bone

Changes for: intertrochanteric crest

Deleted
- - intertrochanteric crest SubClassOf connects some greater trochanter
- - intertrochanteric crest SubClassOf connects some lesser trochanter
Added
- + intertrochanteric crest SubClassOf connects some greater trochanter
- + intertrochanteric crest SubClassOf connects some lesser trochanter

Changes for: premaxillary-maxillary joint

Deleted
- - premaxillary-maxillary joint EquivalentTo skeletal joint and connects some premaxilla and connects some maxilla
- - premaxillary-maxillary joint SubClassOf connects some maxilla
- - premaxillary-maxillary joint SubClassOf connects some premaxilla
Added
- + premaxillary-maxillary joint EquivalentTo skeletal joint and connects some premaxilla and connects some maxilla
- + premaxillary-maxillary joint SubClassOf connects some maxilla
- + premaxillary-maxillary joint SubClassOf connects some premaxilla

Changes for: odontogenic mesenchyme

Deleted
- - odontogenic mesenchyme comment Editor notes: we follow ZFA in introducing an additional distinction between the dental papilla and the (uncondensed) mesenchyme. Note that in some species such as zebrafish teeth are not part of the mouth, and sharks have dermal denticles which share similar developmental origins with teeth. For now we assume a NC origin for all and add a taxon restriction to 1st arch mesenchyme
Added
- + odontogenic mesenchyme editor note we follow ZFA in introducing an additional distinction between the dental papilla and the (uncondensed) mesenchyme. Note that in some species such as zebrafish teeth are not part of the mouth, and sharks have dermal denticles which share similar developmental origins with teeth. For now we assume a NC origin for all and add a taxon restriction to 1st arch mesenchyme

Changes for: dental epithelium

Deleted
- - dental epithelium comment Editor notes: see comments for dentail organ. Development notes: In the developing molar dentition of the mouse, tooth inductive po- tential resides in the dental epithelium until embryonic day (E)12.5 (3). Thereafter, tooth inductive potential shifts to neural crest-derived dental mesenchyme, which acquires the ability to direct tooth formation in nonodontogenic tissues (3, 4)[PMID:10954731]. Editor notes: todo - full developmental relationships
Added
- + dental epithelium comment . Editor notes: todo - full developmental relationships
- + dental epithelium editor note see comments for dentail organ. Development notes: In the developing molar dentition of the mouse, tooth inductive po- tential resides in the dental epithelium until embryonic day (E)12.5 (3). Thereafter, tooth inductive potential shifts to neural crest-derived dental mesenchyme, which acquires the ability to direct tooth formation in nonodontogenic tissues (3, 4)[PMID:10954731]

Changes for: upper primary molar tooth

Added
- + upper primary molar tooth has exact synonym upper deciduous molar

Changes for: frontal-pterotic joint

Deleted
- - frontal-pterotic joint EquivalentTo skeletal joint and connects some actinopterygian frontal bone and connects some pterotic
- - frontal-pterotic joint SubClassOf connects some actinopterygian frontal bone
- - frontal-pterotic joint SubClassOf connects some pterotic
Added
- + frontal-pterotic joint EquivalentTo skeletal joint and connects some actinopterygian frontal bone and connects some pterotic
- + frontal-pterotic joint SubClassOf connects some actinopterygian frontal bone
- + frontal-pterotic joint SubClassOf connects some pterotic

Changes for: opercle-interopercle joint

Deleted
- - opercle-interopercle joint EquivalentTo skeletal joint and connects some opercle and connects some interopercle
- - opercle-interopercle joint SubClassOf connects some interopercle
- - opercle-interopercle joint SubClassOf connects some opercle
Added
- + opercle-interopercle joint EquivalentTo skeletal joint and connects some opercle and connects some interopercle
- + opercle-interopercle joint SubClassOf connects some interopercle
- + opercle-interopercle joint SubClassOf connects some opercle

Changes for: crop

Deleted
- - crop comment Editor notes: we follow WP and place as part of the esophagus. Taxon notes: Aves specific structure - consider adding functional grouping class. Kardong: some cetaceans have a crop-like structure
Added
- + crop comment Taxon notes: Aves specific structure - consider adding functional grouping class. Kardong: some cetaceans have a crop-like structure
- + crop editor note we follow WP and place as part of the esophagus

Changes for: ruminant stomach

Deleted
- - ruminant stomach comment Editor notes: Consider classifying each subdivision as ‘stomach chamber’
Added
- + ruminant stomach editor note Consider classifying each subdivision as ‘stomach chamber’

Changes for: roof of mouth

Deleted
- - roof of mouth comment Editor notes: check subclasses to verify if they refer to a multi-tissue structure or a subdivision of the skeleton
Added
- + roof of mouth editor note check subclasses to verify if they refer to a multi-tissue structure or a subdivision of the skeleton

Changes for: intertarsal joint

Deleted
- - intertarsal joint EquivalentTo skeletal joint and ObjectMinCardinality( connects tarsal bone ) and ObjectMaxCardinality( connects tarsal bone )
- - intertarsal joint SubClassOf connects some tarsal bone
Added
- + intertarsal joint EquivalentTo skeletal joint and ObjectMinCardinality( connects tarsal bone ) and ObjectMaxCardinality( connects tarsal bone )
- + intertarsal joint SubClassOf connects some tarsal bone

Changes for: incus pre-cartilage condensation

Deleted
- - incus pre-cartilage condensation comment Editor notes: in EHDAA2 this develops from both mandibular and maxillary mesenchyme. We have still to extend homology relationships from quadrate/incus to their ontogenic precursors (
Added
- + incus pre-cartilage condensation editor note in EHDAA2 this develops from both mandibular and maxillary mesenchyme. We have still to extend homology relationships from quadrate/incus to their ontogenic precursors (

Changes for: facial bone primordium

Deleted
- - facial bone primordium comment Editor notes: check this for developmental relationships
Added
- + facial bone primordium editor note check this for developmental relationships

Changes for: mural trophectoderm

Deleted
- - mural trophectoderm SubClassOf extraembryonic structure
Added
- + mural trophectoderm SubClassOf part of some entire extraembryonic component
- + mural trophectoderm SubClassOf transitional anatomical structure

Changes for: infundibular recess of 3rd ventricle

Deleted
- - infundibular recess of 3rd ventricle comment Editor note: in FMA this is a cavity, whereas in EHDAA2 it is an epithelial sac
Added
- + infundibular recess of 3rd ventricle editor note in FMA this is a cavity, whereas in EHDAA2 it is an epithelial sac

Changes for: laryngotracheal groove

Deleted
- - laryngotracheal groove comment Editor notes: Note we currently have pharynx as part of the upper respiratory tract - separate by development?
Added
- + laryngotracheal groove editor note Note we currently have pharynx as part of the upper respiratory tract - separate by development?

Changes for: pyramid of medulla oblongata

Deleted
- - pyramid of medulla oblongata has exact synonym medullary pyramid { database cross reference=FMA:75254 }
- - pyramid of medulla oblongata has exact synonym pyramid of medulla { database cross reference=FMA:75254 }
Added
- + pyramid of medulla oblongata database cross reference http://www.snomedbrowser.com/Codes/Details/279289009
- + pyramid of medulla oblongata has broad synonym medullary pyramid { database cross reference=FMA:75254 }
- + pyramid of medulla oblongata has broad synonym pyramid of medulla { database cross reference=FMA:75254 }

Changes for: pleuroperitoneal canal

Deleted
- - pleuroperitoneal canal EquivalentTo epithelial tube and connects some peritoneal cavity and connects some pleural cavity
- - pleuroperitoneal canal SubClassOf connects some peritoneal cavity
- - pleuroperitoneal canal SubClassOf connects some pleural cavity
Added
- + pleuroperitoneal canal EquivalentTo epithelial tube and connects some peritoneal cavity and connects some pleural cavity
- + pleuroperitoneal canal SubClassOf connects some peritoneal cavity
- + pleuroperitoneal canal SubClassOf connects some pleural cavity

Changes for: polar trophectoderm

Deleted
- - polar trophectoderm SubClassOf extraembryonic structure
Added
- + polar trophectoderm SubClassOf part of some entire extraembryonic component
- + polar trophectoderm SubClassOf transitional anatomical structure

Changes for: orbitosphenoid-prootic joint

Deleted
- - orbitosphenoid-prootic joint EquivalentTo skeletal joint and connects some orbitosphenoid and connects some prootic bone
- - orbitosphenoid-prootic joint SubClassOf connects some orbitosphenoid
- - orbitosphenoid-prootic joint SubClassOf connects some prootic bone
Added
- + orbitosphenoid-prootic joint EquivalentTo skeletal joint and connects some orbitosphenoid and connects some prootic bone
- + orbitosphenoid-prootic joint SubClassOf connects some orbitosphenoid
- + orbitosphenoid-prootic joint SubClassOf connects some prootic bone

Changes for: tooth enamel organ

Deleted
- - tooth enamel organ comment Editor notes: some sources treat the dental organ as epithelium - we treat it as the mereological sum of dentail epithelium plus dental papilla (consistent with treatment in many AOs), but this may be revised.Development notes: NOT develeops_from NC[UBERONREF:0000002]. Alternate definitioon: A cellular aggregation seen in histologic sections of a developing tooth. It lies above a condensation of ectomesenchymal cells called the odontogenic papilla. Historically, enamel organ has been the term to describe this structure, but it was attempted unsuccessfully in recent years to change the name to dental organ in order to better represent its multiple functions apart from enamel formation[WP]
Added
- + tooth enamel organ editor note some sources treat the dental organ as epithelium - we treat it as the mereological sum of dentail epithelium plus dental papilla (consistent with treatment in many AOs), but this may be revised.Development notes: NOT develeops_from NC[UBERONREF:0000002]. Alternate definitioon: A cellular aggregation seen in histologic sections of a developing tooth. It lies above a condensation of ectomesenchymal cells called the odontogenic papilla. Historically, enamel organ has been the term to describe this structure, but it was attempted unsuccessfully in recent years to change the name to dental organ in order to better represent its multiple functions apart from enamel formation[WP]

Changes for: autopalatine-vomer joint

Deleted
- - autopalatine-vomer joint EquivalentTo skeletal joint and connects some vomer and connects some autopalatine
- - autopalatine-vomer joint SubClassOf connects some autopalatine
- - autopalatine-vomer joint SubClassOf connects some vomer
Added
- + autopalatine-vomer joint EquivalentTo skeletal joint and connects some vomer and connects some autopalatine
- + autopalatine-vomer joint SubClassOf connects some autopalatine
- + autopalatine-vomer joint SubClassOf connects some vomer

Changes for: dentary-anguloarticular joint

Deleted
- - dentary-anguloarticular joint EquivalentTo skeletal joint and connects some dentary and connects some articular/anguloarticular
- - dentary-anguloarticular joint SubClassOf connects some articular/anguloarticular
- - dentary-anguloarticular joint SubClassOf connects some dentary
Added
- + dentary-anguloarticular joint EquivalentTo skeletal joint and connects some dentary and connects some articular/anguloarticular
- + dentary-anguloarticular joint SubClassOf connects some articular/anguloarticular
- + dentary-anguloarticular joint SubClassOf connects some dentary

Changes for: neonate stage

Deleted
- - neonate stage comment Editor note: consider splitting infant/newborn
Added
- + neonate stage editor note consider splitting infant/newborn

Changes for: parasphenoid-basioccipital joint

Deleted
- - parasphenoid-basioccipital joint EquivalentTo skeletal joint and connects some basioccipital bone and connects some parasphenoid
- - parasphenoid-basioccipital joint SubClassOf connects some basioccipital bone
- - parasphenoid-basioccipital joint SubClassOf connects some parasphenoid
Added
- + parasphenoid-basioccipital joint EquivalentTo skeletal joint and connects some basioccipital bone and connects some parasphenoid
- + parasphenoid-basioccipital joint SubClassOf connects some basioccipital bone
- + parasphenoid-basioccipital joint SubClassOf connects some parasphenoid

Changes for: pterosphenoid-orbitosphenoid joint

Deleted
- - pterosphenoid-orbitosphenoid joint EquivalentTo skeletal joint and connects some orbitosphenoid and connects some pterosphenoid
- - pterosphenoid-orbitosphenoid joint SubClassOf connects some orbitosphenoid
- - pterosphenoid-orbitosphenoid joint SubClassOf connects some pterosphenoid
Added
- + pterosphenoid-orbitosphenoid joint EquivalentTo skeletal joint and connects some orbitosphenoid and connects some pterosphenoid
- + pterosphenoid-orbitosphenoid joint SubClassOf connects some orbitosphenoid
- + pterosphenoid-orbitosphenoid joint SubClassOf connects some pterosphenoid

Changes for: ceratohyal-dorsal hypohyal joint

Deleted
- - ceratohyal-dorsal hypohyal joint EquivalentTo skeletal joint and connects some ceratohyal bone and connects some dorsal hypohyal bone
- - ceratohyal-dorsal hypohyal joint SubClassOf connects some ceratohyal bone
- - ceratohyal-dorsal hypohyal joint SubClassOf connects some dorsal hypohyal bone
Added
- + ceratohyal-dorsal hypohyal joint EquivalentTo skeletal joint and connects some ceratohyal bone and connects some dorsal hypohyal bone
- + ceratohyal-dorsal hypohyal joint SubClassOf connects some ceratohyal bone
- + ceratohyal-dorsal hypohyal joint SubClassOf connects some dorsal hypohyal bone

Changes for: epihyal-ceratohyal joint

Deleted
- - epihyal-ceratohyal joint EquivalentTo skeletal joint and connects some ceratohyal bone and connects some posterior ceratohyal
- - epihyal-ceratohyal joint SubClassOf connects some ceratohyal bone
- - epihyal-ceratohyal joint SubClassOf connects some posterior ceratohyal
Added
- + epihyal-ceratohyal joint EquivalentTo skeletal joint and connects some ceratohyal bone and connects some posterior ceratohyal
- + epihyal-ceratohyal joint SubClassOf connects some ceratohyal bone
- + epihyal-ceratohyal joint SubClassOf connects some posterior ceratohyal

Changes for: dorsal hypohyal-ventral hypohyal joint

Deleted
- - dorsal hypohyal-ventral hypohyal joint EquivalentTo skeletal joint and connects some dorsal hypohyal bone and connects some ventral hypohyal bone
- - dorsal hypohyal-ventral hypohyal joint SubClassOf connects some dorsal hypohyal bone
- - dorsal hypohyal-ventral hypohyal joint SubClassOf connects some ventral hypohyal bone
Added
- + dorsal hypohyal-ventral hypohyal joint EquivalentTo skeletal joint and connects some dorsal hypohyal bone and connects some ventral hypohyal bone
- + dorsal hypohyal-ventral hypohyal joint SubClassOf connects some dorsal hypohyal bone
- + dorsal hypohyal-ventral hypohyal joint SubClassOf connects some ventral hypohyal bone

Changes for: ceratohyal-ventral hypohyal joint

Deleted
- - ceratohyal-ventral hypohyal joint EquivalentTo skeletal joint and connects some ceratohyal bone and connects some ventral hypohyal bone
- - ceratohyal-ventral hypohyal joint SubClassOf connects some ceratohyal bone
- - ceratohyal-ventral hypohyal joint SubClassOf connects some ventral hypohyal bone
Added
- + ceratohyal-ventral hypohyal joint EquivalentTo skeletal joint and connects some ceratohyal bone and connects some ventral hypohyal bone
- + ceratohyal-ventral hypohyal joint SubClassOf connects some ceratohyal bone
- + ceratohyal-ventral hypohyal joint SubClassOf connects some ventral hypohyal bone

Changes for: dorsal hypohyal-urohyal joint

Deleted
- - dorsal hypohyal-urohyal joint EquivalentTo skeletal joint and connects some ceratohyal cartilage and connects some dorsal hypohyal bone and connects some urohyal
- - dorsal hypohyal-urohyal joint SubClassOf connects some ceratohyal cartilage
- - dorsal hypohyal-urohyal joint SubClassOf connects some dorsal hypohyal bone
- - dorsal hypohyal-urohyal joint SubClassOf connects some urohyal
Added
- + dorsal hypohyal-urohyal joint EquivalentTo skeletal joint and connects some ceratohyal cartilage and connects some dorsal hypohyal bone and connects some urohyal
- + dorsal hypohyal-urohyal joint SubClassOf connects some ceratohyal cartilage
- + dorsal hypohyal-urohyal joint SubClassOf connects some dorsal hypohyal bone
- + dorsal hypohyal-urohyal joint SubClassOf connects some urohyal

Changes for: inter-ventral hypohyal joint

Deleted
- - inter-ventral hypohyal joint EquivalentTo skeletal joint and connects some ceratohyal cartilage and connects some ventral hypohyal bone
- - inter-ventral hypohyal joint SubClassOf connects some ceratohyal cartilage
- - inter-ventral hypohyal joint SubClassOf connects some ventral hypohyal bone
Added
- + inter-ventral hypohyal joint EquivalentTo skeletal joint and connects some ceratohyal cartilage and connects some ventral hypohyal bone
- + inter-ventral hypohyal joint SubClassOf connects some ceratohyal cartilage
- + inter-ventral hypohyal joint SubClassOf connects some ventral hypohyal bone

Changes for: ventral hypohyal-urohyal joint

Deleted
- - ventral hypohyal-urohyal joint EquivalentTo skeletal joint and connects some ventral hypohyal bone and connects some urohyal
- - ventral hypohyal-urohyal joint SubClassOf connects some urohyal
- - ventral hypohyal-urohyal joint SubClassOf connects some ventral hypohyal bone
Added
- + ventral hypohyal-urohyal joint EquivalentTo skeletal joint and connects some ventral hypohyal bone and connects some urohyal
- + ventral hypohyal-urohyal joint SubClassOf connects some urohyal
- + ventral hypohyal-urohyal joint SubClassOf connects some ventral hypohyal bone

Changes for: quadrate-hyomandibula joint

Deleted
- - quadrate-hyomandibula joint EquivalentTo skeletal joint and connects some quadrate bone and connects some hyomandibular bone
- - quadrate-hyomandibula joint SubClassOf connects some hyomandibular bone
- - quadrate-hyomandibula joint SubClassOf connects some quadrate bone
Added
- + quadrate-hyomandibula joint EquivalentTo skeletal joint and connects some quadrate bone and connects some hyomandibular bone
- + quadrate-hyomandibula joint SubClassOf connects some hyomandibular bone
- + quadrate-hyomandibula joint SubClassOf connects some quadrate bone

Changes for: quadrate-metapterygoid joint

Deleted
- - quadrate-metapterygoid joint EquivalentTo skeletal joint and connects some quadrate bone and connects some metapterygoid
- - quadrate-metapterygoid joint SubClassOf connects some metapterygoid
- - quadrate-metapterygoid joint SubClassOf connects some quadrate bone
Added
- + quadrate-metapterygoid joint EquivalentTo skeletal joint and connects some quadrate bone and connects some metapterygoid
- + quadrate-metapterygoid joint SubClassOf connects some metapterygoid
- + quadrate-metapterygoid joint SubClassOf connects some quadrate bone

Changes for: presumptive neural plate

Deleted
- - presumptive neural plate comment Editor notes: consider merging
Added
- + presumptive neural plate editor note consider merging

Changes for: intervertebral disk of sixth cervical vertebra

Deleted
- - intervertebral disk of sixth cervical vertebra EquivalentTo intervertebral disk and connects some mammalian cervical vertebra 6 and connects some mammalian cervical vertebra 7
- - intervertebral disk of sixth cervical vertebra SubClassOf connects some mammalian cervical vertebra 6
- - intervertebral disk of sixth cervical vertebra SubClassOf connects some mammalian cervical vertebra 7
Added
- + intervertebral disk of sixth cervical vertebra EquivalentTo intervertebral disk and connects some mammalian cervical vertebra 6 and connects some mammalian cervical vertebra 7
- + intervertebral disk of sixth cervical vertebra SubClassOf connects some mammalian cervical vertebra 6
- + intervertebral disk of sixth cervical vertebra SubClassOf connects some mammalian cervical vertebra 7

Changes for: intervertebral disk of fifth cervical vertebra

Deleted
- - intervertebral disk of fifth cervical vertebra EquivalentTo intervertebral disk and connects some mammalian cervical vertebra 5 and connects some mammalian cervical vertebra 6
- - intervertebral disk of fifth cervical vertebra SubClassOf connects some mammalian cervical vertebra 5
- - intervertebral disk of fifth cervical vertebra SubClassOf connects some mammalian cervical vertebra 6
Added
- + intervertebral disk of fifth cervical vertebra EquivalentTo intervertebral disk and connects some mammalian cervical vertebra 5 and connects some mammalian cervical vertebra 6
- + intervertebral disk of fifth cervical vertebra SubClassOf connects some mammalian cervical vertebra 5
- + intervertebral disk of fifth cervical vertebra SubClassOf connects some mammalian cervical vertebra 6

Changes for: intervertebral disk of fourth cervical vertebra

Deleted
- - intervertebral disk of fourth cervical vertebra EquivalentTo intervertebral disk and connects some mammalian cervical vertebra 4 and connects some mammalian cervical vertebra 5
- - intervertebral disk of fourth cervical vertebra SubClassOf connects some mammalian cervical vertebra 4
- - intervertebral disk of fourth cervical vertebra SubClassOf connects some mammalian cervical vertebra 5
Added
- + intervertebral disk of fourth cervical vertebra EquivalentTo intervertebral disk and connects some mammalian cervical vertebra 4 and connects some mammalian cervical vertebra 5
- + intervertebral disk of fourth cervical vertebra SubClassOf connects some mammalian cervical vertebra 4
- + intervertebral disk of fourth cervical vertebra SubClassOf connects some mammalian cervical vertebra 5

Changes for: intervertebral disk of third cervical vertebra

Deleted
- - intervertebral disk of third cervical vertebra EquivalentTo intervertebral disk and connects some mammalian cervical vertebra 3 and connects some mammalian cervical vertebra 4
- - intervertebral disk of third cervical vertebra SubClassOf connects some mammalian cervical vertebra 3
- - intervertebral disk of third cervical vertebra SubClassOf connects some mammalian cervical vertebra 4
Added
- + intervertebral disk of third cervical vertebra EquivalentTo intervertebral disk and connects some mammalian cervical vertebra 3 and connects some mammalian cervical vertebra 4
- + intervertebral disk of third cervical vertebra SubClassOf connects some mammalian cervical vertebra 3
- + intervertebral disk of third cervical vertebra SubClassOf connects some mammalian cervical vertebra 4

Changes for: intervertebral disk of atlas

Deleted
- - intervertebral disk of atlas EquivalentTo intervertebral disk and connects some vertebral bone 1 and connects some vertebral bone 2
- - intervertebral disk of atlas SubClassOf connects some vertebral bone 1
- - intervertebral disk of atlas SubClassOf connects some vertebral bone 2
Added
- + intervertebral disk of atlas EquivalentTo intervertebral disk and connects some vertebral bone 1 and connects some vertebral bone 2
- + intervertebral disk of atlas SubClassOf connects some vertebral bone 1
- + intervertebral disk of atlas SubClassOf connects some vertebral bone 2

Changes for: intervertebral disk of axis

Deleted
- - intervertebral disk of axis EquivalentTo intervertebral disk and connects some vertebral bone 2 and connects some mammalian cervical vertebra 3
- - intervertebral disk of axis SubClassOf connects some mammalian cervical vertebra 3
- - intervertebral disk of axis SubClassOf connects some vertebral bone 2
Added
- + intervertebral disk of axis EquivalentTo intervertebral disk and connects some vertebral bone 2 and connects some mammalian cervical vertebra 3
- + intervertebral disk of axis SubClassOf connects some mammalian cervical vertebra 3
- + intervertebral disk of axis SubClassOf connects some vertebral bone 2

Changes for: intervertebral disk of seventh cervical vertebra

Deleted
- - intervertebral disk of seventh cervical vertebra EquivalentTo intervertebral disk and connects some thoracic vertebra and connects some mammalian cervical vertebra 7
- - intervertebral disk of seventh cervical vertebra SubClassOf connects some mammalian cervical vertebra 7
- - intervertebral disk of seventh cervical vertebra SubClassOf connects some thoracic vertebra
Added
- + intervertebral disk of seventh cervical vertebra EquivalentTo intervertebral disk and connects some thoracic vertebra and connects some mammalian cervical vertebra 7
- + intervertebral disk of seventh cervical vertebra SubClassOf connects some mammalian cervical vertebra 7
- + intervertebral disk of seventh cervical vertebra SubClassOf connects some thoracic vertebra

Changes for: kidney rudiment

Deleted
- - kidney rudiment comment Editor notes: class added for consistency with GO - consider merging with kidney mesenchyme.
Added
- + kidney rudiment editor note class added for consistency with GO - consider merging with kidney mesenchyme.

Changes for: muscle structure

Added
- + muscle structure database cross reference FMA:30316

Changes for: neuropore

Deleted
- - neuropore SubClassOf connects some neural tube lumen
Added
- + neuropore SubClassOf connects some neural tube lumen

Changes for: anterior visceral endoderm

Deleted
- - anterior visceral endoderm SubClassOf develops from some endoderm
- - anterior visceral endoderm SubClassOf endoderm-derived structure
- - anterior visceral endoderm SubClassOf extraembryonic structure
Added
- + anterior visceral endoderm SubClassOf visceral endoderm

Changes for: chorionic plate

Deleted
- - chorionic plate SubClassOf tissue
Added
- + chorionic plate SubClassOf extraembryonic tissue

Changes for: spongiotrophoblast layer

Added
- + spongiotrophoblast layer SubClassOf extraembryonic tissue

Changes for: mucosa of sphenoidal sinus

Deleted
- - mucosa of sphenoidal sinus comment Editor note: decide whether cavities can be part of mucosae
Added
- + mucosa of sphenoidal sinus editor note decide whether cavities can be part of mucosae

Changes for: cerebellum vermis lobule I

Added
- + cerebellum vermis lobule I database cross reference http://www.snomedbrowser.com/Codes/Details/279380005

Changes for: epibranchial 3-pharyngobranchial 3 joint

Deleted
- - epibranchial 3-pharyngobranchial 3 joint EquivalentTo skeletal joint and connects some epibranchial 3 bone and connects some pharyngobranchial 3 bone and connects some epibranchial 3 cartilage and connects some pharyngobranchial 3 cartilage
- - epibranchial 3-pharyngobranchial 3 joint SubClassOf connects some epibranchial 3 bone
- - epibranchial 3-pharyngobranchial 3 joint SubClassOf connects some epibranchial 3 cartilage
- - epibranchial 3-pharyngobranchial 3 joint SubClassOf connects some pharyngobranchial 3 bone
- - epibranchial 3-pharyngobranchial 3 joint SubClassOf connects some pharyngobranchial 3 cartilage
Added
- + epibranchial 3-pharyngobranchial 3 joint EquivalentTo skeletal joint and connects some epibranchial 3 bone and connects some pharyngobranchial 3 bone and connects some epibranchial 3 cartilage and connects some pharyngobranchial 3 cartilage
- + epibranchial 3-pharyngobranchial 3 joint SubClassOf connects some epibranchial 3 bone
- + epibranchial 3-pharyngobranchial 3 joint SubClassOf connects some epibranchial 3 cartilage
- + epibranchial 3-pharyngobranchial 3 joint SubClassOf connects some pharyngobranchial 3 bone
- + epibranchial 3-pharyngobranchial 3 joint SubClassOf connects some pharyngobranchial 3 cartilage

Changes for: internal male genitalia

Deleted
- - internal male genitalia comment Editor note: consider splitting genitalia from genital organ
Added
- + internal male genitalia editor note consider splitting genitalia from genital organ

Changes for: hairline

Deleted
- - hairline EquivalentTo anatomical line and connects some scalp and connects some forehead
- - hairline SubClassOf connects some forehead
- - hairline SubClassOf connects some scalp
Added
- + hairline EquivalentTo anatomical line and connects some scalp and connects some forehead
- + hairline SubClassOf connects some forehead
- + hairline SubClassOf connects some scalp

Changes for: anatomical conduit

Added
- + anatomical conduit has related synonym opening

Changes for: genitourinary system

Added
- + genitourinary system SubClassOf existence ends during some fully formed stage

Changes for: chorionic villus

Added
- + chorionic villus SubClassOf extraembryonic structure

Changes for: pharyngeal pouch 4

Deleted
- - pharyngeal pouch 4 comment Development notes: Derivatives include: superior parathyroid glands and ultimobranchial body which forms the parafollicular C-Cells of the thyroid gland. Musculature and cartilage of larynx (along with the sixth pharyngeal pouch)[WP]
- - pharyngeal pouch 4 definition A pharyngeal pouch between pharyngeal arches 4 and 5 { database cross reference=Fourth pouch , database cross reference=http://www.ncbi.nlm.nih.gov/pubmed/16313389 , database cross reference=ISBN10:0124020607 }
Added
- + pharyngeal pouch 4 comment Development notes: Derivatives include: superior parathyroid glands and ultimobranchial body which forms the parafollicular C-Cells of the thyroid gland. Musculature and cartilage of larynx (along with the sixth pharyngeal pouch)[WP] in most mammals, excluding rodents, the dorsal part of each fourth pouch develops into a superior parathyroid gland (parathyroid IV), which lies on the dorsal surface of the thyroid gland (the parathyroid glands derived from the third pouches descend with the thymus and are carried to a more inferior position than the parathyroid glands that are derived from the fourth pouches); the elongated ventral part of each fourth pouch develops into the ultimopharyngeal body, which fuses with the thyroid gland, giving rise to the calcitonin-producing parafollicular or C-cells of the thyroid gland. In the mouse, but also in the rat and hamster, the dorsal fourth pouch does not generate a parathyroid. Thus, rodents develop only one pair of parathyroid glands.[MP]
- + pharyngeal pouch 4 definition A pharyngeal pouch between pharyngeal arch 4 and arch 5 or 6 (a fifth arch never establishes in amniotes). { database cross reference=Fourth pouch , database cross reference=http://www.ncbi.nlm.nih.gov/pubmed/16313389 , database cross reference=ISBN10:0124020607 }
- + pharyngeal pouch 4 has exact synonym fourth branchial pouch

Changes for: labyrinthine layer blood vessel

Added
- + labyrinthine layer blood vessel SubClassOf extraembryonic structure

Changes for: hemopoietic organ

Deleted
- - hemopoietic organ comment Editor notes: consider splitting out lymph organ. AO notes: the FMA class ‘lymphoid organ’ is a general anatomical term
Added
- + hemopoietic organ comment AO notes: the FMA class ‘lymphoid organ’ is a general anatomical term
- + hemopoietic organ editor note consider splitting out lymph organ

Changes for: blood vessel smooth muscle

Deleted
- - blood vessel smooth muscle comment Function notes: Vascular smooth muscle contracts or relaxes to both change the volume of blood vessels and the local blood pressure, a mechanism that is responsible for the redistribution of the blood within the body to areas where it is needed (i.e. areas with temporarily enhanced oxygen consumption). Thus the main function of vascular smooth muscle tonus is to regulate the caliber of the blood vessels in the body. Excessive vasoconstriction leads to hypertension, while excessive vasodilation as in shock leads to hypotension.
Added
- + blood vessel smooth muscle function notes Vascular smooth muscle contracts or relaxes to both change the volume of blood vessels and the local blood pressure, a mechanism that is responsible for the redistribution of the blood within the body to areas where it is needed (i.e. areas with temporarily enhanced oxygen consumption). Thus the main function of vascular smooth muscle tonus is to regulate the caliber of the blood vessels in the body. Excessive vasoconstriction leads to hypertension, while excessive vasodilation as in shock leads to hypotension.

Changes for: iris smooth muscle

Deleted
- - iris smooth muscle comment Editor notes: see notes for muscle of iris.
Added
- + iris smooth muscle editor note see notes for muscle of iris.

Changes for: renal vesicle

Deleted
- - renal vesicle comment Editor notes: note that this class includes both metanephric and mesonephric vesicles - ZFA and EHDAA2 associations are placed with these classes. TODO - make a more specific develops_from relationship - see UBERON:0005107
Added
- + renal vesicle editor note note that this class includes both metanephric and mesonephric vesicles - ZFA and EHDAA2 associations are placed with these classes. TODO - make a more specific develops_from relationship - see UBERON:0005107 ! metanephric cap

Changes for: autopalatine-lateral ethmoid joint

Deleted
- - autopalatine-lateral ethmoid joint EquivalentTo skeletal joint and connects some lateral ethmoid bone and connects some autopalatine
- - autopalatine-lateral ethmoid joint SubClassOf connects some autopalatine
- - autopalatine-lateral ethmoid joint SubClassOf connects some lateral ethmoid bone
Added
- + autopalatine-lateral ethmoid joint EquivalentTo skeletal joint and connects some lateral ethmoid bone and connects some autopalatine
- + autopalatine-lateral ethmoid joint SubClassOf connects some autopalatine
- + autopalatine-lateral ethmoid joint SubClassOf connects some lateral ethmoid bone

Changes for: atrioventricular canal

Deleted
- - atrioventricular canal SubClassOf connects some cardiac atrium
- - atrioventricular canal SubClassOf connects some cardiac ventricle
Added
- + atrioventricular canal SubClassOf connects some cardiac atrium
- + atrioventricular canal SubClassOf connects some cardiac ventricle

Changes for: sinoatrial valve

Deleted
- - sinoatrial valve SubClassOf connects some cardiac atrium
- - sinoatrial valve SubClassOf connects some sinus venosus
Added
- + sinoatrial valve SubClassOf connects some cardiac atrium
- + sinoatrial valve SubClassOf connects some sinus venosus

Changes for: ductus venosus

Deleted
- - ductus venosus comment Editor notes: add class for fetal shunt?
Added
- + ductus venosus editor note add class for fetal shunt?

Changes for: ureteric bud tip

Deleted
- - ureteric bud tip comment Editor note: MA placement to be checked
Added
- + ureteric bud tip editor note MA placement to be checked

Changes for: communicating artery

Deleted
- - communicating artery SubClassOf ObjectMinCardinality( connects artery ) and ObjectMaxCardinality( connects artery )
Added
- + communicating artery SubClassOf ObjectMinCardinality( connects artery ) and ObjectMaxCardinality( connects artery )

Changes for: interpedicular line

Deleted
- - interpedicular line EquivalentTo anatomical line and ObjectMinCardinality( connects pedicle of vertebra ) and ObjectMaxCardinality( connects pedicle of vertebra )
- - interpedicular line SubClassOf connects some pedicle of vertebra
Added
- + interpedicular line EquivalentTo anatomical line and ObjectMinCardinality( connects pedicle of vertebra ) and ObjectMaxCardinality( connects pedicle of vertebra )
- + interpedicular line SubClassOf connects some pedicle of vertebra

Changes for: ectopterygoid tooth

Deleted
- - ectopterygoid tooth EquivalentTo calcareous tooth and attaches to some ectopterygoid bone
- - ectopterygoid tooth SubClassOf attaches to some ectopterygoid bone
- - ectopterygoid tooth SubClassOf calcareous tooth
Added
- + ectopterygoid tooth EquivalentTo calcareous tooth and attaches to some ectopterygoid bone
- + ectopterygoid tooth SubClassOf attaches to some ectopterygoid bone
- + ectopterygoid tooth SubClassOf palatal tooth

Changes for: entopterygoid tooth

Deleted
- - entopterygoid tooth EquivalentTo calcareous tooth and attaches to some entopterygoid
- - entopterygoid tooth SubClassOf attaches to some entopterygoid
Added
- + entopterygoid tooth EquivalentTo calcareous tooth and attaches to some entopterygoid
- + entopterygoid tooth SubClassOf attaches to some entopterygoid

Changes for: dermis

Deleted
- - dermis comment Editor notes: Consider adding a layer-of-skin grouping class for all skin layers
Added
- + dermis editor note Consider adding a layer-of-skin grouping class for all skin layers

Changes for: premaxillary tooth

Deleted
- - premaxillary tooth EquivalentTo calcareous tooth and attaches to some premaxilla
- - premaxillary tooth SubClassOf attaches to some premaxilla
Added
- + premaxillary tooth EquivalentTo calcareous tooth and attaches to some premaxilla
- + premaxillary tooth SubClassOf attaches to some premaxilla

Changes for: embryonic structure

Deleted
- - embryonic structure database cross reference AEO:0000125

Changes for: mesethmoid-premaxillary joint

Deleted
- - mesethmoid-premaxillary joint EquivalentTo skeletal joint and connects some premaxilla and connects some mesethmoid bone
- - mesethmoid-premaxillary joint SubClassOf connects some mesethmoid bone
- - mesethmoid-premaxillary joint SubClassOf connects some premaxilla
Added
- + mesethmoid-premaxillary joint EquivalentTo skeletal joint and connects some premaxilla and connects some mesethmoid bone
- + mesethmoid-premaxillary joint SubClassOf connects some mesethmoid bone
- + mesethmoid-premaxillary joint SubClassOf connects some premaxilla

Changes for: mesethmoid-frontal joint

Deleted
- - mesethmoid-frontal joint EquivalentTo skeletal joint and connects some actinopterygian frontal bone and connects some mesethmoid bone
- - mesethmoid-frontal joint SubClassOf connects some actinopterygian frontal bone
- - mesethmoid-frontal joint SubClassOf connects some mesethmoid bone
Added
- + mesethmoid-frontal joint EquivalentTo skeletal joint and connects some actinopterygian frontal bone and connects some mesethmoid bone
- + mesethmoid-frontal joint SubClassOf connects some actinopterygian frontal bone
- + mesethmoid-frontal joint SubClassOf connects some mesethmoid bone

Changes for: mesethmoid-nasal joint

Deleted
- - mesethmoid-nasal joint EquivalentTo skeletal joint and connects some nasal bone and connects some mesethmoid bone
- - mesethmoid-nasal joint SubClassOf connects some mesethmoid bone
- - mesethmoid-nasal joint SubClassOf connects some nasal bone
Added
- + mesethmoid-nasal joint EquivalentTo skeletal joint and connects some nasal bone and connects some mesethmoid bone
- + mesethmoid-nasal joint SubClassOf connects some mesethmoid bone
- + mesethmoid-nasal joint SubClassOf connects some nasal bone

Changes for: mesethmoid-lateral ethmoid joint

Deleted
- - mesethmoid-lateral ethmoid joint EquivalentTo skeletal joint and connects some mesethmoid bone and connects some lateral ethmoid bone
- - mesethmoid-lateral ethmoid joint SubClassOf connects some lateral ethmoid bone
- - mesethmoid-lateral ethmoid joint SubClassOf connects some mesethmoid bone
Added
- + mesethmoid-lateral ethmoid joint EquivalentTo skeletal joint and connects some mesethmoid bone and connects some lateral ethmoid bone
- + mesethmoid-lateral ethmoid joint SubClassOf connects some lateral ethmoid bone
- + mesethmoid-lateral ethmoid joint SubClassOf connects some mesethmoid bone

Changes for: interchondral joint

Deleted
- - interchondral joint SubClassOf ObjectMinCardinality( connects rib ) and ObjectMaxCardinality( connects rib )
- - interchondral joint SubClassOf connects some rib
- - interchondral joint comment Editor notes: Consider creating logical definition after obo2owl cardinality tests. AO notes: FMA has both synovial and syndesmosis subtypes - consider adding separate class for FMA:7955 Synovial interchondral joint
Added
- + interchondral joint SubClassOf ObjectMinCardinality( connects rib ) and ObjectMaxCardinality( connects rib )
- + interchondral joint SubClassOf connects some rib
- + interchondral joint comment AO notes: FMA has both synovial and syndesmosis subtypes - consider adding separate class for FMA:7955 Synovial interchondral joint
- + interchondral joint editor note Consider creating logical definition after obo2owl cardinality tests

Changes for: joint of rib

Deleted
- - joint of rib EquivalentTo skeletal joint and connects some rib
- - joint of rib SubClassOf connects some rib
Added
- + joint of rib EquivalentTo skeletal joint and connects some rib
- + joint of rib SubClassOf connects some rib

Changes for: forelimb stylopod muscle

Deleted
- - forelimb stylopod muscle comment Editor notes: the FMA class “muscle of arm” belongs here, do not move. See notes on UBERON:0001460 for possible terminological confusion over term ‘arm’
Added
- + forelimb stylopod muscle comment See notes on UBERON:0001460 for possible terminological confusion over term ‘arm’
- + forelimb stylopod muscle editor note the FMA class ‘muscle of arm’ belongs here, do not move

Changes for: hindlimb zeugopod muscle

Deleted
- - hindlimb zeugopod muscle comment Editor notes: the FMA class “muscle of leg” belongs here, do not move. See notes on UBERON:0000978 for possible terminological confusion over term ‘leg’
Added
- + hindlimb zeugopod muscle comment See notes on UBERON:0000978 for possible terminological confusion over term ‘leg’
- + hindlimb zeugopod muscle editor note the FMA class ‘muscle of leg’ belongs here, do not move

Changes for: skin muscle

Deleted
- - skin muscle comment Editor notes: review as part of general integumentary system review - part of skin, or more generally, integumental system
Added
- + skin muscle editor note review as part of general integumentary system review - part of skin, or more generally, integumental system

Changes for: mesethmoid-vomer joint

Deleted
- - mesethmoid-vomer joint EquivalentTo skeletal joint and connects some vomer and connects some mesethmoid bone
- - mesethmoid-vomer joint SubClassOf connects some mesethmoid bone
- - mesethmoid-vomer joint SubClassOf connects some vomer
Added
- + mesethmoid-vomer joint EquivalentTo skeletal joint and connects some vomer and connects some mesethmoid bone
- + mesethmoid-vomer joint SubClassOf connects some mesethmoid bone
- + mesethmoid-vomer joint SubClassOf connects some vomer

Changes for: trabecular network of bone

Deleted
- - trabecular network of bone comment Editor note: consider revision - we have 3 classes, the tissue itself, the network, and the spaces.
Added
- + trabecular network of bone editor note consider revision - we have 3 classes, the tissue itself, the network, and the spaces.

Changes for: temporal part of head

Deleted
- - temporal part of head comment Editor notes: see UBERONREF:0000007 ‘temporal region’
Added
- + temporal part of head editor note see UBERONREF:0000007 ‘temporal region’

Changes for: amniotic ectoderm

Deleted
- - amniotic ectoderm SubClassOf extraembryonic tissue
- - amniotic ectoderm comment Editor note: we make the germ layer relationship develops_from, as currently the germ layers are declared to be purely embryonic. TODO - check. WP:Amnion - In the human embryo the earliest stages of the formation of the amnion have not been observed; in the youngest embryo which has been studied the amnion was already present as a closed sac, and appears in the inner cell-mass as a cavity. This cavity is roofed in by a single stratum of flattened, ectodermal cells, the amniotic ectoderm, and its floor consists of the prismatic ectoderm of the embryonic disk—the continuity between the roof and floor being established at the margin of the embryonic disk. Outside the amniotic ectoderm is a thin layer of mesoderm, which is continuous with that of the somatopleure and is connected by the body-stalk with the mesodermal lining of the chorion.
Added
- + amniotic ectoderm editor note we make the germ layer relationship develops_from, as currently the germ layers are declared to be purely embryonic. TODO - check. WP:Amnion - In the human embryo the earliest stages of the formation of the amnion have not been observed; in the youngest embryo which has been studied the amnion was already present as a closed sac, and appears in the inner cell-mass as a cavity. This cavity is roofed in by a single stratum of flattened, ectodermal cells, the amniotic ectoderm, and its floor consists of the prismatic ectoderm of the embryonic disk—the continuity between the roof and floor being established at the margin of the embryonic disk. Outside the amniotic ectoderm is a thin layer of mesoderm, which is continuous with that of the somatopleure and is connected by the body-stalk with the mesodermal lining of the chorion.

Changes for: placenta metrial gland

Added
- + placenta metrial gland SubClassOf extraembryonic structure

Changes for: rostral migratory stream

Deleted
- - rostral migratory stream SubClassOf connects some olfactory bulb
- - rostral migratory stream SubClassOf connects some postnatal subventricular zone
Added
- + rostral migratory stream SubClassOf connects some olfactory bulb
- + rostral migratory stream SubClassOf connects some postnatal subventricular zone

Changes for: amniotic mesoderm

Deleted
- - amniotic mesoderm SubClassOf extraembryonic tissue
- - amniotic mesoderm comment Editor note: we make the germ layer relationship develops_from, as currently the germ layers are declared to be purely embryonic. TODO - check. WP:Amnion - In the human embryo the earliest stages of the formation of the amnion have not been observed; in the youngest embryo which has been studied the amnion was already present as a closed sac, and appears in the inner cell-mass as a cavity. This cavity is roofed in by a single stratum of flattened, ectodermal cells, the amniotic ectoderm, and its floor consists of the prismatic ectoderm of the embryonic disk—the continuity between the roof and floor being established at the margin of the embryonic disk. Outside the amniotic ectoderm is a thin layer of mesoderm, which is continuous with that of the somatopleure and is connected by the body-stalk with the mesodermal lining of the chorion.
Added
- + amniotic mesoderm editor note we make the germ layer relationship develops_from, as currently the germ layers are declared to be purely embryonic. TODO - check. WP:Amnion - In the human embryo the earliest stages of the formation of the amnion have not been observed; in the youngest embryo which has been studied the amnion was already present as a closed sac, and appears in the inner cell-mass as a cavity. This cavity is roofed in by a single stratum of flattened, ectodermal cells, the amniotic ectoderm, and its floor consists of the prismatic ectoderm of the embryonic disk—the continuity between the roof and floor being established at the margin of the embryonic disk. Outside the amniotic ectoderm is a thin layer of mesoderm, which is continuous with that of the somatopleure and is connected by the body-stalk with the mesodermal lining of the chorion.

Changes for: tooth of upper jaw

Deleted
- - tooth of upper jaw comment Editor notes: Note that we follow EHDAA2 and consider teeth part of the jaw skeleton
Added
- + tooth of upper jaw editor note Note that we follow EHDAA2 and consider teeth part of the jaw skeleton

Changes for: chorionic mesenchyme

Deleted
- - chorionic mesenchyme SubClassOf extraembryonic tissue

Changes for: mesoderm of yolk sac

Deleted
- - mesoderm of yolk sac SubClassOf mixed endoderm/mesoderm-derived structure
Added
- + mesoderm of yolk sac SubClassOf extraembryonic tissue
- + mesoderm of yolk sac SubClassOf yolk sac endoderm

Changes for: trophectoderm

Deleted
- - trophectoderm comment Editor notes: distinction between trophectoderm and trophoblast unclear/inconsistent in many sources. AO notes: BTO has this has part of the trophoblast
Added
- + trophectoderm comment AO notes: BTO has this has part of the trophoblast
- + trophectoderm editor note distinction between trophectoderm and trophoblast unclear/inconsistent in many sources

Changes for: vault of skull

Deleted
- - vault of skull comment Editor notes: We follow http://www.ncbi.nlm.nih.gov/pubmed/11523816 (Morriss-Kay) in definingenumerating the components of the skull vault. Note that there is a conflict with Kardong; e.g. in fig 7.10, Kardong places the squamosal in the temporal series. We cannot place the vault as entirely part of the dermatocranium as it has a small splanchnocranium contribution and a sclerotomal contribution. Terminology notes. we include calvarium as a synonym, but Gray’s Anatomy’s list includes the Ethmoid and Sphenoid bone in the Calvaria. Some books (and HPO) state that calvaria consists of just the frontal bone, parietal bone, temporal bone, and occipital bone. Note vault may not be precisely equivalent to calvaria
Added
- + vault of skull comment Terminology notes. we include calvarium as a synonym, but Gray’s Anatomy’s list includes the Ethmoid and Sphenoid bone in the Calvaria. Some books (and HPO) state that calvaria consists of just the frontal bone, parietal bone, temporal bone, and occipital bone. Note vault may not be precisely equivalent to calvaria
- + vault of skull editor note We follow http://www.ncbi.nlm.nih.gov/pubmed/11523816 (Morriss-Kay) in definingenumerating the components of the skull vault. Note that there is a conflict with Kardong; e.g. in fig 7.10, Kardong places the squamosal in the temporal series. We cannot place the vault as entirely part of the dermatocranium as it has a small splanchnocranium contribution and a sclerotomal contribution

Changes for: metatarsophalangeal joint of pedal digit 5

Deleted
- - metatarsophalangeal joint of pedal digit 5 EquivalentTo skeletal joint and connects some metatarsal bone and connects some distal phalanx of pedal digit 5
- - metatarsophalangeal joint of pedal digit 5 SubClassOf connects some distal phalanx of pedal digit 5
- - metatarsophalangeal joint of pedal digit 5 SubClassOf connects some metatarsal bone
Added
- + metatarsophalangeal joint of pedal digit 5 EquivalentTo skeletal joint and connects some metatarsal bone and connects some distal phalanx of pedal digit 5
- + metatarsophalangeal joint of pedal digit 5 SubClassOf connects some distal phalanx of pedal digit 5
- + metatarsophalangeal joint of pedal digit 5 SubClassOf connects some metatarsal bone

Changes for: Reichert’s membrane

Added
- + Reichert’s membrane SubClassOf membranous layer
- + Reichert’s membrane SubClassOf part of some entire extraembryonic component

Changes for: extraembryonic ectoderm

Deleted
- - extraembryonic ectoderm comment Editor note: we make the germ layer relationship develops_from, as currently the germ layers are declared to be purely embryonic. TODO - check. WP:Amnion - In the human embryo the earliest stages of the formation of the amnion have not been observed; in the youngest embryo which has been studied the amnion was already present as a closed sac, and appears in the inner cell-mass as a cavity. This cavity is roofed in by a single stratum of flattened, ectodermal cells, the amniotic ectoderm, and its floor consists of the prismatic ectoderm of the embryonic disk—the continuity between the roof and floor being established at the margin of the embryonic disk. Outside the amniotic ectoderm is a thin layer of mesoderm, which is continuous with that of the somatopleure and is connected by the body-stalk with the mesodermal lining of the chorion.
Added
- + extraembryonic ectoderm editor note we make the germ layer relationship develops_from, as currently the germ layers are declared to be purely embryonic. TODO - check. WP:Amnion - In the human embryo the earliest stages of the formation of the amnion have not been observed; in the youngest embryo which has been studied the amnion was already present as a closed sac, and appears in the inner cell-mass as a cavity. This cavity is roofed in by a single stratum of flattened, ectodermal cells, the amniotic ectoderm, and its floor consists of the prismatic ectoderm of the embryonic disk—the continuity between the roof and floor being established at the margin of the embryonic disk. Outside the amniotic ectoderm is a thin layer of mesoderm, which is continuous with that of the somatopleure and is connected by the body-stalk with the mesodermal lining of the chorion.

Changes for: stylohyoid ligament

Deleted
- - stylohyoid ligament SubClassOf connects some hyoid bone lesser horn
- - stylohyoid ligament SubClassOf connects some styloid process of temporal bone
Added
- + stylohyoid ligament SubClassOf connects some hyoid bone lesser horn
- + stylohyoid ligament SubClassOf connects some styloid process of temporal bone

Changes for: interphalangeal joint of manus

Deleted
- - interphalangeal joint of manus SubClassOf ObjectMinCardinality( connects phalanx of manus ) and ObjectMaxCardinality( connects phalanx of manus )
- - interphalangeal joint of manus SubClassOf connects some phalanx of manus
- - interphalangeal joint of manus comment Editor notes: consider renaming: ‘finger’ is ambiguous as the term in some usages excludes the thumb (we include it)
Added
- + interphalangeal joint of manus SubClassOf ObjectMinCardinality( connects phalanx of manus ) and ObjectMaxCardinality( connects phalanx of manus )
- + interphalangeal joint of manus SubClassOf connects some phalanx of manus
- + interphalangeal joint of manus editor note consider renaming: ‘finger’ is ambiguous as the term in some usages excludes the thumb (we include it)

Changes for: interphalangeal joint of pes

Deleted
- - interphalangeal joint of pes SubClassOf ObjectMinCardinality( connects phalanx of pes ) and ObjectMaxCardinality( connects phalanx of pes )
- - interphalangeal joint of pes SubClassOf connects some phalanx of pes
Added
- + interphalangeal joint of pes SubClassOf ObjectMinCardinality( connects phalanx of pes ) and ObjectMaxCardinality( connects phalanx of pes )
- + interphalangeal joint of pes SubClassOf connects some phalanx of pes

Changes for: interphalangeal joint of pedal digit 3

Deleted
- - interphalangeal joint of pedal digit 3 SubClassOf ObjectMinCardinality( connects pedal digit 3 phalanx ) and ObjectMaxCardinality( connects pedal digit 3 phalanx )
Added
- + interphalangeal joint of pedal digit 3 SubClassOf ObjectMinCardinality( connects pedal digit 3 phalanx ) and ObjectMaxCardinality( connects pedal digit 3 phalanx )

Changes for: interphalangeal joint of pedal digit 2

Deleted
- - interphalangeal joint of pedal digit 2 SubClassOf ObjectMinCardinality( connects pedal digit 2 phalanx ) and ObjectMaxCardinality( connects pedal digit 2 phalanx )
Added
- + interphalangeal joint of pedal digit 2 SubClassOf ObjectMinCardinality( connects pedal digit 2 phalanx ) and ObjectMaxCardinality( connects pedal digit 2 phalanx )

Changes for: interphalangeal joint of pedal digit 1

Deleted
- - interphalangeal joint of pedal digit 1 SubClassOf ObjectMinCardinality( connects pedal digit 1 phalanx ) and ObjectMaxCardinality( connects pedal digit 1 phalanx )
Added
- + interphalangeal joint of pedal digit 1 SubClassOf ObjectMinCardinality( connects pedal digit 1 phalanx ) and ObjectMaxCardinality( connects pedal digit 1 phalanx )

Changes for: interphalangeal joint of manual digit 1

Deleted
- - interphalangeal joint of manual digit 1 SubClassOf ObjectMinCardinality( connects manual digit 1 phalanx ) and ObjectMaxCardinality( connects manual digit 1 phalanx )
Added
- + interphalangeal joint of manual digit 1 SubClassOf ObjectMinCardinality( connects manual digit 1 phalanx ) and ObjectMaxCardinality( connects manual digit 1 phalanx )

Changes for: interphalangeal joint of manual digit 2

Deleted
- - interphalangeal joint of manual digit 2 SubClassOf ObjectMinCardinality( connects pedal digit 2 phalanx ) and ObjectMaxCardinality( connects pedal digit 2 phalanx )
Added
- + interphalangeal joint of manual digit 2 SubClassOf ObjectMinCardinality( connects pedal digit 2 phalanx ) and ObjectMaxCardinality( connects pedal digit 2 phalanx )

Changes for: interphalangeal joint of pedal digit 4

Deleted
- - interphalangeal joint of pedal digit 4 SubClassOf ObjectMinCardinality( connects pedal digit 4 phalanx ) and ObjectMaxCardinality( connects pedal digit 4 phalanx )
Added
- + interphalangeal joint of pedal digit 4 SubClassOf ObjectMinCardinality( connects pedal digit 4 phalanx ) and ObjectMaxCardinality( connects pedal digit 4 phalanx )

Changes for: interphalangeal joint of pedal digit 5

Deleted
- - interphalangeal joint of pedal digit 5 SubClassOf ObjectMinCardinality( connects pedal digit 5 phalanx ) and ObjectMaxCardinality( connects pedal digit 5 phalanx )
Added
- + interphalangeal joint of pedal digit 5 SubClassOf ObjectMinCardinality( connects pedal digit 5 phalanx ) and ObjectMaxCardinality( connects pedal digit 5 phalanx )

Changes for: interphalangeal joint of manual digit 4

Deleted
- - interphalangeal joint of manual digit 4 SubClassOf ObjectMinCardinality( connects pedal digit 4 phalanx ) and ObjectMaxCardinality( connects pedal digit 4 phalanx )
Added
- + interphalangeal joint of manual digit 4 SubClassOf ObjectMinCardinality( connects pedal digit 4 phalanx ) and ObjectMaxCardinality( connects pedal digit 4 phalanx )

Changes for: interphalangeal joint of manual digit 3

Deleted
- - interphalangeal joint of manual digit 3 SubClassOf ObjectMinCardinality( connects pedal digit 3 phalanx ) and ObjectMaxCardinality( connects pedal digit 3 phalanx )
Added
- + interphalangeal joint of manual digit 3 SubClassOf ObjectMinCardinality( connects pedal digit 3 phalanx ) and ObjectMaxCardinality( connects pedal digit 3 phalanx )

Changes for: life cycle stage

Deleted
- - life cycle stage comment Editor notes: we map the ZFS unknown stage here as it is logically equivalent to saying some life cycle stage
Added
- + life cycle stage editor note we map the ZFS unknown stage here as it is logically equivalent to saying some life cycle stage

Changes for: interphalangeal joint of manual digit 5

Deleted
- - interphalangeal joint of manual digit 5 SubClassOf ObjectMinCardinality( connects pedal digit 5 phalanx ) and ObjectMaxCardinality( connects pedal digit 5 phalanx )
Added
- + interphalangeal joint of manual digit 5 SubClassOf ObjectMinCardinality( connects pedal digit 5 phalanx ) and ObjectMaxCardinality( connects pedal digit 5 phalanx )

Changes for: metacarpophalangeal joint of manual digit 1

Deleted
- - metacarpophalangeal joint of manual digit 1 EquivalentTo skeletal joint and connects some metacarpal bone and connects some proximal phalanx of manual digit 1
- - metacarpophalangeal joint of manual digit 1 SubClassOf connects some metacarpal bone
- - metacarpophalangeal joint of manual digit 1 SubClassOf connects some proximal phalanx of manual digit 1
Added
- + metacarpophalangeal joint of manual digit 1 EquivalentTo skeletal joint and connects some metacarpal bone and connects some proximal phalanx of manual digit 1
- + metacarpophalangeal joint of manual digit 1 SubClassOf connects some metacarpal bone
- + metacarpophalangeal joint of manual digit 1 SubClassOf connects some proximal phalanx of manual digit 1

Changes for: blastula stage

Deleted
- - blastula stage comment Editor note: consider adding a preceding stage ‘morula stage’ as part of cleavage
Added
- + blastula stage editor note consider adding a preceding stage ‘morula stage’ as part of cleavage

Changes for: metacarpophalangeal joint of manual digit 2

Deleted
- - metacarpophalangeal joint of manual digit 2 EquivalentTo skeletal joint and connects some metacarpal bone and connects some proximal phalanx of manual digit 2
- - metacarpophalangeal joint of manual digit 2 SubClassOf connects some metacarpal bone
- - metacarpophalangeal joint of manual digit 2 SubClassOf connects some proximal phalanx of manual digit 2
Added
- + metacarpophalangeal joint of manual digit 2 EquivalentTo skeletal joint and connects some metacarpal bone and connects some proximal phalanx of manual digit 2
- + metacarpophalangeal joint of manual digit 2 SubClassOf connects some metacarpal bone
- + metacarpophalangeal joint of manual digit 2 SubClassOf connects some proximal phalanx of manual digit 2

Changes for: metacarpophalangeal joint of manual digit 5

Deleted
- - metacarpophalangeal joint of manual digit 5 EquivalentTo skeletal joint and connects some metacarpal bone and connects some proximal phalanx of manual digit 5
- - metacarpophalangeal joint of manual digit 5 SubClassOf connects some metacarpal bone
- - metacarpophalangeal joint of manual digit 5 SubClassOf connects some proximal phalanx of manual digit 5
Added
- + metacarpophalangeal joint of manual digit 5 EquivalentTo skeletal joint and connects some metacarpal bone and connects some proximal phalanx of manual digit 5
- + metacarpophalangeal joint of manual digit 5 SubClassOf connects some metacarpal bone
- + metacarpophalangeal joint of manual digit 5 SubClassOf connects some proximal phalanx of manual digit 5

Changes for: metacarpophalangeal joint of manual digit 4

Deleted
- - metacarpophalangeal joint of manual digit 4 EquivalentTo skeletal joint and connects some metacarpal bone and connects some proximal phalanx of manual digit 4
- - metacarpophalangeal joint of manual digit 4 SubClassOf connects some metacarpal bone
- - metacarpophalangeal joint of manual digit 4 SubClassOf connects some proximal phalanx of manual digit 4
Added
- + metacarpophalangeal joint of manual digit 4 EquivalentTo skeletal joint and connects some metacarpal bone and connects some proximal phalanx of manual digit 4
- + metacarpophalangeal joint of manual digit 4 SubClassOf connects some metacarpal bone
- + metacarpophalangeal joint of manual digit 4 SubClassOf connects some proximal phalanx of manual digit 4

Changes for: metacarpophalangeal joint of manual digit 3

Deleted
- - metacarpophalangeal joint of manual digit 3 EquivalentTo skeletal joint and connects some metacarpal bone and connects some proximal phalanx of manual digit 3
- - metacarpophalangeal joint of manual digit 3 SubClassOf connects some metacarpal bone
- - metacarpophalangeal joint of manual digit 3 SubClassOf connects some proximal phalanx of manual digit 3
Added
- + metacarpophalangeal joint of manual digit 3 EquivalentTo skeletal joint and connects some metacarpal bone and connects some proximal phalanx of manual digit 3
- + metacarpophalangeal joint of manual digit 3 SubClassOf connects some metacarpal bone
- + metacarpophalangeal joint of manual digit 3 SubClassOf connects some proximal phalanx of manual digit 3

Changes for: metatarsophalangeal joint of pedal digit 3

Deleted
- - metatarsophalangeal joint of pedal digit 3 EquivalentTo skeletal joint and connects some metatarsal bone and connects some distal phalanx of pedal digit 3
- - metatarsophalangeal joint of pedal digit 3 SubClassOf connects some distal phalanx of pedal digit 3
- - metatarsophalangeal joint of pedal digit 3 SubClassOf connects some metatarsal bone
Added
- + metatarsophalangeal joint of pedal digit 3 EquivalentTo skeletal joint and connects some metatarsal bone and connects some distal phalanx of pedal digit 3
- + metatarsophalangeal joint of pedal digit 3 SubClassOf connects some distal phalanx of pedal digit 3
- + metatarsophalangeal joint of pedal digit 3 SubClassOf connects some metatarsal bone

Changes for: metatarsophalangeal joint of pedal digit 4

Deleted
- - metatarsophalangeal joint of pedal digit 4 EquivalentTo skeletal joint and connects some metatarsal bone and connects some distal phalanx of pedal digit 4
- - metatarsophalangeal joint of pedal digit 4 SubClassOf connects some distal phalanx of pedal digit 4
- - metatarsophalangeal joint of pedal digit 4 SubClassOf connects some metatarsal bone
Added
- + metatarsophalangeal joint of pedal digit 4 EquivalentTo skeletal joint and connects some metatarsal bone and connects some distal phalanx of pedal digit 4
- + metatarsophalangeal joint of pedal digit 4 SubClassOf connects some distal phalanx of pedal digit 4
- + metatarsophalangeal joint of pedal digit 4 SubClassOf connects some metatarsal bone

Changes for: metatarsophalangeal joint of pedal digit 2

Deleted
- - metatarsophalangeal joint of pedal digit 2 EquivalentTo skeletal joint and connects some metatarsal bone and connects some distal phalanx of pedal digit 2
- - metatarsophalangeal joint of pedal digit 2 SubClassOf connects some distal phalanx of pedal digit 2
- - metatarsophalangeal joint of pedal digit 2 SubClassOf connects some metatarsal bone
Added
- + metatarsophalangeal joint of pedal digit 2 EquivalentTo skeletal joint and connects some metatarsal bone and connects some distal phalanx of pedal digit 2
- + metatarsophalangeal joint of pedal digit 2 SubClassOf connects some distal phalanx of pedal digit 2
- + metatarsophalangeal joint of pedal digit 2 SubClassOf connects some metatarsal bone

Changes for: metatarsophalangeal joint of pedal digit 1

Deleted
- - metatarsophalangeal joint of pedal digit 1 EquivalentTo skeletal joint and connects some metatarsal bone and connects some distal phalanx of pedal digit 1
- - metatarsophalangeal joint of pedal digit 1 SubClassOf connects some distal phalanx of pedal digit 1
- - metatarsophalangeal joint of pedal digit 1 SubClassOf connects some metatarsal bone
Added
- + metatarsophalangeal joint of pedal digit 1 EquivalentTo skeletal joint and connects some metatarsal bone and connects some distal phalanx of pedal digit 1
- + metatarsophalangeal joint of pedal digit 1 SubClassOf connects some distal phalanx of pedal digit 1
- + metatarsophalangeal joint of pedal digit 1 SubClassOf connects some metatarsal bone

Changes for: dorsal anterior lateral line ganglion

Deleted
- - dorsal anterior lateral line ganglion has obo namespace uberon/phenoscape-anatomy
Added
- + dorsal anterior lateral line ganglion has obo namespace uberon

Changes for: tract of brain

Deleted
- - tract of brain comment Editor notes: the NIFSTD class ‘nerve tract’ is classified under ‘regional part of brain’, so it may seem like it belongs here, but actually includes spinal cord tracts
Added
- + tract of brain editor note the NIFSTD class ‘nerve tract’ is classified under ‘regional part of brain’, so it may seem like it belongs here, but actually includes spinal cord tracts

Changes for: anal canal

Deleted
- - anal canal comment Editor notes: requires alignment with EHDAA2 and complete developmental relationships
Added
- + anal canal editor note requires alignment with EHDAA2 and complete developmental relationships

Changes for: mouth

Deleted
- - mouth definition The proximal portion of the digestive tract, containing the oral cavity and bounded by the oral opening. In vertebrates, this extends to the pharynx and includes teeth, gums, lips, tongue and parts of the palate. { database cross reference=http://en.wikipedia.org/wiki/Mouth , database cross reference=https://github.com/obophenotype/uberon/wiki/The-digestive-tract }
Added
- + mouth definition The proximal portion of the digestive tract, containing the oral cavity and bounded by the oral opening. In vertebrates, this extends to the pharynx and includes gums, lips, tongue and parts of the palate. Typically also includes the teeth, except where these occur elsewhere (e.g. pharyngeal jaws) or protrude from the mouth (tusks). { database cross reference=http://en.wikipedia.org/wiki/Mouth , database cross reference=https://github.com/obophenotype/uberon/wiki/The-digestive-tract }

Changes for: intestine

Deleted
- - intestine comment Editor notes: This class is probably too inclusive. Taxon notes: [in zebrafish] No stomach, small intestine, or large intestine can be distinguished. However, differences can be found in the morphology of the mucosa columnar epithelial cells and the number of goblet cells, suggesting functional differentiation. The intestine has numerous folds that become progressively shorter in a rostral-to-caudal direction. Proportionally, these folds are significantly larger than the finger-like intestinal villi of mammals and other amniotes (Wallace et al. 2005). Columnar-shaped absorptive enterocytes are the most numerous in the zebrafish intestinal epithelium. Goblet cells are the second most populous epithelial cell type.
Added
- + intestine comment No stomach, small intestine, or large intestine can be distinguished. However, differences can be found in the morphology of the mucosa columnar epithelial cells and the number of goblet cells, suggesting functional differentiation. The intestine has numerous folds that become progressively shorter in a rostral-to-caudal direction. Proportionally, these folds are significantly larger than the finger-like intestinal villi of mammals and other amniotes (Wallace et al. 2005). Columnar-shaped absorptive enterocytes are the most numerous in the zebrafish intestinal epithelium. Goblet cells are the second most populous epithelial cell type.
- + intestine editor note This class is probably too inclusive. Taxon notes: [in zebrafish]

Changes for: haemolymphatic fluid

Deleted
- - haemolymphatic fluid EquivalentTo portion of organism substance and part of some hematopoietic system
- - haemolymphatic fluid SubClassOf part of some hematopoietic system
Added
- + haemolymphatic fluid EquivalentTo portion of organism substance and part of some hemolymphoid system
- + haemolymphatic fluid SubClassOf part of some hemolymphoid system

Changes for: parietal endoderm

Deleted
- - parietal endoderm SubClassOf extraembryonic structure
Added
- + parietal endoderm SubClassOf part of some entire extraembryonic component
- + parietal endoderm SubClassOf transitional anatomical structure

Changes for: meninx of midbrain

Deleted
- - meninx of midbrain comment Editor notes: consider changing genus to subdivision of meninx
Added
- + meninx of midbrain editor note consider changing genus to subdivision of meninx

Changes for: meninx of telencephalon

Deleted
- - meninx of telencephalon comment Editor notes: consider changing genus to subdivision of meninx
Added
- + meninx of telencephalon editor note consider changing genus to subdivision of meninx

Changes for: meninx of hindbrain

Deleted
- - meninx of hindbrain comment Editor notes: consider changing genus to subdivision of meninx
Added
- + meninx of hindbrain editor note consider changing genus to subdivision of meninx

Changes for: meninx of diencephalon

Deleted
- - meninx of diencephalon comment Editor notes: consider changing genus to subdivision of meninx
Added
- + meninx of diencephalon editor note consider changing genus to subdivision of meninx

Changes for: metapodial pad

Deleted
- - metapodial pad comment Editor notes: check synonyms - re footpad
Added
- + metapodial pad editor note check synonyms - re footpad

Changes for: skeletal ligament

Deleted
- - skeletal ligament EquivalentTo ligament and part of some skeletal system and connects some skeletal element
- - skeletal ligament SubClassOf connects some skeletal element
- - skeletal ligament comment Editor notes: logical definition deliberately made strict to avoid classifying MA:spiral ligament as both nonskeletal and skeletal. see https://sourceforge.net/tracker/?group_id=76834&atid=1205376
Added
- + skeletal ligament EquivalentTo ligament and part of some skeletal system and connects some skeletal element
- + skeletal ligament SubClassOf connects some skeletal element
- + skeletal ligament editor note logical definition deliberately made strict to avoid classifying MA:spiral ligament as both nonskeletal and skeletal. see https://sourceforge.net/tracker/?group_id=76834&atid=1205376

Changes for: smooth muscle of eye

Deleted
- - smooth muscle of eye comment 331. Includes ciliary and iris smooth muscle
Added
- + smooth muscle of eye editor note 331. Includes ciliary and iris smooth muscle

Changes for: periosteum of epiphysis

Deleted
- - periosteum of epiphysis SubClassOf periosteum
Added
- + periosteum of epiphysis SubClassOf periosteum of long bone

Changes for: epithelium of rectum

Deleted
- - epithelium of rectum database cross reference WBbt:0005800
Added
- + epithelium of rectum SubClassOf epithelium of terminal part of digestive tract

Changes for: mesenchyme of yolk sac

Deleted
- - mesenchyme of yolk sac SubClassOf mixed endoderm/mesoderm-derived structure
Added
- + mesenchyme of yolk sac SubClassOf yolk sac endoderm

Changes for: ligamentum arteriosum

Added
- + ligamentum arteriosum see also recurrent laryngeal nerve

Changes for: future meninx

Deleted
- - future meninx comment Editor notes: decide whether to treat the endo and ecto meninx as subtypes or parts of the future meninx
Added
- + future meninx editor note decide whether to treat the endo and ecto meninx as subtypes or parts of the future meninx

Changes for: metacarpus region

Deleted
- - metacarpus region comment Editor notes: Note that along with FMA we treat this as a limb segment rather than a purely skeletal element. AO notes: Note that mammalian and non-mammalian AOs differ in whether they consider this a part of the skeleton
Added
- + metacarpus region comment AO notes: Note that mammalian and non-mammalian AOs differ in whether they consider this a part of the skeleton
- + metacarpus region editor note Note that along with FMA we treat this as a limb segment rather than a purely skeletal element

Changes for: cavity lining

Deleted
- - cavity lining comment Editor notes: consider merging with serous membrane. AO notes: in MA this groups pericardium, pleura and periotoneal cavity lining
Added
- + cavity lining comment AO notes: in MA this groups pericardium, pleura and periotoneal cavity lining
- + cavity lining editor note consider merging with serous membrane

Changes for: entire sense organ system

Added
- + entire sense organ system SubClassOf existence ends during some fully formed stage

Changes for: ligament

Added
- + ligament database cross reference FMA:30319

Changes for: atlanto-occipital joint

Deleted
- - atlanto-occipital joint SubClassOf connects some occipital bone
- - atlanto-occipital joint SubClassOf connects some vertebral bone 1
Added
- + atlanto-occipital joint SubClassOf connects some occipital bone
- + atlanto-occipital joint SubClassOf connects some vertebral bone 1

Changes for: anatomical projection

Deleted
- - anatomical projection comment Editor notes: should be declared sijoint from organ, but in some ontologies (e.g. ZFA), structures such as neural spines are classified as bones (and hence organs)
Added
- + anatomical projection editor note should be declared sijoint from organ, but in some ontologies (e.g. ZFA), structures such as neural spines are classified as bones (and hence organs)

Changes for: anterior commissure anterior part

Deleted
- - anterior commissure anterior part EquivalentTo nervous system commissure and part of some anterior commissure and connects some olfactory bulb
- - anterior commissure anterior part SubClassOf connects some olfactory bulb
Added
- + anterior commissure anterior part EquivalentTo nervous system commissure and part of some anterior commissure and connects some olfactory bulb
- + anterior commissure anterior part SubClassOf connects some olfactory bulb

Changes for: pontine tegmentum

Added
- + pontine tegmentum has exact synonym dorsal pons

Changes for: regenerating anatomical structure

Deleted
- - regenerating anatomical structure comment Editor notes: we define this in terms of active participation in regeneration, rather that capabilities. In this sense it is different from the AEO structure.
Added
- + regenerating anatomical structure editor note we define this in terms of active participation in regeneration, rather that capabilities. In this sense it is different from the AEO structure.

Changes for: subdivision of vertebral column

Added
- + subdivision of vertebral column has exact synonym vertebrae series
- + subdivision of vertebral column has exact synonym vertebral series

Changes for: caudal region of vertebral column

Added
- + caudal region of vertebral column has exact synonym caudal vertebrae series { database cross reference=http://purl.bioontology.org/ontology/provisional/a047a2d5-418f-4d9c-ad21-ee0b7c29c29d }

Changes for: sacral region of vertebral column

Added
- + sacral region of vertebral column has exact synonym sacral vertebrae series

Changes for: lumbar region of vertebral column

Added
- + lumbar region of vertebral column has exact synonym lumbar vertebrae series

Changes for: thoracic region of vertebral column

Added
- + thoracic region of vertebral column has exact synonym thoracic vertebrae series

Changes for: cervical region of vertebral column

Added
- + cervical region of vertebral column has exact synonym cervical vertebrae series

Changes for: process of vertebra

Added
- + process of vertebra database cross reference AAO:0000739
- + process of vertebra has narrow synonym spinous process { database cross reference=AAO:0000739 }

Changes for: posterior part of anterior commissure

Deleted
- - posterior part of anterior commissure EquivalentTo nervous system commissure and part of some anterior commissure and connects some temporal lobe
- - posterior part of anterior commissure SubClassOf connects some left temporal lobe
- - posterior part of anterior commissure SubClassOf connects some right temporal lobe
- - posterior part of anterior commissure SubClassOf connects some temporal lobe
Added
- + posterior part of anterior commissure EquivalentTo nervous system commissure and part of some anterior commissure and connects some temporal lobe
- + posterior part of anterior commissure SubClassOf connects some left temporal lobe
- + posterior part of anterior commissure SubClassOf connects some right temporal lobe
- + posterior part of anterior commissure SubClassOf connects some temporal lobe

Changes for: midbrain-hindbrain boundary

Deleted
- - midbrain-hindbrain boundary comment editor note: consider adding class for organizer. Consider adding separate class for isthmus as a structure
Added
- + midbrain-hindbrain boundary editor note consider adding class for organizer. Consider adding separate class for isthmus as a structure

Changes for: heart primordium

Deleted
- - heart primordium comment editor note: should probably be merged with heart rudiment.
Added
- + heart primordium editor note should probably be merged with heart rudiment.

Changes for: anterior neural tube

Deleted
- - anterior neural tube comment editor note: TODO - add grouping class for the anterior end of the neural tube at all stages
Added
- + anterior neural tube editor note TODO - add grouping class for the anterior end of the neural tube at all stages

Changes for: dorsal fin

Deleted
- - dorsal fin SubClassOf fin
Added
- + dorsal fin SubClassOf median fin

Changes for: dermatocranium

Deleted
- - dermatocranium comment Editor notes: wikipedia treats skull roof and dermatocranium as synonymous, but some sources treat the roof as being part of the dermatocranium - see UBERONREF:0000007
Added
- + dermatocranium editor note wikipedia treats skull roof and dermatocranium as synonymous, but some sources treat the roof as being part of the dermatocranium - see UBERONREF:0000007

Changes for: suspensorium

Deleted
- - suspensorium comment Editor notes: requires review, possible split; TAO/ZFA structure is splanchoncranium (but includes some dermal bones as parts). Note AAO also includes ‘palatoquadrate and suspensorium’ as a class
Added
- + suspensorium editor note requires review, possible split; TAO/ZFA structure is splanchoncranium (but includes some dermal bones as parts). Note AAO also includes ‘palatoquadrate and suspensorium’ as a class

Changes for: keratin-based acellular structure

Deleted
- - keratin-based acellular structure comment Editor note: should all structures composed primarily of keratin be classified here? At what stage of cornification are keratin-filled cells no longer considered cells
Added
- + keratin-based acellular structure editor note should all structures composed primarily of keratin be classified here? At what stage of cornification are keratin-filled cells no longer considered cells

Changes for: mammalian cervical vertebra 3

Added
- + mammalian cervical vertebra 3 has exact synonym cervical vertebrae 3 { database cross reference=UBERONTEMP:aeb6ac70-fd18-403d-a0b9-dd03942c7812 }
- + mammalian cervical vertebra 3 has exact synonym third cervical vertebra of axial skeleton { database cross reference=UBERONTEMP:aeb6ac70-fd18-403d-a0b9-dd03942c7812 }

Changes for: equine glandular stomach

Deleted
- - equine glandular stomach comment Editor notes: We have a distinct class for ‘glandular region of stomach’. We may want to merge into this class, even though this is not considered a distinct stomach.
Added
- + equine glandular stomach editor note We have a distinct class for ‘glandular region of stomach’. We may want to merge into this class, even though this is not considered a distinct stomach.

Changes for: prepupa

Deleted
- - prepupa SubClassOf develops from some larva
Added
- + prepupa SubClassOf immediate transformation of some larva

Changes for: fascia

Deleted
- - fascia SubClassOf ObjectMinCardinality( connects muscle organ ) and ObjectMaxCardinality( connects muscle organ )
- - fascia SubClassOf connects some muscle organ
Added
- + fascia SubClassOf ObjectMinCardinality( connects muscle organ ) and ObjectMaxCardinality( connects muscle organ )
- + fascia SubClassOf connects some muscle organ

Changes for: arthropod hypopharynx

Deleted
- - arthropod hypopharynx comment Editor notes: this term should be ceded to the arthropod anatomy ontology
Added
- + arthropod hypopharynx editor note this term should be ceded to the arthropod anatomy ontology

Changes for: arthropod tibia

Deleted
- - arthropod tibia comment Editor notes: this term should be ceded to the arthropod anatomy ontology. Homology notes: homology of leg segments between groups are difficult to prove and are the source of much argument. Some authors posit up to eleven segments per leg for the most recent common ancestor of extant arthropods [1], but modern arthropods have eight or fewer. It has been argued [2][3] that the ancestral leg need not have been so complex, and that other events, such as the successive loss of function of a Hox-gene could result in parallel gains of leg segments.
Added
- + arthropod tibia comment that the ancestral leg need not have been so complex, and that other events, such as the successive loss of function of a Hox-gene could result in parallel gains of leg segments.
- + arthropod tibia editor note this term should be ceded to the arthropod anatomy ontology. Homology notes: homology of leg segments between groups are difficult to prove and are the source of much argument. Some authors posit up to eleven segments per leg for the most recent common ancestor of extant arthropods [1], but modern arthropods have eight or fewer. It has been argued [2][3]

Changes for: arthropod sternum

Deleted
- - arthropod sternum comment Editor notes: this term should be ceded to the arthropod anatomy ontology
Added
- + arthropod sternum editor note this term should be ceded to the arthropod anatomy ontology

Changes for: gastro-splenic ligament

Deleted
- - gastro-splenic ligament SubClassOf connects some spleen
- - gastro-splenic ligament SubClassOf connects some stomach
Added
- + gastro-splenic ligament SubClassOf connects some spleen
- + gastro-splenic ligament SubClassOf connects some stomach

Changes for: tendon

Deleted
- - tendon SubClassOf connects some bone element
- - tendon SubClassOf connects some muscle organ
Added
- + tendon SubClassOf connects some bone element
- + tendon SubClassOf connects some muscle organ

Changes for: choledocho-duodenal junction

Deleted
- - choledocho-duodenal junction EquivalentTo anatomical junction and connects some duodenum and connects some bile duct
- - choledocho-duodenal junction SubClassOf connects some bile duct
- - choledocho-duodenal junction SubClassOf connects some duodenum
Added
- + choledocho-duodenal junction EquivalentTo anatomical junction and connects some duodenum and connects some bile duct
- + choledocho-duodenal junction SubClassOf connects some bile duct
- + choledocho-duodenal junction SubClassOf connects some duodenum

Changes for: camera-type eye

Added
- + camera-type eye SubClassOf existence ends during some fully formed stage

Changes for: forelimb bone

Deleted
- - forelimb bone definition A bone that is part of a forelimb region. Examples: any manus phalanx, humerus. Counter-examples: scapula (it is part of the pectoral girdle) { database cross reference=https://orcid.org/0000-0002-6601-2165 }
Added
- + forelimb bone definition A bone that is part of a forelimb region. Examples: humerus, any of the phalanges. Counter-example: scapula (a bone of the pectoral girdle). Note that we consider the forelimb to end at the shoulder. { database cross reference=https://orcid.org/0000-0002-6601-2165 }

Changes for: extraembryonic endoderm

Added
- + extraembryonic endoderm SubClassOf part of some entire extraembryonic component

Changes for: upper lobe of lung

Deleted
- - upper lobe of lung comment Editor notes: the logical definition must have a clause stating position relative to a lower lobe, otherwise a single lobed side (such as the left lobe in the mouse) trivially classifies as an upper lobe
Added
- + upper lobe of lung editor note the logical definition must have a clause stating position relative to a lower lobe, otherwise a single lobed side (such as the left lobe in the mouse) trivially classifies as an upper lobe

Changes for: lower lobe of lung

Deleted
- - lower lobe of lung comment Editor notes: defining lobes spatially across species
Added
- + lower lobe of lung editor note defining lobes spatially across species

Changes for: external ectoderm

Deleted
- - external ectoderm comment Editor note: merge with non-neural. In vertebrates, the ectoderm has three parts: external ectoderm (also known as surface ectoderm), the neurectoderm (neural crest, and neural tube). Development notes: (or external ectoderm) forms the following structures: Skin Epithelium of the mouth and nasal cavity saliavary glands, and glands of mouth and nasal cavity Enamel - as a side note dentin and dental pulp are formed from ectomesenchyme which is derived from ectoderm Epithelium of pineal and pituitary glands Lens and cornea of the eye Apical ectodermal ridge inducing development of the limb buds of the embryo. Sensory receptors in epidermis
Added
- + external ectoderm comment Development notes: (or external ectoderm) forms the following structures: Skin Epithelium of the mouth and nasal cavity saliavary glands, and glands of mouth and nasal cavity Enamel - as a side note dentin and dental pulp are formed from ectomesenchyme which is derived from ectoderm Epithelium of pineal and pituitary glands Lens and cornea of the eye Apical ectodermal ridge inducing development of the limb buds of the embryo. Sensory receptors in epidermis
- + external ectoderm editor note merge with non-neural. In vertebrates, the ectoderm has three parts: external ectoderm (also known as surface ectoderm), the neurectoderm (neural crest, and neural tube)

Changes for: metanephros

Added
- + metanephros SubClassOf existence ends during some fully formed stage

Changes for: perichordal bone

Deleted
- - perichordal bone comment Editor notes: We go with the latest VSAO in making this a subtype of bone, and add a logical definition based on the textual definition in VSAO. We also include the subtyping under ‘replacement bone’, for consistency with ZFA
Added
- + perichordal bone editor note We go with the latest VSAO in making this a subtype of bone, and add a logical definition based on the textual definition in VSAO. We also include the subtyping under ‘replacement bone’, for consistency with ZFA

Changes for: tricuspid valve cusp

Deleted
- - tricuspid valve cusp comment Editor notes: check whether we need to separate cusp/leaflet/valve
Added
- + tricuspid valve cusp editor note check whether we need to separate cusp/leaflet/valve

Changes for: insect labrum

Deleted
- - insect labrum comment Editor notes: this term should be ceded to the arthropod anatomy ontology
Added
- + insect labrum editor note this term should be ceded to the arthropod anatomy ontology

Changes for: head mesenchyme from mesoderm

Deleted
- - head mesenchyme from mesoderm comment Editor note: merged in ‘head mesoderm’ from XAO/AAO and EFO here. Partially implements UBERONREF:0000002 NC meeting scheme
Added
- + head mesenchyme from mesoderm editor note merged in ‘head mesoderm’ from XAO/AAO and EFO here. Partially implements UBERONREF:0000002 NC meeting scheme

Changes for: mandibular prominence

Deleted
- - mandibular prominence comment Editor note: check develops_from
Added
- + mandibular prominence editor note check develops_from

Changes for: stomach glandular epithelium

Deleted
- - stomach glandular epithelium comment Editor notes: we follow Kardong in treating the glandular epithelium as a distinct entity, and thus as an epithelium which has glands; FMA has ‘epithelium of gastric gland’, which is part of the gastric gland. Consider also: stomach glandular region as a part-of parent
Added
- + stomach glandular epithelium editor note we follow Kardong in treating the glandular epithelium as a distinct entity, and thus as an epithelium which has glands; FMA has ‘epithelium of gastric gland’, which is part of the gastric gland. Consider also: stomach glandular region as a part-of parent

Changes for: cuneate fasciculus of spinal cord

Deleted
- - cuneate fasciculus of spinal cord comment editor note: check ontology structure, isa parentage to fasciculus of spinal cord should be inferred. TODO - change definition to be the whole of the CF in the SC
Added
- + cuneate fasciculus of spinal cord editor note check ontology structure, isa parentage to fasciculus of spinal cord should be inferred. TODO - change definition to be the whole of the CF in the SC

Changes for: cranial appendage

Deleted
- - cranial appendage comment Editor notes: revisit after CARO2 appendage issue is sorted. Note that antennae are appendages that protrude from the head
Added
- + cranial appendage editor note revisit after CARO2 appendage issue is sorted. Note that antennae are appendages that protrude from the head

Changes for: spinal cord segment

Deleted
- - spinal cord segment comment Editor notes: This is currently used loosely to refer to cervical, lumbar, etc as well as the metamerically repeated segments, which may correspond more closely with the ZFA neuromere term
Added
- + spinal cord segment editor note This is currently used loosely to refer to cervical, lumbar, etc as well as the metamerically repeated segments, which may correspond more closely with the ZFA neuromere term

Changes for: cervical vertebra 1 anterior tubercle

Deleted
- - cervical vertebra 1 anterior tubercle SubClassOf skeletal element projection
- - cervical vertebra 1 anterior tubercle SubClassOf tubercle
Added
- + cervical vertebra 1 anterior tubercle SubClassOf bony tubercle

Changes for: anterior tubercle of transverse process of cervical vertebra

Deleted
- - anterior tubercle of transverse process of cervical vertebra SubClassOf skeletal element projection
- - anterior tubercle of transverse process of cervical vertebra SubClassOf tubercle
Added
- + anterior tubercle of transverse process of cervical vertebra SubClassOf bony tubercle

Changes for: posterior tubercle of transverse process of cervical vertebra

Deleted
- - posterior tubercle of transverse process of cervical vertebra SubClassOf skeletal element projection
- - posterior tubercle of transverse process of cervical vertebra SubClassOf tubercle
Added
- + posterior tubercle of transverse process of cervical vertebra SubClassOf bony tubercle

Changes for: oropharyngeal papilla

Deleted
- - oropharyngeal papilla SubClassOf has location some oropharynx
Added
- + oropharyngeal papilla SubClassOf located in some oropharynx

Changes for: integumentary papilla

Deleted
- - integumentary papilla SubClassOf has location some integument
Added
- + integumentary papilla SubClassOf located in some integument

Changes for: cochlear ganglion

Deleted
- - cochlear ganglion comment Editor notes: in BTO this is part of the cochlear modiolus, but this leads to the CG being in both the nervous and skeletal systems
Added
- + cochlear ganglion editor note in BTO this is part of the cochlear modiolus, but this leads to the CG being in both the nervous and skeletal systems

Changes for: lens nucleus

Deleted
- - lens nucleus comment editor note: needs checked; cf nucleus in GO
Added
- + lens nucleus editor note needs checked; cf nucleus in GO

Changes for: epiglottis

Deleted
- - epiglottis comment Editor note: refine definition to better distinguish cartilage from the whole structure
Added
- + epiglottis editor note refine definition to better distinguish cartilage from the whole structure

Changes for: renal medulla

Deleted
- - renal medulla has exact synonym medullary pyramids { database cross reference=FMA:74268 , has synonym type=plural term }
Added
- + renal medulla has related synonym medullary pyramids { database cross reference=FMA:74268 , has synonym type=plural term }

Changes for: ulnar sesamoid bone

Deleted
- - ulnar sesamoid bone comment Editor notes: compare with pisiform
Added
- + ulnar sesamoid bone editor note compare with pisiform

Changes for: myelin

Deleted
- - myelin comment editor note: cede to other ontology. Retired in ncit
Added
- + myelin editor note cede to other ontology. Retired in ncit

Changes for: limbic system

Deleted
- - limbic system SubClassOf anatomical system
Added
- + limbic system SubClassOf anatomical cluster

Changes for: urorectal septum

Deleted
- - urorectal septum comment Editor notes: todo - use to define cloacal septation in GO
Added
- + urorectal septum editor note todo - use to define cloacal septation in GO

Changes for: optic canal

Deleted
- - optic canal has related synonym optic foramen { database cross reference=http://en.wikipedia.org/wiki/Optic_canal }
Added
- + optic canal SubClassOf part of some facial skeleton
- + optic canal database cross reference EHDAA2:0001312
- + optic canal database cross reference EMAPA:18716
- + optic canal has alternative id UBERON:0006269
- + optic canal has exact synonym optic foramen { database cross reference=http://en.wikipedia.org/wiki/Optic_canal }

Changes for: visual cortex

Deleted
- - visual cortex comment Editor note: merge with primary visual cortex? FMA and BTO treat as distinct
Added
- + visual cortex editor note merge with primary visual cortex? FMA and BTO treat as distinct

Changes for: integumentary skeleton

Deleted
- - integumentary skeleton SubClassOf has location some integument
Added
- + integumentary skeleton SubClassOf located in some integument

Changes for: extraembryonic mesoderm

Added
- + extraembryonic mesoderm SubClassOf part of some entire extraembryonic component

Changes for: olfactory system

Added
- + olfactory system SubClassOf existence ends during some fully formed stage

Changes for: paired limb/fin field

Deleted
- - paired limb/fin field comment Editor notes: we represent the field as being a part of the LPM (consistent with ZFA, Gilbert). As a consequence, the relationship between limb bud (with is ectoderm+mesenchyme) stands in a weaker has_developmental_contribution_from relation to the field - TODO implement this.
Added
- + paired limb/fin field editor note we represent the field as being a part of the LPM (consistent with ZFA, Gilbert). As a consequence, the relationship between limb bud (with is ectoderm+mesenchyme) stands in a weaker has_developmental_contribution_from relation to the field - TODO implement this.

Changes for: median fin

Deleted
- - median fin EquivalentTo fin and in median plane of some multi-cellular organism
- - median fin SubClassOf in median plane of some multi-cellular organism
Added
- + median fin EquivalentTo fin and intersects midsagittal plane of some multi-cellular organism
- + median fin SubClassOf intersects midsagittal plane of some multi-cellular organism

Changes for: connecting stalk vasculature

Deleted
- - connecting stalk blood vessel has exact synonym connecting stalk blood vessels { database cross reference=EHDAA2:0000313 , has synonym type=plural term }
- - connecting stalk blood vessel label connecting stalk blood vessel
Added
- + connecting stalk vasculature EquivalentTo vasculature and part of some connecting stalk
- + connecting stalk vasculature SubClassOf vasculature
- + connecting stalk vasculature has exact synonym connecting stalk blood vessels { database cross reference=EHDAA2:0000313 }
- + connecting stalk vasculature has related synonym connecting stalk blood vessel
- + connecting stalk vasculature has related synonym vasculature of connecting stalk
- + connecting stalk vasculature label connecting stalk vasculature

Changes for: major vestibular gland

Added
- + major vestibular gland has exact synonym Bartholin gland

Changes for: regular connective tissue

Deleted
- - regular connective tissue comment Editor notes: the connective tissue hierarchy largely follows FMA with definitions from VSAO. Note that in FMA, loose-CT is irregular-CT. This means regular-CT is necessarily equivalent to dense-regular-CT (assuming a JEPD classification).
Added
- + regular connective tissue editor note the connective tissue hierarchy largely follows FMA with definitions from VSAO. Note that in FMA, loose-CT is irregular-CT. This means regular-CT is necessarily equivalent to dense-regular-CT (assuming a JEPD classification).

Changes for: simple cuboidal epithelium

Deleted
- - simple cuboidal epithelium comment Editor notes: needs to be synchronized with CL - there is no distinct cuboidal cell in CL
Added
- + simple cuboidal epithelium editor note needs to be synchronized with CL - there is no distinct cuboidal cell in CL

Changes for: organism subdivision

Deleted
- - organism subdivision comment Editor note: Reflects CARO2. todo - check the inclusion of FMA ‘cardinal body part here’, and check child terms for consistency
Added
- + organism subdivision editor note Reflects CARO2. todo - check the inclusion of FMA ‘cardinal body part here’, and check child terms for consistency

Changes for: extraembryonic structure

Deleted
- - extraembryonic structure EquivalentTo anatomical structure and adjacent to some embryonic structure and existence starts and ends during some embryo stage
- - extraembryonic structure SubClassOf adjacent to some embryonic structure
- - extraembryonic structure comment see also conceptus extraembryonic component in EHDAA2. Note that the FBbt class is not placed here until the tracker issue is resolved.
- - extraembryonic structure database cross reference EMAPA:16042
- - extraembryonic structure has related synonym extraembryonic component
- - extraembryonic structure see also http://purl.obolibrary.org/obo/FBbt_00005835
Added
- + extraembryonic structure EquivalentTo anatomical structure and part of some entire extraembryonic component
- + extraembryonic structure SubClassOf part of some entire extraembryonic component
- + extraembryonic structure comment see also conceptus extraembryonic component in EHDAA2.
- + extraembryonic structure database cross reference FBbt:00005835

Changes for: tissue

Deleted
- - tissue comment Editor note: changed label and definition to reflect CARO2
Added
- + tissue editor note changed label and definition to reflect CARO2

Changes for: extraembryonic membrane

Added
- + extraembryonic membrane SubClassOf part of some entire extraembryonic component

Changes for: connecting stalk mesoderm

Deleted
- - connecting stalk mesoderm SubClassOf extraembryonic structure
- - connecting stalk mesoderm SubClassOf mesoderm-derived structure
- - connecting stalk mesoderm SubClassOf part of some connecting stalk
Added
- + connecting stalk mesoderm SubClassOf dense mesenchyme tissue
- + connecting stalk mesoderm SubClassOf develops from some extraembryonic mesoderm
- + connecting stalk mesoderm SubClassOf mesenchyme of umbilical cord
- + connecting stalk mesoderm SubClassOf part of some umbilical cord

Changes for: forelimb zeugopod skeleton

Deleted
- - forelimb zeugopod skeleton comment Editor notes: adding proxinally_connected_to humerus causes inconsistencies - requires investigation
Added
- + forelimb zeugopod skeleton editor note adding proxinally_connected_to humerus causes inconsistencies - requires investigation

Changes for: carina of trachea

Deleted
- - carina of trachea SubClassOf connects some main bronchus
- - carina of trachea SubClassOf connects some trachea
Added
- + carina of trachea SubClassOf connects some main bronchus
- + carina of trachea SubClassOf connects some trachea

Changes for: frenulum of tongue

Deleted
- - frenulum of tongue definition The frenulum of tongue (or lingual frenulum) is the frenulum of the tongue, a small fold of mucous membrane extending from the floor of the mouth to the midline of the underside of the tongue. { database cross reference=http://en.wikipedia.org/wiki/Frenulum_of_tongue }
Added
- + frenulum of tongue definition A small fold of mucous membrane extending from the floor of the mouth to the midline of the underside of the tongue. { database cross reference=MGI:anna }

Changes for: posterior fontanelle

Deleted
- - posterior fontanelle SubClassOf connects some lambdoid suture
- - posterior fontanelle SubClassOf connects some sagittal suture
Added
- + posterior fontanelle SubClassOf connects some lambdoid suture
- + posterior fontanelle SubClassOf connects some sagittal suture

Changes for: supraglenoid tubercle

Deleted
- - supraglenoid tubercle SubClassOf skeletal element projection
- - supraglenoid tubercle SubClassOf tubercle
Added
- + supraglenoid tubercle SubClassOf bony tubercle

Changes for: ceratobranchial 5 tooth

Deleted
- - ceratobranchial 5 tooth EquivalentTo calcareous tooth and attaches to some ceratobranchial 5 bone
- - ceratobranchial 5 tooth SubClassOf attaches to some ceratobranchial 5 bone
Added
- + ceratobranchial 5 tooth EquivalentTo calcareous tooth and attaches to some ceratobranchial 5 bone
- + ceratobranchial 5 tooth SubClassOf attaches to some ceratobranchial 5 bone

Changes for: shell

Deleted
- - shell comment Editor notes: may be obsoleted after integumental system overhaul
Added
- + shell editor note may be obsoleted after integumental system overhaul

Changes for: mandibular symphysis

Deleted
- - mandibular symphysis EquivalentTo cartilaginous joint and ObjectMinCardinality( connects dentary ) and ObjectMaxCardinality( connects dentary )
- - mandibular symphysis SubClassOf connects some dentary
Added
- + mandibular symphysis EquivalentTo cartilaginous joint and ObjectMinCardinality( connects dentary ) and ObjectMaxCardinality( connects dentary )
- + mandibular symphysis SubClassOf connects some dentary

Changes for: appendix testis

Deleted
- - appendix testis comment Editor notes: the label hydatid of morgagni is ambiguous w.r.t male vs female. The ncita structure ‘hydatic of morgani[sic]’ is male and thus belongs here. See also ‘vesicular appendage of epoophoron’
Added
- + appendix testis comment ‘ is male and thus belongs here. See also ‘vesicular appendage of epoophoron’
- + appendix testis editor note the label hydatid of morgagni is ambiguous w.r.t male vs female. The ncita structure ‘hydatic of morgani[sic]

Changes for: interphalangeal joint

Deleted
- - interphalangeal joint EquivalentTo skeletal joint and ObjectMinCardinality( connects phalanx ) and ObjectMaxCardinality( connects phalanx )
- - interphalangeal joint SubClassOf connects some phalanx
Added
- + interphalangeal joint EquivalentTo skeletal joint and ObjectMinCardinality( connects phalanx ) and ObjectMaxCardinality( connects phalanx )
- + interphalangeal joint SubClassOf connects some phalanx

Changes for: trigeminal neural crest

Deleted
- - trigeminal neural crest comment Editor note: todo - compare ZFA and EHDAA2 representation
Added
- + trigeminal neural crest editor note todo - compare ZFA and EHDAA2 representation

Changes for: thymus primordium

Deleted
- - thymus primordium comment Editor notes: we follow Kardong table 13.1 in having some developmental contribution of pouch 4 in mammals, but this isn’t reflected in EHDAA2. Development notes: Consider adding distinct term for mesenchyme (see EHDAA2), to indicate NC constribution. Taxon notes: variability of developmental origin: In fish, thymic primordia are generated by all the pouches except the first. However, in avians the thymus arises from pouches 3 and 4, whereas in humans it is only generated by the third pouch[PMID:16313389] The thymus arises from the second pouch in frogs, 2-6 in cartilaginous fish, 2-3 in reptiles, 3 or 4 in bony fish, birds and mammals. The final number is variable - 5 paired organs in sharks, 4 in caecilians, 3 in urodeles, 1 in many teleost, anurans and many mammals[ISBN-10:0781714125]
Added
- + thymus primordium editor note we follow Kardong table 13.1 in having some developmental contribution of pouch 4 in mammals, but this isn’t reflected in EHDAA2. Development notes: Consider adding distinct term for mesenchyme (see EHDAA2), to indicate NC constribution. Taxon notes: variability of developmental origin: In fish, thymic primordia are generated by all the pouches except the first. However, in avians the thymus arises from pouches 3 and 4, whereas in humans it is only generated by the third pouch[PMID:16313389] The thymus arises from the second pouch in frogs, 2-6 in cartilaginous fish, 2-3 in reptiles, 3 or 4 in bony fish, birds and mammals. The final number is variable - 5 paired organs in sharks, 4 in caecilians, 3 in urodeles, 1 in many teleost, anurans and many mammals[ISBN-10:0781714125]

Changes for: pedal digit metatarsal cartilage element

Deleted
- - pedal digit metatarsal cartilage element comment Editor note: EMAPA represents the specific child classes as being part of the digit mesenchyme - we follow this although for the fully formed structure we represent the metatarsals as adjoining rather than being part of the digit skeleton
Added
- + pedal digit metatarsal cartilage element editor note EMAPA represents the specific child classes as being part of the digit mesenchyme - we follow this although for the fully formed structure we represent the metatarsals as adjoining rather than being part of the digit skeleton

Changes for: venous dural sinus

Deleted
- - venous dural sinus comment editor note: the MA placement should be checked
Added
- + venous dural sinus editor note the MA placement should be checked

Changes for: valve of inferior vena cava

Deleted
- - valve of inferior vena cava comment editor note: this class should be subdivided into the embryonic structure and the vestigial adult remnant, a small endocardialfold
Added
- + valve of inferior vena cava editor note this class should be subdivided into the embryonic structure and the vestigial adult remnant, a small endocardialfold

Changes for: urinary system structure

Deleted
- - urinary system structure comment editor note: note that we do not explicitly exclude entities such as WBbt:0005777 (excretory duct) here, but they will be automatically classified under this class after reasoning
Added
- + urinary system structure editor note note that we do not explicitly exclude entities such as WBbt:0005777 (excretory duct) here, but they will be automatically classified under this class after reasoning

Changes for: gastrointestinal system

Added
- + gastrointestinal system SubClassOf existence ends during some fully formed stage

Changes for: frontonasal suture

Deleted
- - frontonasal suture EquivalentTo craniofacial suture and connects some tetrapod frontal bone and connects some nasal bone
- - frontonasal suture SubClassOf connects some nasal bone
- - frontonasal suture SubClassOf connects some tetrapod frontal bone
Added
- + frontonasal suture EquivalentTo craniofacial suture and connects some tetrapod frontal bone and connects some nasal bone
- + frontonasal suture SubClassOf connects some nasal bone
- + frontonasal suture SubClassOf connects some tetrapod frontal bone

Changes for: dorsal telencephalic commissure

Deleted
- - dorsal telencephalic commissure SubClassOf connects some pallium
Added
- + dorsal telencephalic commissure SubClassOf connects some pallium

Changes for: nasal cavity epithelium

Deleted
- - nasal cavity epithelium comment Editor note: this class may in future be split into the embryonic precursor of the oronasal membrane and the structure that is part of the mucosa in the developed organism
Added
- + nasal cavity epithelium editor note this class may in future be split into the embryonic precursor of the oronasal membrane and the structure that is part of the mucosa in the developed organism

Changes for: terminal part of digestive tract

Deleted
- - terminal part of digestive tract has related synonym rectum { database cross reference=FBbt:00005756 }
Added
- + terminal part of digestive tract definition The distalmost portion of the digestive tract, derived from the hindgut, and terminating with the anus. { database cross reference=UBERON:cjm }
- + terminal part of digestive tract has narrow synonym rectum { database cross reference=FBbt:00005756 }

Changes for: adrenal/interrenal gland

Deleted
- - adrenal/interrenal gland comment Editor notes: keep this grouping class so long as it is required for GO
Added
- + adrenal/interrenal gland editor note keep this grouping class so long as it is required for GO

Changes for: interrenal gland

Deleted
- - interrenal gland comment Editor notes: check isa - not a true gland? There are two types of interrenal cells identified (1) The noradrenaline type, which contain heterogeneous vesicles with electron-dense granules located asymmetrically within the vesicular membrane. (2) The adrenaline type, in which the vesicles are smaller and contain homogenous electron-lucent granules that are separated from the vesicular membrane by a visible – halo http://dev.biologists.org/content/130/10/2107.full
Added
- + interrenal gland editor note check isa - not a true gland? There are two types of interrenal cells identified (1) The noradrenaline type, which contain heterogeneous vesicles with electron-dense granules located asymmetrically within the vesicular membrane. (2) The adrenaline type, in which the vesicles are smaller and contain homogenous electron-lucent granules that are separated from the vesicular membrane by a visible – halo http://dev.biologists.org/content/130/10/2107.full

Changes for: cerebellar commissure

Deleted
- - cerebellar commissure EquivalentTo nervous system commissure and connects some left hemisphere of cerebellum and connects some right hemisphere of cerebellum
- - cerebellar commissure SubClassOf connects some left hemisphere of cerebellum
- - cerebellar commissure SubClassOf connects some right hemisphere of cerebellum
Added
- + cerebellar commissure EquivalentTo nervous system commissure and connects some left hemisphere of cerebellum and connects some right hemisphere of cerebellum
- + cerebellar commissure SubClassOf connects some left hemisphere of cerebellum
- + cerebellar commissure SubClassOf connects some right hemisphere of cerebellum

Changes for: root of cranial nerve

Deleted
- - root of cranial nerve comment Editor note: recommend asserting under this class rather than relying on inference, as relations may change
Added
- + root of cranial nerve editor note recommend asserting under this class rather than relying on inference, as relations may change

Changes for: arthropod oviduct

Deleted
- - arthropod oviduct comment Editor notes: this term should be ceded to the arthropod anatomy ontology. Note that this is not even analagous to the class ‘oviduct’ in uberon (as the oviduct is the entire tube, from gonad to outside)
Added
- + arthropod oviduct editor note this term should be ceded to the arthropod anatomy ontology. Note that this is not even analagous to the class ‘oviduct’ in uberon (as the oviduct is the entire tube, from gonad to outside)

Changes for: inter-basipterygium joint

Deleted
- - inter-basipterygium joint EquivalentTo skeletal joint and connects some basipterygium bone and connects some basipterygium cartilage
- - inter-basipterygium joint SubClassOf connects some basipterygium bone
- - inter-basipterygium joint SubClassOf connects some basipterygium cartilage
Added
- + inter-basipterygium joint EquivalentTo skeletal joint and connects some basipterygium bone and connects some basipterygium cartilage
- + inter-basipterygium joint SubClassOf connects some basipterygium bone
- + inter-basipterygium joint SubClassOf connects some basipterygium cartilage

Changes for: inter-premaxillary joint

Deleted
- - inter-premaxillary joint EquivalentTo skeletal joint and connects some premaxilla
- - inter-premaxillary joint SubClassOf connects some premaxilla
Added
- + inter-premaxillary joint EquivalentTo skeletal joint and connects some premaxilla
- + inter-premaxillary joint SubClassOf connects some premaxilla

Changes for: hyomandibular-otic region joint

Deleted
- - hyomandibular-otic region joint EquivalentTo skeletal joint and connects some otic region and connects some hyomandibular bone
- - hyomandibular-otic region joint SubClassOf connects some hyomandibular bone
- - hyomandibular-otic region joint SubClassOf connects some otic region
Added
- + hyomandibular-otic region joint EquivalentTo skeletal joint and connects some otic region and connects some hyomandibular bone
- + hyomandibular-otic region joint SubClassOf connects some hyomandibular bone
- + hyomandibular-otic region joint SubClassOf connects some otic region

Changes for: orbitosphenoid-lateral ethmoid joint

Deleted
- - orbitosphenoid-lateral ethmoid joint EquivalentTo skeletal joint and connects some orbitosphenoid and connects some lateral ethmoid bone
- - orbitosphenoid-lateral ethmoid joint SubClassOf connects some lateral ethmoid bone
- - orbitosphenoid-lateral ethmoid joint SubClassOf connects some orbitosphenoid
Added
- + orbitosphenoid-lateral ethmoid joint EquivalentTo skeletal joint and connects some orbitosphenoid and connects some lateral ethmoid bone
- + orbitosphenoid-lateral ethmoid joint SubClassOf connects some lateral ethmoid bone
- + orbitosphenoid-lateral ethmoid joint SubClassOf connects some orbitosphenoid

Changes for: autopalatine-maxillary joint

Deleted
- - autopalatine-maxillary joint EquivalentTo skeletal joint and connects some maxilla and connects some autopalatine
- - autopalatine-maxillary joint SubClassOf connects some autopalatine
- - autopalatine-maxillary joint SubClassOf connects some maxilla
Added
- + autopalatine-maxillary joint EquivalentTo skeletal joint and connects some maxilla and connects some autopalatine
- + autopalatine-maxillary joint SubClassOf connects some autopalatine
- + autopalatine-maxillary joint SubClassOf connects some maxilla

Changes for: vertebra 4-vertebra 5 joint

Deleted
- - vertebra 4-vertebra 5 joint EquivalentTo skeletal joint and connects some vertebral element 4 and connects some vertebral element 5
- - vertebra 4-vertebra 5 joint SubClassOf connects some vertebral element 4
- - vertebra 4-vertebra 5 joint SubClassOf connects some vertebral element 5
Added
- + vertebra 4-vertebra 5 joint EquivalentTo skeletal joint and connects some vertebral element 4 and connects some vertebral element 5
- + vertebra 4-vertebra 5 joint SubClassOf connects some vertebral element 4
- + vertebra 4-vertebra 5 joint SubClassOf connects some vertebral element 5

Changes for: hyomandibula-metapterygoid joint

Deleted
- - hyomandibula-metapterygoid joint EquivalentTo skeletal joint and connects some hyomandibular bone and connects some metapterygoid
- - hyomandibula-metapterygoid joint SubClassOf connects some hyomandibular bone
- - hyomandibula-metapterygoid joint SubClassOf connects some metapterygoid
Added
- + hyomandibula-metapterygoid joint EquivalentTo skeletal joint and connects some hyomandibular bone and connects some metapterygoid
- + hyomandibula-metapterygoid joint SubClassOf connects some hyomandibular bone
- + hyomandibula-metapterygoid joint SubClassOf connects some metapterygoid

Changes for: chorion-containing eggshell

Added
- + chorion-containing eggshell present in taxon http://purl.obolibrary.org/obo/NCBITaxon_7227 { source=GO }

Changes for: plantaris

Deleted
- - plantaris comment Editor notes: todo - coordinate with phenoscape-ext on representation of amphibian plantaris longus and profundus
Added
- + plantaris editor note todo - coordinate with phenoscape-ext on representation of amphibian plantaris longus and profundus

Changes for: manual digit mesenchyme

Deleted
- - manual digit mesenchyme comment Editor notes: In EHDAA2, the metacarpal cartilage condensation is considered part of the digits - it might be better to call the whole structure digital ray mesenchyme/condensation
Added
- + manual digit mesenchyme editor note In EHDAA2, the metacarpal cartilage condensation is considered part of the digits - it might be better to call the whole structure digital ray mesenchyme/condensation

Changes for: acetabular labrum

Deleted
- - acetabular labrum comment Function notes: Its function is to deepen the acetabulum, making it more difficult for the head of the femur to slip out of place (sublux). Structure notes: some sources treat this as fibrocartilage
Added
- + acetabular labrum comment Structure notes: some sources treat this as fibrocartilage
- + acetabular labrum function notes Its function is to deepen the acetabulum, making it more difficult for the head of the femur to slip out of place (sublux)

Changes for: pectoral complex muscle

Deleted
- - pectoral complex muscle comment Editor notes: the MA class belongs here, based on its current child classes
Added
- + pectoral complex muscle editor note the MA class belongs here, based on its current child classes

Changes for: calcaneofibular ligament

Deleted
- - calcaneofibular ligament EquivalentTo skeletal ligament and connects some fibula and connects some calcaneus
- - calcaneofibular ligament SubClassOf connects some calcaneus
- - calcaneofibular ligament SubClassOf connects some fibula
Added
- + calcaneofibular ligament EquivalentTo skeletal ligament and connects some fibula and connects some calcaneus
- + calcaneofibular ligament SubClassOf connects some calcaneus
- + calcaneofibular ligament SubClassOf connects some fibula

Changes for: medial ligament of ankle joint

Deleted
- - medial ligament of ankle joint EquivalentTo skeletal ligament and connects some tibia and connects some tarsal skeleton
- - medial ligament of ankle joint SubClassOf connects some tarsal skeleton
- - medial ligament of ankle joint SubClassOf connects some tibia
Added
- + medial ligament of ankle joint EquivalentTo skeletal ligament and connects some tibia and connects some tarsal skeleton
- + medial ligament of ankle joint SubClassOf connects some tarsal skeleton
- + medial ligament of ankle joint SubClassOf connects some tibia

Changes for: talofibular ligament

Deleted
- - talofibular ligament EquivalentTo skeletal ligament and connects some fibula and connects some talus
- - talofibular ligament SubClassOf connects some fibula
- - talofibular ligament SubClassOf connects some lateral malleolus of fibula
- - talofibular ligament SubClassOf connects some talus
Added
- + talofibular ligament EquivalentTo skeletal ligament and connects some fibula and connects some talus
- + talofibular ligament SubClassOf connects some fibula
- + talofibular ligament SubClassOf connects some lateral malleolus of fibula
- + talofibular ligament SubClassOf connects some talus

Changes for: extraembryonic tissue

Deleted
- - extraembryonic tissue EquivalentTo tissue and adjacent to some embryonic structure and existence starts and ends during some embryo stage
- - extraembryonic tissue SubClassOf adjacent to some embryonic structure
- - extraembryonic tissue SubClassOf existence starts and ends during some embryo stage
Added
- + extraembryonic tissue EquivalentTo tissue and part of some entire extraembryonic component
- + extraembryonic tissue SubClassOf part of some entire extraembryonic component

Changes for: talocalcaneonavicular joint

Deleted
- - talocalcaneonavicular joint EquivalentTo skeletal joint and connects some calcaneus and connects some navicular bone of pes and connects some talus
- - talocalcaneonavicular joint SubClassOf connects some calcaneus
- - talocalcaneonavicular joint SubClassOf connects some navicular bone of pes
- - talocalcaneonavicular joint SubClassOf connects some talus
Added
- + talocalcaneonavicular joint EquivalentTo skeletal joint and connects some calcaneus and connects some navicular bone of pes and connects some talus
- + talocalcaneonavicular joint SubClassOf connects some calcaneus
- + talocalcaneonavicular joint SubClassOf connects some navicular bone of pes
- + talocalcaneonavicular joint SubClassOf connects some talus

Changes for: calcaneocuboid joint

Deleted
- - calcaneocuboid joint EquivalentTo skeletal joint and connects some calcaneus and connects some cuboid bone
- - calcaneocuboid joint SubClassOf connects some calcaneus
- - calcaneocuboid joint SubClassOf connects some cuboid bone
Added
- + calcaneocuboid joint EquivalentTo skeletal joint and connects some calcaneus and connects some cuboid bone
- + calcaneocuboid joint SubClassOf connects some calcaneus
- + calcaneocuboid joint SubClassOf connects some cuboid bone

Changes for: manubriosternal joint

Deleted
- - manubriosternal joint EquivalentTo skeletal joint and connects some manubrium of sternum and connects some body of sternum
- - manubriosternal joint SubClassOf connects some body of sternum
- - manubriosternal joint SubClassOf connects some manubrium of sternum
Added
- + manubriosternal joint EquivalentTo skeletal joint and connects some manubrium of sternum and connects some body of sternum
- + manubriosternal joint SubClassOf connects some body of sternum
- + manubriosternal joint SubClassOf connects some manubrium of sternum

Changes for: mesotarsal joint

Deleted
- - mesotarsal joint EquivalentTo skeletal joint and connects some distal tarsal bone and connects some proximal tarsal bone
- - mesotarsal joint SubClassOf connects some distal tarsal bone
- - mesotarsal joint SubClassOf connects some proximal tarsal bone
Added
- + mesotarsal joint EquivalentTo skeletal joint and connects some distal tarsal bone and connects some proximal tarsal bone
- + mesotarsal joint SubClassOf connects some distal tarsal bone
- + mesotarsal joint SubClassOf connects some proximal tarsal bone

Changes for: radio-carpal joint

Deleted
- - radio-carpal joint EquivalentTo skeletal joint and connects some radius bone and connects some carpal skeleton
- - radio-carpal joint SubClassOf connects some carpal skeleton
- - radio-carpal joint SubClassOf connects some radius bone
Added
- + radio-carpal joint EquivalentTo skeletal joint and connects some radius bone and connects some carpal skeleton
- + radio-carpal joint SubClassOf connects some carpal skeleton
- + radio-carpal joint SubClassOf connects some radius bone

Changes for: calcar

Deleted
- - calcar comment Function notes: to help spread the interfemoral membrane which is part of the wing membrane between the tail and the hind legs.
Added
- + calcar function notes to help spread the interfemoral membrane which is part of the wing membrane between the tail and the hind legs.

Changes for: coelom

Deleted
- - coelom comment Editor notes: EHDAA2 distingsuishes between the lumen, the lining, and the ‘coelomic cavity’, which despire it’s name, is not a space - it is the aggregate of space plus lining.
Added
- + coelom editor note EHDAA2 distingsuishes between the lumen, the lining, and the ‘coelomic cavity’, which despire it’s name, is not a space - it is the aggregate of space plus lining.

Changes for: crurotarsal joint

Deleted
- - crurotarsal joint EquivalentTo skeletal joint and connects some hindlimb zeugopod skeleton and connects some proximal tarsal bone
- - crurotarsal joint SubClassOf connects some hindlimb zeugopod skeleton
- - crurotarsal joint SubClassOf connects some proximal tarsal bone
Added
- + crurotarsal joint EquivalentTo skeletal joint and connects some hindlimb zeugopod skeleton and connects some proximal tarsal bone
- + crurotarsal joint SubClassOf connects some hindlimb zeugopod skeleton
- + crurotarsal joint SubClassOf connects some proximal tarsal bone

Changes for: forelimb cartilage element

Added
- + forelimb cartilage element has narrow synonym forelimb wing cartilaginous condensation { database cross reference=NCBITaxon:8782 , database cross reference=OBOL:automatic , has synonym type=taxonomic disambiguation }

Changes for: glandular epithelium

Deleted
- - glandular epithelium comment Editor notes: consider splitting epithelium from epithelial tissue
Added
- + glandular epithelium editor note consider splitting epithelium from epithelial tissue

Changes for: arthropod optic lobe

Deleted
- - arthropod optic lobe comment Editor notes: this term should be ceded to the arthropod anatomy ontology
Added
- + arthropod optic lobe editor note this term should be ceded to the arthropod anatomy ontology

Changes for: radius pre-cartilage condensation

Deleted
- - radius pre-cartilage condensation comment Editor notes: still to decide whether this is a distinct pre-cartilage condensation
Added
- + radius pre-cartilage condensation editor note still to decide whether this is a distinct pre-cartilage condensation

Changes for: aorta

Deleted
- - aorta comment Editor notes: This class is currently a mixed bag, encompassing (1) the entirety of the mammalian aorta together with (2) the developmental and phylogenetic homologs of its segments: the ventral aorta and dorsal aortae. Taxon notes: All amniotes have a broadly similar arrangement to that of humans, albeit with a number of individual variations. In fish, however, there are two separate vessels referred to as aortas. The ventral aorta carries de-oxygenated blood from the heart to the gills; part of this vessel forms the ascending aorta in tetrapods (the remainder forms the pulmonary artery). A second, dorsal aorta carries oxygenated blood from the gills to the rest of the body, and is homologous with the descending aorta of tetrapods. The two aortas are connected by a number of vessels, one passing through each of the gills. Amphibians also retain the fifth connecting vessel, so that the aorta has two parallel arches[WP].
Added
- + aorta comment .
- + aorta editor note This class is currently a mixed bag, encompassing (1) the entirety of the mammalian aorta together with (2) the developmental and phylogenetic homologs of its segments: the ventral aorta and dorsal aortae. Taxon notes: All amniotes have a broadly similar arrangement to that of humans, albeit with a number of individual variations. In fish, however, there are two separate vessels referred to as aortas. The ventral aorta carries de-oxygenated blood from the heart to the gills; part of this vessel forms the ascending aorta in tetrapods (the remainder forms the pulmonary artery). A second, dorsal aorta carries oxygenated blood from the gills to the rest of the body, and is homologous with the descending aorta of tetrapods. The two aortas are connected by a number of vessels, one passing through each of the gills. Amphibians also retain the fifth connecting vessel, so that the aorta has two parallel arches[WP]

Changes for: cranial nerve II

Deleted
- - cranial nerve II comment Editor notes: A sensory tract that develops as an outpocketing of the brain - we classify as a cranial nerve as is traditional, but not strictly a nerve. AO notes: (relaion to eye): MA, XAO, AAO and BTO consider this part of the eye. This is in contrast to GO, FMA, EHDAA2 (FMA has a class ‘intra-ocular part of optic nerve’ which represents the region of overlap). Relation to brain: part of diencephalon in EHDAA2, ZFA. In NIF, has the optic nerve root as part, which is a feature part of the diencphalon. Structure notes: We are consistent here with the FMA in considering CN-II continuous with the retina. Editor notes: - determine the precise relationship between CN II and the CNS
Added
- + cranial nerve II comment Editor notes: - determine the precise relationship between CN II and the CNS
- + cranial nerve II editor note A sensory tract that develops as an outpocketing of the brain - we classify as a cranial nerve as is traditional, but not strictly a nerve. AO notes: (relaion to eye): MA, XAO, AAO and BTO consider this part of the eye. This is in contrast to GO, FMA, EHDAA2 (FMA has a class ‘intra-ocular part of optic nerve’ which represents the region of overlap). Relation to brain: part of diencephalon in EHDAA2, ZFA. In NIF, has the optic nerve root as part, which is a feature part of the diencphalon. Structure notes: We are consistent here with the FMA in considering CN-II continuous with the retina

Changes for: corneo-scleral junction

Deleted
- - corneo-scleral junction EquivalentTo anatomical junction and connects some cornea and connects some sclera
- - corneo-scleral junction SubClassOf connects some cornea
- - corneo-scleral junction SubClassOf connects some sclera
Added
- + corneo-scleral junction EquivalentTo anatomical junction and connects some cornea and connects some sclera
- + corneo-scleral junction SubClassOf connects some cornea
- + corneo-scleral junction SubClassOf connects some sclera

Changes for: endocrine system

Added
- + endocrine system SubClassOf existence ends during some fully formed stage

Changes for: posterior commissure

Deleted
- - posterior commissure EquivalentTo nervous system commissure and connects some nucleus of pretectal area
- - posterior commissure SubClassOf connects some nucleus of pretectal area
Added
- + posterior commissure EquivalentTo nervous system commissure and connects some nucleus of pretectal area
- + posterior commissure SubClassOf connects some nucleus of pretectal area

Changes for: stomodeum

Deleted
- - stomodeum comment Editor note: consider indicating location. e.g. anterior. Note some AOs place this as part of oral opening, but it’s not clear when this structure comes into existence. Taxon note: This class groups together disparate structures as all being the anterior part of the early metazoan digestive tract and precursor of the mouth. However, the developmental processes vary, so this class may be split in future. E.g. in mammals it is a rostral depression surrounded by prominences. Outgrowth of the prominences produces a stomodeal cavity.
Added
- + stomodeum comment Taxon note: This class groups together disparate structures as all being the anterior part of the early metazoan digestive tract and precursor of the mouth. However, the developmental processes vary, so this class may be split in future. E.g. in mammals it is a rostral depression surrounded by prominences. Outgrowth of the prominences produces a stomodeal cavity.
- + stomodeum editor note consider indicating location. e.g. anterior. Note some AOs place this as part of oral opening, but it’s not clear when this structure comes into existence

Changes for: zonal layer of superior colliculus

Deleted
- - zonal layer of superior colliculus comment Editor notes: we follow FMA is making this gray matter, but this needs to be reconciled with the WP-derived definition
Added
- + zonal layer of superior colliculus editor note we follow FMA is making this gray matter, but this needs to be reconciled with the WP-derived definition

Changes for: brain

Added
- + brain SubClassOf existence ends during some fully formed stage

Changes for: hippocampal commissure

Deleted
- - hippocampal commissure SubClassOf connects some Ammon’s horn
Added
- + hippocampal commissure SubClassOf connects some Ammon’s horn

Changes for: egg chorion

Added
- + egg chorion SubClassOf part of some entire extraembryonic component

Changes for: canthus

Deleted
- - canthus SubClassOf connects some lower eyelid
- - canthus SubClassOf connects some upper eyelid
Added
- + canthus SubClassOf connects some lower eyelid
- + canthus SubClassOf connects some upper eyelid

Changes for: endoderm

Deleted
- - endoderm comment This class was created automatically from a combination of ontologies

Changes for: obsolete lipid droplet

Deleted
- - obsolete lipid droplet consider FBbt:00000037

Changes for: organismal segment

Deleted
- - organismal segment comment editor note: review this post-CARO2
Added
- + organismal segment editor note review this post-CARO2

Changes for: haltere

Deleted
- - haltere comment Editor notes: this term should be ceded to the arthropod anatomy ontology
Added
- + haltere editor note this term should be ceded to the arthropod anatomy ontology

Changes for: skeletal joint

Deleted
- - skeletal joint SubClassOf connects some skeletal element
Added
- + skeletal joint SubClassOf connects some skeletal element

Changes for: humerus

Added
- + humerus SubClassOf has part some part of some glenohumeral joint
- + humerus SubClassOf shoulder bone

Changes for: antenna

Deleted
- - antenna comment Editor notes: this term should be ceded to the arthropod anatomy ontology
Added
- + antenna editor note this term should be ceded to the arthropod anatomy ontology

Changes for: renal medulla interstitium

Deleted
- - renal medulla interstitium comment Function notes: It functions in renal water reabsorption by building up a high hypertonicity, which draws water out of the thin descending limb of the loop of Henle and the collecting duct system. This hypertonicity, in turn, is created by an efflux of urea from the inner medullary collecting duct.
Added
- + renal medulla interstitium function notes It functions in renal water reabsorption by building up a high hypertonicity, which draws water out of the thin descending limb of the loop of Henle and the collecting duct system. This hypertonicity, in turn, is created by an efflux of urea from the inner medullary collecting duct.

Changes for: seminal vesicle

Deleted
- - seminal vesicle comment Function notes: The seminal vesicles secrete a significant proportion of the fluid that ultimately becomes semen. Lipofuscin granules from dead epithelial cells give the secretion its yellowish color. About 50-70%[2] of the seminal fluid in humans originates from the seminal vesicles, but is not expelled in the first ejaculate fractions which are dominated by spermatozoa and zinc-rich prostatic fluid.
Added
- + seminal vesicle function notes The seminal vesicles secrete a significant proportion of the fluid that ultimately becomes semen. Lipofuscin granules from dead epithelial cells give the secretion its yellowish color. About 50-70%[2] of the seminal fluid in humans originates from the seminal vesicles, but is not expelled in the first ejaculate fractions which are dominated by spermatozoa and zinc-rich prostatic fluid.

Changes for: mammalian vulva

Deleted
- - mammalian vulva comment editor note: todo - add pudendum

Changes for: reproductive system

Deleted
- - reproductive system comment Editor notes: consider splitting genitalia from reproductive system
Added
- + reproductive system SubClassOf existence ends during some fully formed stage
- + reproductive system editor note consider splitting genitalia from reproductive system

Changes for: oviduct

Deleted
- - oviduct SubClassOf connects some female gonad
- - oviduct SubClassOf connects some space surrounding organism
Added
- + oviduct SubClassOf connects some female gonad
- + oviduct SubClassOf connects some space surrounding organism

Report for properties

ObjectProperty objects lost from source: 10

ObjectProperty objects new in target: 1

New ObjectProperty : connects

connects has obo namespace uberon
connects definition Binary relationship: z connects x if and only if there exists some y such that z connects x and y in a ternary connected_to(x,y,z) relationship. { database cross reference=http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern }
connects shorthand connects
connects comment Editors note: this is currently used for both structural relationships (such as between a valve and the chamber it connects) and abstract relationships (anatomical lines and the entities they connect)
connects label connects
connects id connects
connects database cross reference RO:0002176

Changed ObjectProperty objects: 1

Changes for: attaches_to

Deleted
- - SubObjectPropertyOf( attaches to connects )
Added
- + SubObjectPropertyOf( attaches to connects )

May 22, 2014 |
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2014-05-22 release

Ontology Diff Report

Original Ontology

New Ontology

Report for classes

Class objects lost from source: 1

Class objects new in target: 44

New Class : bony tubercle

New Class : dorsal cloacal gland

New Class : horn of hemipenis

New Class : incisive process of premaxilla

New Class : placental caruncle

New Class : placentome of cotyledonary placenta

New Class : intertarsal sesamoid

New Class : primary premolar tooth

New Class : lower primary premolar tooth

New Class : upper primary premolar tooth

New Class : secondary premolar tooth

New Class : epithelium of terminal part of digestive tract

New Class : shoulder joint

New Class : transitional anatomical structure

New Class : entire extraembryonic component

New Class : muscle of terminal part of digestive tract

New Class : periosteum of long bone

New Class : intrahepatic branch of portal vein

New Class : rostral margin of orbit

New Class : upper premolar tooth

New Class : lower premolar tooth

New Class : mesial marginal ridge of tooth

New Class : distal marginal ridge of tooth

New Class : transverse marginal ridge of tooth

New Class : marginal ridge of tooth

New Class : oblique ridge of tooth

New Class : triangular ridge of tooth

New Class : transverse ridge of tooth

New Class : ridge of tooth

New Class : preductal region of aortic arch

New Class : postductal region of aortic arch

New Class : juxtaductal region of aortic arch

New Class : mucus body coating

New Class : mucus cocoon

New Class : metaphysis of fibula

New Class : lingual cusp of tooth

New Class : descending trunk of arch of aorta

New Class : lamina lucida

New Class : vermilion

New Class : frenulum of upper lip

New Class : frenulum of lower lip

New Class : upper vermilion

New Class : lower vermilion

New Class : frenulum of lip

Changed Class objects: 644

Changes for: levator mandibulae externus

Changes for: levator mandibulae articularis

Changes for: levator mandibulae lateralis

Changes for: levator mandibulae longus

Changes for: tonsil germinal center

Changes for: anatomical conduit space

Changes for: subarcualis rectus I

Changes for: trunk maxillary-mandibularis

Changes for: anatomical line between inner canthi

Changes for: bone of upper jaw

Changes for: dentary tooth

Changes for: cell condensation

Changes for: non-mineralized cartilage tissue

Changes for: subdivision of organism along main body axis

Changes for: thyrohyoid bone

Changes for: thyrohyoid cartilage

Changes for: tympanohyoid cartilage

Changes for: external cervical os

Changes for: intermammary line

Changes for: utriculosaccular duct

Changes for: genital swelling

Changes for: pterygoideus

Changes for: midcarpal joint

Changes for: pisiform joint

Changes for: ramus auricularis of the vagus nerve

Changes for: nasomaxillary suture

Changes for: levator quadrati

Changes for: ramus muscularis of glossopharyngeus nerve